Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sam Hobson"'
Autor:
Sam Hobson, Emmanouil Mavrogeorgis, Tianlin He, Justyna Siwy, Thomas Ebert, Karolina Kublickiene, Peter Stenvinkel, Harald Mischak
Publikováno v:
Proteomes, Vol 11, Iss 3, p 25 (2023)
Given the pathophysiological continuum of chronic kidney disease (CKD), different molecular determinants affecting progression may be associated with distinct disease phases; thus, identification of these players are crucial for guiding therapeutic d
Externí odkaz:
https://doaj.org/article/8ca749335db0444c81edfab574baf4c8
Autor:
Sam Hobson, Samsul Arefin, Awahan Rahman, Leah Hernandez, Thomas Ebert, Henriette de Loor, Pieter Evenepoel, Peter Stenvinkel, Karolina Kublickiene
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3640 (2023)
Kidney transplantation (KTx) is the preferred form of renal replacement therapy in chronic kidney disease (CKD) patients, owing to increased quality of life and reduced mortality when compared to chronic dialysis. Risk of cardiovascular disease is re
Externí odkaz:
https://doaj.org/article/9f71e31df1be4db79b8fd972e68d925b
Autor:
Jonas Laget, Sam Hobson, Karen Muyor, Flore Duranton, Irene Cortijo, Piotr Bartochowski, Bernard Jover, Anne-Dominique Lajoix, Magnus Söderberg, Thomas Ebert, Peter Stenvinkel, Àngel Argilés, Karolina Kublickiene, Nathalie Gayrard
Publikováno v:
Cells, Vol 12, Iss 4, p 643 (2023)
Increased senescent cell burden and dysregulation of the nuclear factor erythroid 2–related factor 2 (NRF2) pathway have been associated with numerous age-related pathologies; however, their role in promoting vascular calcification (VC) in chronic
Externí odkaz:
https://doaj.org/article/c25174718b5240b4abe46e889bee39e3
Autor:
Sam Hobson, Henriette de Loor, Karolina Kublickiene, Joachim Beige, Pieter Evenepoel, Peter Stenvinkel, Thomas Ebert
Publikováno v:
Toxins, Vol 14, Iss 6, p 412 (2022)
Patients with kidney failure (KF) have a high incidence of cardiovascular (CV) disease, partly driven by insufficient clearance of uremic toxins. Recent investigations have questioned the accepted effects of adverse lipid profile and CV risk in uremi
Externí odkaz:
https://doaj.org/article/41056724402d41789c53da547b8e0471
Autor:
Thomas Ebert, Sven-Christian Pawelzik, Anna Witasp, Samsul Arefin, Sam Hobson, Karolina Kublickiene, Paul G. Shiels, Magnus Bäck, Peter Stenvinkel
Publikováno v:
Toxins, Vol 12, Iss 4, p 227 (2020)
Persistent low-grade inflammation and premature ageing are hallmarks of the uremic phenotype and contribute to impaired health status, reduced quality of life, and premature mortality in chronic kidney disease (CKD). Because there is a huge global bu
Externí odkaz:
https://doaj.org/article/6906bc1801be44999323ec0474306d45
Publikováno v:
Toxins, Vol 11, Iss 2, p 82 (2019)
Together with bone-mineral disorders, premature vascular ageing is a common feature of the uremic phenotype. A detailed understanding of mechanisms involved remains unclear and warrants further research. Available treatment options for end stage rena
Externí odkaz:
https://doaj.org/article/f9478f2c03b54739ad05aea6f007327e
Autor:
Ebert, Sam Hobson, Henriette de Loor, Karolina Kublickiene, Joachim Beige, Pieter Evenepoel, Peter Stenvinkel, Thomas
Publikováno v:
Toxins; Volume 14; Issue 6; Pages: 412
Patients with kidney failure (KF) have a high incidence of cardiovascular (CV) disease, partly driven by insufficient clearance of uremic toxins. Recent investigations have questioned the accepted effects of adverse lipid profile and CV risk in uremi
Autor:
Jonas Laget, Sam Hobson, Karen Muyor, Flore Duranton, Irene Cortijo, Piotr Bartochowski, Bernard Jover, Anne Dominique Lajoix, Peter Stenvinkel, Angel Argiles Ciscart, Karolina Kublickiene, Nathalie Gayrard
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Vascular dysfunction including vascular calcification (VC), is a consequence of ageing and chronic kidney disease (CKD) that increase the risk of cardiovascular events. Accumulation of senescent cells in arteries can lead to struc
Autor:
Sam Hobson, Jonas Laget, Karen Muyor, Irene Cortijo, Piotr Bartochowski, Bernard Jover, Anne Dominique Lajoix, Thomas Ebert, Peter Stenvinkel, Angel Argiles Ciscart, Nathalie Gayrard, Karolina Kublickiene
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Vascular calcification is a clinical sequelae of chronic kidney disease (CKD) that is associated with high cardiovascular-related mortality in end-stage kidney failure (ESKF) patients. Increased senescent cell burden and dysregula