Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Sam Harirforoosh"'
Autor:
Dustin L. Cooper, Sam Harirforoosh
Publikováno v:
MethodsX, Vol 1, Iss C, Pp 49-55 (2014)
Rebamipide is a mucoprotective agent commonly used to prevent nonsteriodal anti-inflammatory drug-induced gastrointenstinal side effects [1]. Human plasma and urine analysis of rebamipide utilizing high performance liquid chromatography (HPLC) have b
Externí odkaz:
https://doaj.org/article/82c763c4a576482eb9c9e0e9c1ae98f2
Autor:
Dustin L Cooper, Sam Harirforoosh
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113558 (2014)
Polymer based nanoparticle formulations have been shown to increase drug bioavailability and/or reduce drug adverse effects. Nonsteroidal anti-inflammatory drugs (e.g. celecoxib) reduce prostaglandin synthesis and cause side effects such as gastroint
Externí odkaz:
https://doaj.org/article/8b53c7ff66484a16b01920022bf4361f
Exacerbation of celecoxib-induced renal injury by concomitant administration of misoprostol in rats.
Autor:
Dustin L Cooper, Derek E Murrell, Christopher M Conder, Victoria E Palau, Grace E Campbell, Shaun P Lynch, James W Denham, Angela V Hanley, Kenny W Bullins, Peter C Panus, Krishna Singh, Sam Harirforoosh
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89087 (2014)
Nonsteroidal anti-inflammatory drugs (NSAIDs) can produce adverse effects by inhibiting prostaglandin (PG) synthesis. A PGE1 analogue, misoprostol, is often utilized to alleviate NSAID-related gastrointestinal side effects. This study examined the ef
Externí odkaz:
https://doaj.org/article/e877bbf4891f4ae0bbc314cca3e84ab9
Autor:
Dustin L Cooper, Sam Harirforoosh
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87326 (2014)
Drug based nanoparticle (NP) formulations have gained considerable attention over the past decade for their use in various drug formulations. NPs have been shown to increase bioavailability, decrease side effects of highly toxic drugs, and prolong dr
Externí odkaz:
https://doaj.org/article/55ed603456354d428dcc4bf66c0c7fa2
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 16, Iss 5 (2014)
Non-steroidal anti-inflammatory drugs (NSAIDs) are used chronically to reduce pain and inflammation in patients with arthritic conditions, and also acutely as analgesics by many patients. Both therapeutic and adverse effects of NSAIDs are due to inhi
Externí odkaz:
https://doaj.org/article/24ffd7110d5e48839c17e964457689b3
Autor:
Christan M Thomas, Robert C Wood, Jarrett E Wyatt, Morgan H Pendleton, Ruben D Torrenegra, Oscar E Rodriguez, Sam Harirforoosh, Maria Ballester, Janet Lightner, Koyamangalath Krishnan, Victoria P Ramsauer
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39806 (2012)
Over 4000 flavonoids have been identified so far and among these, many are known to have antitumor activities. The basis of the relationships between chemical structures, type and position of substituent groups and the effects these compounds exert s
Externí odkaz:
https://doaj.org/article/c6d88e20a1594c258d7e5ca6a2e98104
Autor:
David G Menter, Victoria P Ramsauer, Sam Harirforoosh, Kanishka Chakraborty, Peiying Yang, Linda Hsi, Robert A Newman, Koyamangalath Krishnan
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28813 (2011)
3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) inhibitors, commonly known as statins, may possess cancer preventive and therapeutic properties. Statins are effective suppressors of cholesterol synthesis with a well-established risk-benefit r
Externí odkaz:
https://doaj.org/article/32ec334c7acb403180dbabb4978977f7
Autor:
Russell W. Fankhouser, Derek E. Murrell, Yaa Y. Anane, David L. Hurley, Hadii M. Mamudu, Sam Harirforoosh
Publikováno v:
Drug Metabolism and Personalized Therapy. 37:375-382
Objectives This study sought to identify potential pharmacogenetic associations of selected enzymes and transporters with type 2 diabetes (T2D). In addition, pharmacogenomic profiles, concentrations of asymmetric dimethylarginine (ADMA) or kidney inj
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 44:591-609
Pain management in the pediatric population is complex for many reasons. Mild pain is usually managed quite well with oral acetaminophen or ibuprofen. Situations involving more severe pain often require the use of an opioid, which may be administered
Publikováno v:
Clinical Drug Investigation. 38:573-577
The US Food and Drug Administration (FDA) is encouraging the innovation of long-acting opioid formulations that are manipulation-resistant. The purpose of this commentary is to assess the benefits and limitations of abuse-deterrent opioid formulation