Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sam H. Au"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract During metastatic dissemination, circulating tumour cells (CTCs) enter capillary beds, where they experience mechanical constriction forces. The transient and persistent effects of these forces on CTCs behaviour remain poorly understood. Her
Externí odkaz:
https://doaj.org/article/8c6b62cd608b4979a2124884edbcf442
Autor:
Sam H. Au, Jon Edd, Amy E. Stoddard, Keith H. K. Wong, Fabio Fachin, Shyamala Maheswaran, Daniel A. Haber, Shannon L. Stott, Ravi Kapur, Mehmet Toner
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Circulating tumor cell clusters (CTC clusters) are potent initiators of metastasis and potentially useful clinical markers for patients with cancer. Although there are numerous devices developed to isolate individual circulating tumor cells
Externí odkaz:
https://doaj.org/article/0d495c2a2b8a41feaa99b11421967de5
Autor:
Sam H. Au
Publikováno v:
Engineering and Physical Approaches to Cancer ISBN: 9783031228018
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a998621290b1d8eb874a1c4d905b02d3
https://doi.org/10.1007/978-3-031-22802-5_10
https://doi.org/10.1007/978-3-031-22802-5_10
Autor:
Julian F. Ashby, Julien Schmidt, Neelima KC, Armand Kurum, Caroline Koch, Alexandre Harari, Li Tang, Sam H. Au
No T cell receptor (TCR) T cell therapies have obtained clinical approval. The lack of strategies capable of selecting and recovering potent T cell candidates may be a contributor to this. Existing protocols for selecting TCR T cell clones for cell t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5336da005e32ec1256a2e87acc2642e
http://hdl.handle.net/10044/1/97869
http://hdl.handle.net/10044/1/97869
Publikováno v:
British Journal of Cancer
During metastasis, tumour cells navigating the vascular circulatory system—circulating tumour cells (CTCs)—encounter capillary beds, where they start the process of extravasation. Biomechanical constriction forces exerted by the microcirculation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c4be2425bebcfa1f9a8039eb06e6e1
https://doi.org/10.1038/s41416-020-01176-x
https://doi.org/10.1038/s41416-020-01176-x
Publikováno v:
Clinical & Experimental Metastasis
The behaviour of circulating tumour cells in the microcirculation remains poorly understood. Growing evidence suggests that biomechanical adaptations and interactions with blood components, i.e. immune cells and platelets within capillary beds, may a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c196870cf3f41b3747c794f9b31bb914
https://pubmed.ncbi.nlm.nih.gov/34241735
https://pubmed.ncbi.nlm.nih.gov/34241735
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
3D printed and paper-based microfluidics are promising formats for applications that require portable miniaturized fluid handling such as point-of-care testing. These two formats deployed in isolation, however, have inherent limitations that hamper t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee705359914447f4cb044dcabb67021
https://pubmed.ncbi.nlm.nih.gov/33110199
https://pubmed.ncbi.nlm.nih.gov/33110199
Autor:
Sam H. Au
Publikováno v:
Science Translational Medicine. 11
Bioinspired valveless impedance pumps are driven by contracting rings of tissue engineered muscle cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cacafd4f8deeff609d9a026f2c589713
https://doi.org/10.1126/scitranslmed.aaw5317
https://doi.org/10.1126/scitranslmed.aaw5317
Autor:
Sam H. Au
Publikováno v:
Science Translational Medicine. 10
Coencapsulation of T cells and target cells into arrays of subnanoliter droplets improves the identification of functional T cell receptors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df6e35bf927b72ef90079c3487cb5e0b
https://doi.org/10.1126/scitranslmed.aav9144
https://doi.org/10.1126/scitranslmed.aav9144
Autor:
Sam H. Au
Publikováno v:
Science Translational Medicine. 10
Amphiphilic polymeric microneedles dissolve into nanomicelles that inhibit tumor growth.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23bd3b35ee156038a99eff83591779da
https://doi.org/10.1126/scitranslmed.aav0343
https://doi.org/10.1126/scitranslmed.aav0343