Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Sam Griffiths-Jones"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Parhyale hawaiensis has emerged as the crustacean model of choice due to its tractability, ease of imaging, sequenced genome, and development of CRISPR/Cas9 genome editing tools. However, transcriptomic datasets spanning embryonic developmen
Externí odkaz:
https://doaj.org/article/6e99bbaea61749db80981ab31820820c
Autor:
Jon Stott, Thomas Wright, Jannah Holmes, Julie Wilson, Sam Griffiths-Jones, Deborah Foster, Barry Wright
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287131 (2023)
AimsTo identify differential expression of shorter non-coding RNA (ncRNA) genes associated with autism spectrum disorders (ASD).BackgroundncRNA are functional molecules that derive from non-translated DNA sequence. The HUGO Gene Nomenclature Committe
Externí odkaz:
https://doaj.org/article/be9191a2c8fc477ba23a54cbcb1d72d6
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 4 (2022)
AbstractMicroRNAs can have subtle and combinatorial effects on the levels of the targets and pathways they act on. Studying the consequences of a single microRNA knockout often proves difficult as many such knockouts exhibit phenotypes only under str
Externí odkaz:
https://doaj.org/article/8a38f2ab48a14eaf8be4de928c056a02
Autor:
Nicolae Herndon, Jennifer Shelton, Lizzy Gerischer, Panos Ioannidis, Maria Ninova, Jürgen Dönitz, Robert M. Waterhouse, Chun Liang, Carsten Damm, Janna Siemanowski, Peter Kitzmann, Julia Ulrich, Stefan Dippel, Georg Oberhofer, Yonggang Hu, Jonas Schwirz, Magdalena Schacht, Sabrina Lehmann, Alice Montino, Nico Posnien, Daniela Gurska, Thorsten Horn, Jan Seibert, Iris M. Vargas Jentzsch, Kristen A. Panfilio, Jianwei Li, Ernst A. Wimmer, Dominik Stappert, Siegfried Roth, Reinhard Schröder, Yoonseong Park, Michael Schoppmeier, Ho-Ryun Chung, Martin Klingler, Sebastian Kittelmann, Markus Friedrich, Rui Chen, Boran Altincicek, Andreas Vilcinskas, Evgeny Zdobnov, Sam Griffiths-Jones, Matthew Ronshaugen, Mario Stanke, Sue J. Brown, Gregor Bucher
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background The red flour beetle Tribolium castaneum has emerged as an important model organism for the study of gene function in development and physiology, for ecological and evolutionary genomics, for pest control and a plethora of other t
Externí odkaz:
https://doaj.org/article/d7f08d6886f3424bbf7f5c6e2f6a7099
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 4 (2021)
Externí odkaz:
https://doaj.org/article/1045d29f6ba1477295a4f3d5c03a2b52
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-16 (2017)
Abstract Background Piwi-interacting RNAs (piRNAs) are a class of short (~26–31-nucleotide) non-protein-coding RNAs expressed in the metazoan germline. The piRNA pathway in arthropods is best understood in the ovary of Drosophila melanogaster, wher
Externí odkaz:
https://doaj.org/article/105c3fd2a5a9497a9b753e945d9fff30
Autor:
Evelyn E. Schwager, Prashant P. Sharma, Thomas Clarke, Daniel J. Leite, Torsten Wierschin, Matthias Pechmann, Yasuko Akiyama-Oda, Lauren Esposito, Jesper Bechsgaard, Trine Bilde, Alexandra D. Buffry, Hsu Chao, Huyen Dinh, HarshaVardhan Doddapaneni, Shannon Dugan, Cornelius Eibner, Cassandra G. Extavour, Peter Funch, Jessica Garb, Luis B. Gonzalez, Vanessa L. Gonzalez, Sam Griffiths-Jones, Yi Han, Cheryl Hayashi, Maarten Hilbrant, Daniel S. T. Hughes, Ralf Janssen, Sandra L. Lee, Ignacio Maeso, Shwetha C. Murali, Donna M. Muzny, Rodrigo Nunes da Fonseca, Christian L. B. Paese, Jiaxin Qu, Matthew Ronshaugen, Christoph Schomburg, Anna Schönauer, Angelika Stollewerk, Montserrat Torres-Oliva, Natascha Turetzek, Bram Vanthournout, John H. Werren, Carsten Wolff, Kim C. Worley, Gregor Bucher, Richard A. Gibbs, Jonathan Coddington, Hiroki Oda, Mario Stanke, Nadia A. Ayoub, Nikola-Michael Prpic, Jean-François Flot, Nico Posnien, Stephen Richards, Alistair P. McGregor
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-27 (2017)
Abstract Background The duplication of genes can occur through various mechanisms and is thought to make a major contribution to the evolutionary diversification of organisms. There is increasing evidence for a large-scale duplication of genes in som
Externí odkaz:
https://doaj.org/article/7f4bb216c9a44bfe9d385085f175f1b4
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 8919 (2020)
In eukaryotes, microRNAs (miRNAs) have roles in development, homeostasis, disease and the immune response. Recent work has shown that plant and mammalian miRNAs also mediate cross-kingdom and cross-domain communications. However, these studies remain
Externí odkaz:
https://doaj.org/article/612e57f593f74fcd8a1eb1798e516dc9
Autor:
Steven Parker, Marcin G Fraczek, Jian Wu, Sara Shamsah, Alkisti Manousaki, Kobchai Dungrattanalert, Rogerio Alves de Almeida, Edith Invernizzi, Tim Burgis, Walid Omara, Sam Griffiths-Jones, Daniela Delneri, Raymond T O'Keefe
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007253 (2018)
Noncoding RNAs (ncRNAs) are emerging as key regulators of cellular function. We have exploited the recently developed barcoded ncRNA gene deletion strain collections in the yeast Saccharomyces cerevisiae to investigate the numerous ncRNAs in yeast wi
Externí odkaz:
https://doaj.org/article/8b35311aa8174fb69cbdc7632eb1f55c
Autor:
Paul P Gardner, Mario Fasold, Sarah W Burge, Maria Ninova, Jana Hertel, Stephanie Kehr, Tammy E Steeves, Sam Griffiths-Jones, Peter F Stadler
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121797 (2015)
Here we present the results of a large-scale bioinformatics annotation of non-coding RNA loci in 48 avian genomes. Our approach uses probabilistic models of hand-curated families from the Rfam database to infer conserved RNA families within each avia
Externí odkaz:
https://doaj.org/article/408ad17cc92d45ac9267402cd81489ed