Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sam Garnett"'
Autor:
David Dankort, Ran Shu, Kendall Dutchak, Veronique Provencher-Tom, Angeline de Bruyns, Sam Garnett
Figure S1. Creation of Inducible-BRAF-Inducible Senescent Cells. Figure S2. Summary of lentiviral based shRNA screen for OIS targets. Figure S3. Knockdown of IAPP expression by shRNA. Figure S4. Perturbation of IAPP and ERK2. Figure S5. Loss of IAPP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9279aec7b064c73e552a234726291e45
https://doi.org/10.1158/1541-7786.22526931
https://doi.org/10.1158/1541-7786.22526931
Oncogenic activation of the RTK–RAS–RAF–MEK–ERK pathway occurs in approximately 25% of all human cancers, yet activated RAS, BRAF, or MEK expression in primary cells leads to a prolonged and predominantly irreversible cell-cycle arrest termed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c52339d8e8b749ccb4b15a9ff8594702
https://doi.org/10.1158/1541-7786.c.6545418.v1
https://doi.org/10.1158/1541-7786.c.6545418.v1
Supplementary Figure from MOB3A Bypasses BRAF and RAS Oncogene-Induced Senescence by Engaging the Hippo Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed2a7447bd77eedd85464cb64bf6777
https://doi.org/10.1158/1541-7786.22527408.v1
https://doi.org/10.1158/1541-7786.22527408.v1
Publikováno v:
Molecular Cancer Research. 20:770-781
Oncogenic activation of the RTK–RAS–RAF–MEK–ERK pathway occurs in approximately 25% of all human cancers, yet activated RAS, BRAF, or MEK expression in primary cells leads to a prolonged and predominantly irreversible cell-cycle arrest termed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13784558913d3d3651df793d7c6ff0d
https://doi.org/10.1158/1541-7786.mcr-21-0767
https://doi.org/10.1158/1541-7786.mcr-21-0767
Autor:
Sam Garnett, Angeline de Bruyns, David Dankort, Kendall L. Dutchak, Veronique Provencher-Tom, Ran Shu
Publikováno v:
Molecular Cancer Research. 19:874-885
Cellular senescence is characterized by a prolonged and predominantly irreversible cell-cycle arrest state, which is linked to loss of tissue function and aging in mammals. Moreover, in response to aberrant oncogenic signals such as those from oncoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5b022f7c86a6c8efa85cd9b165174b
https://doi.org/10.1158/1541-7786.mcr-20-0879
https://doi.org/10.1158/1541-7786.mcr-20-0879