Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Sam F. Cooper"'
1
Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters
Autor: Nabil G. Seidah, Sam F. Cooper, Michel Chrétien, Upen K. Banik, Andree G. Roberge, Ajoy Basak
Publikováno v: Biochemical Journal. 338:107-113
Studies were performed to investigate the prohormone/proprotein convertase (PC)-inhibitory properties of chemical constituents of the medicinally active plant Andrographis paniculata (AP; from the family Acanthaceae), also known as ‘King of Bitters
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::313ff8cdfabf5c13ed92879aae1d9151
https://doi.org/10.1042/bj3380107
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2
Presence of N-nitrosodiethanolamine contamination in Canadian metal-working fluids
Autor: Sam F. Cooper, Sami Fadlallah, G. Perrault, G. Truchon, J. Lesage
Publikováno v: Science of The Total Environment. 196:197-204
N-Nitroso compounds are notorious mutagens, carcinogens and teratogens that can be seriously hazardous to human health. Metal-working fluids (MWFs) are used for lubricating and cooling the cutting and grinding surfaces of metal-working machines. Beca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40920ae8c772120a0f46cc618ff7e6d4
https://doi.org/10.1016/s0048-9697(96)05400-9
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4
Determination of atrazine, its degradation products and metolachlor in runoff water and sediments using solid-phase extraction
Autor: Sam F. Cooper, Pierre Lafrance, Hassan Sabik, Josette M. Fournier
Publikováno v: Talanta. 42:717-724
In order to determine the fate of the herbicides atrazine (as well as some of its degradation products) and metolachlor in water and sediments, a method was developed to extract and analyse these compounds. The two matrices were separated completely
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589b83d26c6bfdcb950215ef48a64704
https://doi.org/10.1016/0039-9140(95)01476-r
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5
Determination of the enantiomers of bunolol in human urine by high-performance liquid chromatography on a chiral AGP stationary phase and identification of their metabolites by gas chromatography—mass spectrometry
Autor: Sam F. Cooper, Feng Li, Michel Côté, Christiane Ayotte
Publikováno v: Journal of Chromatography B: Biomedical Sciences and Applications. 660:327-339
A high-performance liquid chromatographic method using a chiral AGP column was developed to screen and determine the enantiomers of bunolol in human urine. The recovery of (+)- and (-)-bunolol from urine was 91.79-95.23% at different concentrations.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa45c8ee47f3bbf37a31d578b707e67
https://doi.org/10.1016/0378-4347(94)00295-9
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6
Assessment of N-Nitrosodimethylamine Dna Adducts in Rat Hepatocytes by High Performance Liquid Chromatography and Immunosorbent Assay
Autor: S. Fadlallah, Saad Mansour, Krzysztof Krzystyniak, Michel Fournier, M. Lachapelle, F. Guertin, Francine Denizeau, Sam F. Cooper
Publikováno v: International Journal of Environmental Analytical Chemistry. 56:165-174
A rapid and efficient enzyme-linked immunosorbent assay (ELISA) for quantification of DNA adducts was developed using affinity-purified, polyclonal antibodies directed against O6-methylguanosine (O6-meGuo) coupled to bovine serum albumin (BSA). The s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f2e3b7593e26ac40de566b7afddb1e1
https://doi.org/10.1080/03067319408039803
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7
Identification and determination of the enantiomers of moprolol and their metabolites in human urine by high-performance liquid chromatography and gas chromatography—mass spectrometry
Autor: Sam F. Cooper, Michel Côté, Feng Li, Honggang Bi
Publikováno v: Journal of Chromatography B: Biomedical Sciences and Applications. 622:187-195
A simple and sensitive high-performance liquid chromatographic (HPLC) method using chiral derivatization was developed to screen and determine the enantiomers of moprolol and their metabolites in human urine. The recovery of (+)- and (−)-moprolol f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3572fc35a6173be952a39cb390447369
https://doi.org/10.1016/0378-4347(93)80265-6
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8
The metabolism of piperidine-type phenothiazine antipsychotic agents. II. Sulforidazine in dog and human
Autor: Kamal K. Midha, Sam F. Cooper, Gordon McKay, Edward M. Hawes, G. Lin, E. D. Korchinski
Publikováno v: Xenobiotica. 23:27-36
1. The metabolism of sulforidazine was studied in female dogs and adult male humans after oral administration of 37.5 mg and 25.0 mg, respectively. 2. Metabolites in organic extracts of dog urine were separated by h.p.l.c. and individually collected
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2989653aaa8844f3b289cd51510d25
https://doi.org/10.3109/00498259309059359
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10
Determination of N-Nitroso Compounds in the Environment of a Metal Factory Using Metalworking Fluids
Autor: Sam F. Cooper, Daniel Drolet, Sami Fadlallah, Guy Perrault, Michel Fournier
Publikováno v: International Journal of Environmental Analytical Chemistry. 39:281-288
By use of GLC-ECD and HPLC-TEA techniques for N-nitroso compounds, N-nitroso-diethanolamine (NDELA) has been found in concentrations of 1.4–6.0 μg/m3 and 1.3–5.0μg/m3 respectively in all four air samples collected in the environment of a metalw
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08d2eb4a01aed715a041bf3c59ee07c7
https://doi.org/10.1080/03067319008032071
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