Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sam Duwé"'
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102730- (2023)
Summary: The procedures used routinely for collagen and lipofuscin evaluation are, in many cases, qualitative, observer dependent, and disregard spatial distribution. Here, we present a protocol for automatic quantification and spatial characterizati
Externí odkaz:
https://doaj.org/article/191cf88c5f604bbc85d3b4ea02a649cc
Autor:
Ashley M. Rozario, Sam Duwé, Cade Elliott, Riley B. Hargreaves, Gregory W. Moseley, Peter Dedecker, Donna R. Whelan, Toby D. M. Bell
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background The integrity of microtubule filament networks is essential for the roles in diverse cellular functions, and disruption of its structure or dynamics has been explored as a therapeutic approach to tackle diseases such as cancer. Mi
Externí odkaz:
https://doaj.org/article/3678b1bacfc74e5eb70407f362ea8228
Autor:
Laura García-Mendívil, María Pérez-Zabalza, Konstantinos Mountris, Sam Duwé, Nick Smisdom, Marta Pérez, Lluís Luján, Esther Wolfs, Ronald B. Driesen, José María Vallejo-Gil, Pedro Carlos Fresneda-Roldán, Javier Fañanás-Mastral, Manuel Vázquez-Sancho, Marta Matamala-Adell, Juan Fernando Sorribas-Berjón, Javier André Bellido-Morales, Francisco Javier Mancebón-Sierra, Alexánder Sebastián Vaca-Núñez, Carlos Ballester-Cuenca, Aida Oliván-Viguera, Emiliano Diez, Laura Ordovás, Esther Pueyo
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103822- (2022)
Summary: Age-related fibrosis in the left ventricle (LV) has been mainly studied in animals by assessing collagen content. Using second-harmonic generation microscopy and image processing, we evaluated amount, aggregation and spatial distribution of
Externí odkaz:
https://doaj.org/article/9e20c6751f95457bbf486b1eec24443c
Autor:
Hana Valenta, Siewert Hugelier, Sam Duwé, Giulia Lo Gerfo, Marcel Müller, Peter Dedecker, Wim Vandenberg
Publikováno v:
Biophysical Reports, Vol 1, Iss 2, Pp 100026- (2021)
Multicolor fluorescence imaging is an excellent method for the simultaneous visualization of multiple structures, although it is limited by the available spectral window. More labels can be measured by distinguishing these on properties, such as thei
Externí odkaz:
https://doaj.org/article/dc37e708950f4e82a2bfaa29e64e5bf1
Autor:
Wouter Van Genechten, Liesbeth Demuyser, Sam Duwé, Wim Vandenberg, Patrick Van Dijck, Peter Dedecker
Publikováno v:
mSphere, Vol 6, Iss 2 (2021)
ABSTRACT Fluorescence microscopy is a standard research tool in many fields, although collecting reliable images can be difficult in systems characterized by low expression levels and/or high background fluorescence. We present the combination of a p
Externí odkaz:
https://doaj.org/article/679017a1209d45e6bedd2ccb467200b1
Publikováno v:
Cell Reports, Vol 14, Iss 2, Pp 390-400 (2016)
It has become increasingly clear that protein-protein interactions (PPIs) are compartmentalized in nanoscale domains that define the biochemical architecture of the cell. Despite tremendous advances in super-resolution imaging, strategies to observe
Externí odkaz:
https://doaj.org/article/6a796ca48df340b3a6dafa063c739e0d
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 9, p 2015 (2017)
Reversibly switchable fluorescent proteins (RSFPs) enable advanced fluorescence imaging, though the performance of this imaging crucially depends on the properties of the labels. We report on the use of an existing small binding peptide, named Enhanc
Externí odkaz:
https://doaj.org/article/431881a3e1d54dc99c44dfdd1715005d
Autor:
Riley B. Hargreaves, Sam Duwé, Ashley M. Rozario, Alison M. Funston, Rico F. Tabor, Peter Dedecker, Donna R. Whelan, Toby D. M. Bell
Publikováno v:
ACS Bio & Med Chem Au.
Autor:
Laura García Mendívil, María Pérez Zabalza, Konstantinos Mountris, Francisco Javier Mancebón Sierra, Alexánder Sebastián Vaca Núñez, Sam Duwé, Laura Ordovás, Esther Pueyo
Publikováno v:
Jornada de Jóvenes Investigadores del I3A. 10
La edad es un factor de riesgo arrítmico que, en especies animales, está asociado a la remodelación del colágeno. En este trabajo caracterizamos la dinámica tisular del colágeno asociada a la edad en el ventrículo izquierdo humano y utilizamos
Autor:
Mehran Khorshid, Peter Dedecker, Michael Wübbenhorst, Derick Yongabi, Olivier Deschaume, Stijn Jooken, Patricia Losada-Pérez, Alessia Gennaro, Carmen Bartic, Sam Duwé, Patrick Wagner
Publikováno v:
ACS Applied Materials & Interfaces, 12
Cell–material interactions are crucial for many biomedical applications, including medical implants, tissue engineering, and biosensors. For implants, while the adhesion of eukaryotic host cells is desirable, bacterial adhesion often leads to infec