Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sam Buckberry"'
Autor:
Mitchell Bestry, Alexander N Larcombe, Nina Kresoje, Emily K Chivers, Chloe Bakker, James P Fitzpatrick, Elizabeth J Elliott, Jeffrey M Craig, Evelyne Muggli, Jane Halliday, Delyse Hutchinson, Sam Buckberry, Ryan Lister, Martyn Symons, David Martino
Publikováno v:
eLife, Vol 12 (2024)
Alcohol consumption in pregnancy can affect genome regulation in the developing offspring but results have been contradictory. We employed a physiologically relevant murine model of short-term moderate prenatal alcohol exposure (PAE) resembling commo
Externí odkaz:
https://doaj.org/article/3cc646f5fecb4ca6a990a0f7852fc124
Autor:
Alex de Mendoza, Trung Viet Nguyen, Ethan Ford, Daniel Poppe, Sam Buckberry, Jahnvi Pflueger, Matthew R. Grimmer, Sabine Stolzenburg, Ozren Bogdanovic, Alicia Oshlack, Peggy J. Farnham, Pilar Blancafort, Ryan Lister
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-31 (2022)
Abstract Background Cytosine DNA methylation is widely described as a transcriptional repressive mark with the capacity to silence promoters. Epigenome engineering techniques enable direct testing of the effect of induced DNA methylation on endogenou
Externí odkaz:
https://doaj.org/article/b7e0ceb7c87f42b496fd72cdb8d5a2de
Autor:
Alexandra Grubman, Xin Yi Choo, Gabriel Chew, John F. Ouyang, Guizhi Sun, Nathan P. Croft, Fernando J. Rossello, Rebecca Simmons, Sam Buckberry, Dulce Vargas Landin, Jahnvi Pflueger, Teresa H. Vandekolk, Zehra Abay, Yichen Zhou, Xiaodong Liu, Joseph Chen, Michael Larcombe, John M. Haynes, Catriona McLean, Sarah Williams, Siew Yeen Chai, Trevor Wilson, Ryan Lister, Colin W. Pouton, Anthony W. Purcell, Owen J. L. Rackham, Enrico Petretto, Jose M. Polo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Microglia associated with Aβ plaques may have a distinct transcriptional signature compared to those in plaque-free areas of the brain in Alzheimer’s disease (AD) models. Here the authors show that amyloid plaque phagocytosis is associated with a
Externí odkaz:
https://doaj.org/article/9f55b1d1d77043558956af5abec4909b
Autor:
Alex de Mendoza, Amandine Bonnet, Dulce B. Vargas-Landin, Nanjing Ji, Hongfei Li, Feng Yang, Ling Li, Koichi Hori, Jahnvi Pflueger, Sam Buckberry, Hiroyuki Ohta, Nedeljka Rosic, Pascale Lesage, Senjie Lin, Ryan Lister
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Cytosine methyltransferases (DNMTs) often silence transposons in eukaryotic genomes. Here the authors describe the recurrent acquisition of DNMTs by transposons from two distantly-related eukaryotes and suggest that methylation of CG dinucleotides by
Externí odkaz:
https://doaj.org/article/3297be576e064a6fa4a2ceb931910d37
Autor:
Christian M. Nefzger, Fernando J. Rossello, Joseph Chen, Xiaodong Liu, Anja S. Knaupp, Jaber Firas, Jacob M. Paynter, Jahnvi Pflueger, Sam Buckberry, Sue Mei Lim, Brenda Williams, Sara Alaei, Keshav Faye-Chauhan, Enrico Petretto, Susan K. Nilsson, Ryan Lister, Mirana Ramialison, David R. Powell, Owen J.L. Rackham, Jose M. Polo
Publikováno v:
Cell Reports, Vol 21, Iss 10, Pp 2649-2660 (2017)
Summary: Our current understanding of induced pluripotent stem cell (iPSC) generation has almost entirely been shaped by studies performed on reprogramming fibroblasts. However, whether the resulting model universally applies to the reprogramming pro
Externí odkaz:
https://doaj.org/article/fcf8a1ac389940f5bfb79e4118d8977d
Autor:
Cristina Valensisi, Colin Andrus, Sam Buckberry, Naresh Doni Jayavelu, Riikka J. Lund, Ryan Lister, R. David Hawkins
Publikováno v:
Cell Reports, Vol 20, Iss 6, Pp 1448-1462 (2017)
We currently lack a comprehensive understanding of the mechanisms underlying neural tube formation and their contributions to neural tube defects (NTDs). Developing a model to study such a complex morphogenetic process, especially one that models hum
Externí odkaz:
https://doaj.org/article/9227b4c82fa84eb1abf1331038744f6c
Autor:
Benjamin Mayne, Tina Bianco-Miotto, Sam Buckberry, James Breen, Vicki Clifton, Cheryl Shoubridge, Claire Trelford Roberts
Publikováno v:
Frontiers in Genetics, Vol 7 (2016)
The severity and prevalence of many diseases are known to differ between the sexes. Organ specific sex-biased gene expression may underpin these and other sexually dimorphic traits. To further our understanding of sex differences in transcriptional r
Externí odkaz:
https://doaj.org/article/706995620fad4514914d03e249c66578
Autor:
Alex de Mendoza, Amandine Bonnet, Dulce B. Vargas-Landin, Nanjing Ji, Hongfei Li, Feng Yang, Ling Li, Koichi Hori, Jahnvi Pflueger, Sam Buckberry, Hiroyuki Ohta, Nedeljka Rosic, Pascale Lesage, Senjie Lin, Ryan Lister
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of the author Hongfei Li, which was incorrectly given as Fei Hong. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/3a722731f3ed42feba32bfacd97d6c88
Autor:
Rebecca L Wilson, Sam Buckberry, Fleur Spronk, Jessica A Laurence, Shalem Leemaqz, Sean O'Leary, Tina Bianco-Miotto, Jing Du, Paul H Anderson, Claire T Roberts
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131287 (2015)
Vitamin D deficiency has been implicated in the pathogenesis of several pregnancy complications attributed to impaired or abnormal placental function, but there are few clues indicating the mechanistic role of vitamin D in their pathogenesis. To furt
Externí odkaz:
https://doaj.org/article/9c08c4a5c8b14f69aa9c72d62641e7dc
Autor:
Sam Buckberry, Fleur Spronk, Rebecca L. Wilson, Jessica A. Laurence, Tina Bianco-Miotto, Shalem Leemaqz, Sean O'Leary, Paul H. Anderson, Claire T. Roberts
Publikováno v:
Genomics Data, Vol 6, Iss C, Pp 72-73 (2015)
The effects of vitamin D are mediated through the vitamin D receptor (VDR), a predominantly nuclear receptor, expressed in numerous tissues including the placenta. VDR and the retinoid X receptor (RXR) form a dimer complex which binds to genomic vita
Externí odkaz:
https://doaj.org/article/27583e17228440aab372dd5c3d7d37f9