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Publikováno v:
Toxicological Sciences. 135:81-90
Activation of the aryl hydrocarbon receptor (AhR) by its prototypic ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), induces potent suppression of an acute graft-versus-host (GVH) response and prevents GVH disease (GVHD). Suppression is associated
Publikováno v:
The Journal of Immunology. 188:176.5-176.5
The aryl hydrocarbon receptor (AhR) is a promising target for the treatment of immune-mediated diseases. Activation of AhR by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) results in potent immunosuppression in a murine graft versus host (GVH) model, co