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pro vyhledávání: '"Sam Blanchett"'
Phosphorylation of RIPK1 serine 25 mediates IKK dependent control of extrinsic cell death in T cells
Autor:
Sam Blanchett, Yves Dondelinger, Alessandro Barbarulo, Mathieu J. M. Bertrand, Benedict Seddon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The Inhibitor of Kappa B Kinase (IKK) complex is a critical regulator of NF-κB activation. More recently, IKK has also been shown to repress RIPK1 dependent extrinsic cell death pathways by directly phosphorylating RIPK1 at serine 25. In T cells, IK
Externí odkaz:
https://doaj.org/article/19e6cf8ee5f842abb86b828c6755a8fa
Publikováno v:
Trends in immunology. 42(1)
NF-κB signaling is required at multiple stages of T cell development and function. The NF-κB pathway integrates signals from many receptors and involves diverse adapters and kinases. Recent advances demonstrate that kinases controlling NF-κB activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237432834f75a702ff3d38543209ccca
https://pubmed.ncbi.nlm.nih.gov/33246882
https://pubmed.ncbi.nlm.nih.gov/33246882
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2136
The isolation of a single Group A Streptococcus (GAS) virulence determinant in functional investigations is challenging, as GAS employs a multitude of virulence factors. The redundancy between many surface proteins such as adhesins also adds complexi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dddbfe1f8c1a706399b5f61cb130eb38
https://pubmed.ncbi.nlm.nih.gov/32430819
https://pubmed.ncbi.nlm.nih.gov/32430819
Publikováno v:
Methods in Molecular Biology ISBN: 9781071604663
The isolation of a single Group A Streptococcus (GAS) virulence determinant in functional investigations is challenging, as GAS employs a multitude of virulence factors. The redundancy between many surface proteins such as adhesins also adds complexi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb6ae802f995a6af3d1068f37c61faab
https://doi.org/10.1007/978-1-0716-0467-0_11
https://doi.org/10.1007/978-1-0716-0467-0_11
Autor:
Callum Chalmers, Sam Blanchett, Thomas Proft, Dasun Wagachchi, Jacelyn M. S. Loh, Jia Yun Tsai
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Peptide vaccines are an attractive strategy to engineer the induction of highly targeted immune responses and avoid potentially allergenic and/or reactogenic protein regions. However, peptides by themselves are often unstable and poorly immunogenic,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02414e0283e0ec32885a5451a59237b
http://europepmc.org/articles/PMC5803258
http://europepmc.org/articles/PMC5803258