Výsledky vyhledávání - "Sam Blakeman"

Selective particle attention: Rapidly and flexibly selecting features for deep reinforcement learning

Publikováno v: Neural networks : the official journal of the International Neural Network Society. 150

Deep Reinforcement Learning (RL) is often criticised for being data inefficient and inflexible to changes in task structure. Part of the reason for these issues is that Deep RL typically learns end-to-end using backpropagation, which results in task-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b34d8cf45259014eae42ebc6bc66078
https://pubmed.ncbi.nlm.nih.gov/35358888

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Hippocampal α7 nicotinic ACh receptors contribute to modulation of depression-like behaviour in C57BL/6J mice

Autor: Marina R. Picciotto, Tenna N. Mose, Sam Blakeman, Yann S. Mineur

Publikováno v: British Journal of Pharmacology. 175:1903-1914

Background and purpose Clinical studies have identified links between cholinergic signalling and depression in human subjects. Increased cholinergic signalling in hippocampus also increases behaviours related to anxiety and depression in mice, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d821f6b707ced14e0c83824326520f3
https://doi.org/10.1111/bph.13769

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A Complementary Learning Systems approach to Temporal Difference Learning

Autor: Denis Mareschal, Sam Blakeman

Publikováno v: Neural Networks

Complementary Learning Systems (CLS) theory suggests that the brain uses a\ud 'neocortical' and a 'hippocampal' learning system to achieve complex behavior.\ud These two systems are complementary in that the 'neocortical' system relies on\ud slow lea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7debe8bb072cb69d7568e9d5f981ba33
https://eprints.bbk.ac.uk/id/eprint/29596/8/29596a.pdf

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Expression of the 5-HT1A Serotonin Receptor in the Hippocampus Is Required for Social Stress Resilience and the Antidepressant-Like Effects Induced by the Nicotinic Partial Agonist Cytisine

Autor: Emily B. Einstein, Sylvia A Newbold, Matthew P. Bentham, Marina R. Picciotto, Mattis B. Wigestrand, Yann S. Mineur, Sam Blakeman

Publikováno v: Neuropsychopharmacology. 40:938-946

Nicotinic acetylcholine receptor (nAChR) blockers potentiate the effects of selective serotonin reuptake inhibitors (SSRIs) in some treatment-resistant patients; however, it is not known whether these effects are independent, or whether the two neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe0d0302f958496a56df7e6d2e56d87
https://doi.org/10.1038/npp.2014.269

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Multiple Nicotinic Acetylcholine Receptor Subtypes in the Mouse Amygdala Regulate Affective Behaviors and Response to Social Stress

Autor: Sam Blakeman, Yann S. Mineur, Marina R. Picciotto, Gianna M. Fote, Sylvia A Newbold, Emma L.M. Cahuzac

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 41(6)

Electrophysiological and neurochemical studies implicate cholinergic signaling in the basolateral amygdala (BLA) in behaviors related to stress. Both animal studies and human clinical trials suggest that drugs that alter nicotinic acetylcholine recep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b94649b72b6d084f38ff7496164e472
https://pubmed.ncbi.nlm.nih.gov/26471256

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