Výsledky vyhledávání - "Sam Blackburn"

Quantification of frequent-hitter behavior based on historical high-throughput screening data

Autor: J. Willem M. Nissink, Sam Blackburn

Publikováno v: Future medicinal chemistry. 6(10)

Aim: We mine historical high-throughput data to identify and characterize 'frequent hitters', hits that are potentially false-positive results. Background: A key problem in the field of high-throughput screening (HTS) is recognition of frequent hitte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d74eeab4ae81b4092c2e4546cd4902
https://pubmed.ncbi.nlm.nih.gov/25078133

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Stratified high-throughput screening sets enable flexible screening strategies from a single plated collection

Autor: Stefan Schmitt, Sam Blackburn, J. Willem M. Nissink, Stephen W. Peters

Publikováno v: Journal of biomolecular screening. 19(3)

Customized compound picking and plating of very large corporate screening decks (many 100,000s) for high-throughput screening is generally restricted, both from a time and cost perspective. Here we present a stratified screening deck with accompanyin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d5e57aae074b7a1ff0b810ffb797c1
https://pubmed.ncbi.nlm.nih.gov/23918919

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