Výsledky vyhledávání - "Sam A. Deadwyler"

Akademický článek

Developing a hippocampal neural prosthetic to facilitate human memory encoding and recall of stimulus features and categories

Publikováno v: Frontiers in Computational Neuroscience, Vol 18 (2024)

ObjectiveHere, we demonstrate the first successful use of static neural stimulation patterns for specific information content. These static patterns were derived by a model that was applied to a subject’s own hippocampal spatiotemporal neural codes

Externí odkaz: https://doaj.org/article/bae731737b054129adade7716064f04d

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Akademický článek

Patterned Hippocampal Stimulation Facilitates Memory in Patients With a History of Head Impact and/or Brain Injury

Publikováno v: Frontiers in Human Neuroscience, Vol 16 (2022)

Rationale: Deep brain stimulation (DBS) of the hippocampus is proposed for enhancement of memory impaired by injury or disease. Many pre-clinical DBS paradigms can be addressed in epilepsy patients undergoing intracranial monitoring for seizure local

Externí odkaz: https://doaj.org/article/dc8f9735ed494958967e30a340ab05fd

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Akademický článek

Role of Cannabinoid Receptors in Memory Storage

Autor: Robert E. Hampson, Sam A. Deadwyler

Publikováno v: Neurobiology of Disease, Vol 5, Iss 6, Pp 474-482 (1998)

Studies have shown that Δ9-tetrahydrocannabinol, the principal psychoactive ingredient in marijuana, produces memory deficits similar to those produced by neurochemical lesions of the hippocampus. Such lesions impair performance in short-term spatia

Externí odkaz: https://doaj.org/article/e69c9f7c1ce14982870a87092fb5adac

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Multi-Input, Multi-Output Neuronal Mode Network Approach to Modeling the Encoding Dynamics and Functional Connectivity of Neural Systems

Autor: Robert E. Hampson, Theodore W. Berger, Kunling Geng, Dae C. Shin, Vasilis Z. Marmarelis, Dong Song, Sam A. Deadwyler

Publikováno v: Neural Comput

This letter proposes a novel method, multi-input, multi-output neuronal mode network (MIMO-NMN), for modeling encoding dynamics and functional connectivity in neural ensembles such as the hippocampus. Compared with conventional approaches such as the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07829574d60d8e0fc6281adf4e7672ba
https://doi.org/10.1162/neco_a_01204

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Hippocampal CA1 and CA3 neural recording in the human brain: validation of depth electrode placement through high-resolution imaging and electrophysiology

Autor: Christopher T. Whitlow, Gautam Popli, Daniel E. Couture, Alexander S Dakos, Robert E. Hampson, Adrian W. Laxton, Robert T. Wicks, Dustin Fetterhoff, Sam A. Deadwyler, Brent M Roeder, Mark R. Witcher

Publikováno v: Neurosurgical focus. 49(1)

OBJECTIVEIntracranial human brain recordings typically utilize recording systems that do not distinguish individual neuron action potentials. In such cases, individual neurons are not identified by location within functional circuits. In this paper,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449245023fce7558346151a5e80c5295
https://pubmed.ncbi.nlm.nih.gov/32610296

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Mechanism-Based and Input-Output Modeling of the Key Neuronal Connections and Signal Transformations in the CA3-CA1 Regions of the Hippocampus

Autor: Dong Song, Dae C. Shin, Kunling Geng, Vasilis Z. Marmarelis, Robert E. Hampson, Sam A. Deadwyler, Theodore W. Berger

Publikováno v: Neural Computation. 30:149-183

This letter examines the results of input-output (nonparametric) modeling based on the analysis of data generated by a mechanism-based (parametric) model of CA3-CA1 neuronal connections in the hippocampus. The motivation is to obtain biological insig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6904bba04bb20126b903f25b9b4deab2
https://doi.org/10.1162/neco_a_01031

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Cerebrovascular Remodeling and Neuroinflammation is a Late Effect of Radiation-Induced Brain Injury in Non-Human Primates

Autor: David B. Hanbury, Ann M. Peiffer, J. Mark Cline, J. Daniel Bourland, Janet A. Tooze, Linda J. Metheny-Barlow, Robert E. Hampson, Sam A. Deadwyler, Rachel N. Andrews

Publikováno v: Radiation Research. 187:599-611

Fractionated whole-brain irradiation (fWBI) is a mainstay of treatment for patients with intracranial neoplasia; however late-delayed radiation-induced normal tissue injury remains a major adverse consequence of treatment, with deleterious effects on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4898ad8c767731335c9b287b2b8dfc
https://doi.org/10.1667/rr14616.1

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