Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Salwa R. Arafa"'
Autor:
Victor R. Santos, Raymund Y.K. Pun, Salwa R. Arafa, Candi L. LaSarge, Shane Rowley, Shadi Khademi, Tom Bouley, Katherine D. Holland, Norberto Garcia-Cairasco, Steve C. Danzer
Publikováno v:
Neurobiology of Disease, Vol 108, Iss , Pp 339-351 (2017)
Deletion of the mTOR pathway inhibitor PTEN from postnatally-generated hippocampal dentate granule cells causes epilepsy. Here, we conducted field potential, whole cell recording and single cell morphology studies to begin to elucidate the mechanisms
Externí odkaz:
https://doaj.org/article/74ce67b9679e498481eae3c323676666
Autor:
Venkat Suru, Steve C. Danzer, Kimberly L. Kraus, Kevin D. Gaitonde, Benjamin A. Packard, Aynara C. Wulsin, Salwa R. Arafa, James P. Herman
Publikováno v:
Exp Neurol
Objective Glucocorticoid levels rise rapidly following status epilepticus and remain elevated for weeks after the injury. To determine whether glucocorticoid receptor activation contributes to the pathological sequelae of status epilepticus, mice wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cb6c4bca42de5f13de3d34516f1c8a
https://europepmc.org/articles/PMC8169587/
https://europepmc.org/articles/PMC8169587/
Autor:
Tom Bouley, Katherine D. Holland, Candi L. LaSarge, Salwa R. Arafa, Raymund Y. K. Pun, Shane Rowley, Norberto Garcia-Cairasco, Steve C. Danzer, Shadi Khademi, Victor R. Santos
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Neurobiology of Disease, Vol 108, Iss, Pp 339-351 (2017)
Universidade de São Paulo (USP)
instacron:USP
Neurobiology of Disease, Vol 108, Iss, Pp 339-351 (2017)
Deletion of the mTOR pathway inhibitor PTEN from postnatally-generated hippocampal dentate granule cells causes epilepsy. Here, we conducted field potential, whole cell recording and single cell morphology studies to begin to elucidate the mechanisms
Publikováno v:
Experimental neurology. 311
Loss of the mTOR pathway negative regulator PTEN from hippocampal dentate granule cells leads to neuronal hypertrophy, increased dendritic branching and aberrant basal dendrite formation in animal models. Similar changes are evident in humans with mT