Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Salwa, Sebti"'
Autor:
Zhenyi An, Wei-Chung Chiang, Álvaro F. Fernández, Luis H. Franco, CongCong He, Shu-Yi Huang, Eunmyong Lee, Yang Liu, Salwa Sebti, Sanae Shoji-Kawata, Shyam Sirasanagandla, Richard C. Wang, Yongjie Wei, Yuting Zhao, Silvia Vega-Rubin-de-Celis
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
With great sadness, the scientific community received the news of the loss of Beth Levine on 15 June 2020. Dr. Levine was a pioneer in the autophagy field and work in her lab led not only to a better understanding of the molecular mechanisms regulati
Externí odkaz:
https://doaj.org/article/2060115b1cc8482bb2b9de96a0294242
Autor:
Hao Tang, Salwa Sebti, Rossella Titone, Yunyun Zhou, Ciro Isidoro, Theodora S. Ross, Hanina Hibshoosh, Guanghua Xiao, Milton Packer, Yang Xie, Beth Levine
Publikováno v:
EBioMedicine, Vol 2, Iss 3, Pp 255-263 (2015)
Both BRCA1 and Beclin 1 (BECN1) are tumor suppressor genes, which are in close proximity on the human chromosome 17q21 breast cancer tumor susceptibility locus and are often concurrently deleted. However, their importance in sporadic human breast can
Externí odkaz:
https://doaj.org/article/61c0e5751840485da3f3e0231949ad8f
Autor:
Josephine W. Thinwa, Zhongju Zou, Emily Parks, Salwa Sebti, Kelvin Hui, Yongjie Wei, Vibha Singh, Greg Urquhart, Jenna L. Jewell, Julie K. Pfeiffer, Beth Levine, Tiffany A. Reese, Michael U. Shiloh
Virophagy, the selective autophagosomal engulfment and degradation of viral components, is crucial for antiviral immunity. However, the mechanisms leading to viral antigen recognition and autophagy induction remain poorly understood. Here, we identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a14f446e39a5beb9926a75ec48ecd15
https://doi.org/10.1101/2022.09.20.508746
https://doi.org/10.1101/2022.09.20.508746
Publikováno v:
Autophagy.
Macroautophagy/autophagy is necessary for lifespan extension in multiple model organisms and autophagy dysfunction impacts age-related phenotypes and diseases. Introduction of an F121A mutation into the essential autophagy protein BECN1 constitutivel
Autor:
Sophie Pattingre, Alicia Meléndez, Congcong He, Salwa Sebti, J. Marie Hardwick, Diane E. Griffin, Ana Maria Cuervo
Publikováno v:
The FEBS Journal. 287:4314-4321
Beth Levine was a remarkable scientist who launched the burgeoning field of autophagy. The biological process of autophagy was beginning to gain attention through new genetic studies in yeast when Beth Levine's transformative work on the genetics of
Autophagy is necessary for lifespan extension in multiple model organisms and autophagy dysfunction impacts age-related phenotypes and diseases. Introduction of an F121A mutation into the essential autophagy protein BECN1 constitutively increases bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3df3d870aab4e03779c83e15deaaba45
https://doi.org/10.1101/2022.01.12.475960
https://doi.org/10.1101/2022.01.12.475960
Macroautophagy/autophagy is necessary for lifespan extension in multiple model organisms and autophagy dysfunction impacts age-related phenotypes and diseases. Introduction of an F121A mutation into the essential autophagy protein BECN1 constitutivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e399ca9dcc416839a4db76962e24fb65
Autor:
Toshiro Saito, Nina Kaludercic, Federico Pietrocola, Maria Chiara Maiuri, Susmita Kaushik, Álvaro F. Fernández, Sebastiano Sciarretta, Francesca Castoldi, Jihoon Nah, Tomokazu Murakawa, Lorenza Iolanda Tsansizi, Martina Semenzato, Julio Madrigal-Matute, Risa Mukai, Yun Chen, Jumpei Ito, Salwa Sebti, Jenny de Bruijn
Publikováno v:
Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2020, 116 (3), pp.483-504. ⟨10.1093/cvr/cvz233⟩
Cardiovascular Research, 2020, 116 (3), pp.483-504. ⟨10.1093/cvr/cvz233⟩
Cardiovascular Research, Oxford University Press (OUP), 2020, 116 (3), pp.483-504. ⟨10.1093/cvr/cvz233⟩
Cardiovascular Research, 2020, 116 (3), pp.483-504. ⟨10.1093/cvr/cvz233⟩
Autophagy is a highly conserved recycling mechanism essential for maintaining cellular homeostasis. The pathophysiological role of autophagy has been explored since its discovery 50 years ago, but interest in autophagy has grown exponentially over th
Autor:
Salwa Sebti, Álvaro F. Fernández, Chenran Wang, Michael Haas, Jun-Lin Guan, Syn Kok Yeo, Zhongju Zou, Beth Levine
Publikováno v:
Autophagy
Macroautophagy/autophagy is emerging as a major pathway that regulates both aging and stem cell function. Previous studies have demonstrated a positive correlation of autophagy with longevity; however, these studies did not directly address the conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae85b1ad430cc5e0b7b7d718c3b0162
https://europepmc.org/articles/PMC8942493/
https://europepmc.org/articles/PMC8942493/
Autor:
Lucile Espert, Salwa Sebti, Leila El Kebriti, Romain Ragimbeau, Nadine Houede, Andrei Turtoi, Giuseppe Arena, Abdelhay Boulahtouf, Céline Gongora, Sophie Pattingre, Elise Fourgous
Publikováno v:
FASEB Journal
FASEB Journal, 2021, 35 (2), ⟨10.1096/fj.202000930R⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (2), ⟨10.1096/fj.202000930R⟩
FASEB Journal, 2021, 35 (2), ⟨10.1096/fj.202000930R⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (2), ⟨10.1096/fj.202000930R⟩
International audience; Bcl-2-associated athanogen-6 (BAG6) is a nucleocytoplasmic shuttling protein involved in protein quality control. We previously demonstrated that BAG6 is essential for autophagy by regulating the intracellular localization of