Výsledky vyhledávání - "Salvatore Zaru"

Mitochondrial toxicity and body shape changes during nucleos(t)ide analogues administration in patients with chronic hepatitis B

Autor: Salvatore Zaru, Diego F. Calvisi, Paola Bagella, Silvia Ortu, M. Melis, Giovanni Garrucciu, Giordano Madeddu, Alberto Augusto Muredda, Sergio Babudieri, Franco Bandiera, Vito Fiore, Franca Mannu

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports

Our study purpose was to evaluate mitochondrial (mt)DNA and RNA in peripheral blood mononuclear cells (PBMCs) and body shape changes (BSC) in HBV-infected patients. mtDNA and mtRNA were measured in PBMCs. The presence of BSC was evaluated through a q

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d679868d20394291f99055b0d9073c0
https://doi.org/10.1038/s41598-020-58837-3

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Peginterferon ??-2a and ribavirin versus peginterferon ??-2a monotherapy in early virological responders and peginterferon ??-2a and ribavirin versus peginterferon ??-2a, ribavirin and amantadine triple therapy in early virological nonresponders: the SMIEC II trial in na??ve patients with chronic hepatitis C

Publikováno v: European Journal of Gastroenterology & Hepatology. 20:680-687

ObjectiveThe objective of this study was to compare the efficacy of anti-hepatitis C virus (anti-HCV) treatment schedules on the basis of an early virological response (EVR), defined as undetectable serum HCV-RNA (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::206f8f41eee40628fde989023388c2e8
https://doi.org/10.1097/meg.0b013e3282f5196c

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A randomized controlled trial of amantadine plus interferon-α2a vs. interferon-α2a alone in naive patients with chronic hepatitis C randomized according to the early virological response to interferon-α2a monotherapy

Autor: G Parruti, M Cepparulo, Salvatore Zaru, G Sabusco, S Gentile, F Di Candilo, Luigi Demelia, A Tosti, Antonio Grieco, R Della Vecchia, A. Barlattani, L Tarquini, G. De Sanctis, Simona Francioso, Mario Angelico, Francesco Angelico

Publikováno v: Alimentary Pharmacology & Therapeutics. 19:339-347

Summary Background : An early virological response to interferon-α treatment is a strong predictor of sustained response, but it has never been exploited to stratify patients in clinical trials. Aim : To evaluate the efficacy of amantadine plus inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a5afdf88cf8e0f9192d313676229db7
https://doi.org/10.1111/j.1365-2036.2004.01843.x

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A simple rule to personalize standard dual therapy across all genotypes in naive chronic hepatitis C patients: The TT4 randomized trial

Background Rapid and early virological responses to peginterferon-alpha and ribavirin are predictive of sustained virological response (SVR) in hepatitis C virus (HCV) infection. We aimed at finding a simple rule to determine the shortest duration of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea54a08fcc659d9643c454130ab5a4c
http://hdl.handle.net/11573/559645

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Body fat changes and mitochondrial alterations during HBV treatment: a warning for long term administration

Autor: Giordano Madeddu, Sergio Babudieri, Salvatore Zaru, Franca Mannu, Andrea Soddu, Maria Stella Mura, Alberto Augusto Muredda, Franco Bandiera, Giovanni Garrucciu

Publikováno v: The Journal of infection. 65(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e286d276a4bf843698efbd6c0892c9
https://pubmed.ncbi.nlm.nih.gov/22796021

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502 Peginterferon alpha-2A (40KD) monotherapy vs peginterferon alpha-2A and ribavirin in naïve patients with chronic hepatitis C: Preliminary results of the SMIEC II trial in patients with early viral clearance on peginterferon monotherapy

Autor: S Gentile, Pierluigi Tarquini, Antonio Grieco, Laura Ponti, Salvatore Zaru, Orazio Sorbello, A. Barlattani, Francesco Angelico, R Della Vecchia, B. Koehler Horst, P. Guarascio, Luigi Demelia, Paola Piccolo, F. Soccorsi, Simona Francioso, Franco Bandiera, Mario Angelico, Giuseppe Forlini

Publikováno v: Journal of Hepatology. 40:148

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8922a339a4b07f76ff43908035cf733c
https://doi.org/10.1016/s0168-8278(04)90502-8

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