Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Salvatore Mascia"'
Autor:
Fan Liu, Sujay D. Bagi, Qinglin Su, Rajshree Chakrabarti, Rita Barral, Janaka C. Gamekkanda, Chuntian Hu, Salvatore Mascia
Publikováno v:
Organic Process Research & Development. 26:3190-3203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::579bc9739ffeb7c4a4d7082a3ee7dccb
https://doi.org/10.1021/acs.oprd.2c00277
https://doi.org/10.1021/acs.oprd.2c00277
Autor:
Qinglin Su, Paul Hermant, Federica Casati, Bhakti Halkude, Wei Wu, Anjana Ramnath, Atul Dubey, Stephen Born, Bayan Takizawa, Salvatore Mascia
Publikováno v:
AIChE Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d16fe92cd19038c6e8463a81f5bdb9f1
https://doi.org/10.1002/aic.18124
https://doi.org/10.1002/aic.18124
Autor:
Wei Wu, Christopher J. Testa, Khrystyna Shvedova, Salvatore Mascia, Stephen C. Born, Bayan Takizawa, Chuntian Hu
Publikováno v:
Organic Process Research & Development. 25:225-238
Continuous heterogeneous crystallization processes in mixed-suspension mixed-product removal (MSMPR) crystallizers of different configurations (e.g., single-stage cooling, multistage cooling, and m...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19e56efa836f09357f504d56807e8c05
https://doi.org/10.1021/acs.oprd.0c00468
https://doi.org/10.1021/acs.oprd.0c00468
Autor:
Federica Casati, Christopher J. Testa, Xiaochuan Yang, Anjana Ramnath, Ridade Sayin, Stephen C. Born, Paul Hermant, Chuntian Hu, Saptarshi Chattopadhyay, Thomas F. O’Connor, Khrystyna Shvedova, Qinglin Su, Bhakti S. Halkude, Wei Wu, Dongying Erin Shen, Bayan Takizawa, Sukumar Ramanujam, Salvatore Mascia
Publikováno v:
Organic Process Research & Development. 24:2874-2889
The pharmaceutical industry faces multiple challenges (e.g., inefficient manufacturing techniques, quality control issues, and supply chain vulnerabilities) because of its current batch-wise approa...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16fb468d822760a2b0932a632f099552
https://doi.org/10.1021/acs.oprd.0c00383
https://doi.org/10.1021/acs.oprd.0c00383
Autor:
Ridade Sayin, Sukumar Ramanujam, Stephen C. Born, Wei Wu, Salvatore Mascia, Peter E. Sieg, Brianna T. Shores, Bayan Takizawa, Christopher J. Testa, Ana T. Nicosia, Khrystyna Shvedova, Chuntian Hu
Publikováno v:
Organic Process Research & Development. 24:1996-2003
Disadvantages of the traditional batch process have encouraged the pharmaceutical industry to explore continuous manufacturing, including end-to-end approaches, such as integrated continuous manufa...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c33cd2467663e617371a50e5a820a9c9
https://doi.org/10.1021/acs.oprd.0c00092
https://doi.org/10.1021/acs.oprd.0c00092
Autor:
Salvatore Mascia, Sukumar Ramanujam, Christopher J. Testa, Stephen C. Born, Bhakti S. Halkude, Bayan Takizawa, Xiaochuan Yang, Anjana Ramnath, Paul Hermant, Wei Wu, Thomas F. O’Connor, Khrystyna Shvedova, Federica Casati, Ridade Sayin, Chuntian Hu
Publikováno v:
Green Chemistry. 22:4350-4356
Most drugs are still manufactured by time-intensive and cost-inefficient batch processes; however, the pharmaceutical industry is undergoing a transition to continuous processes to benefit from the reduced lead time, cost, and footprint and improved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::006a688e46961376f18e748c12f6b1f3
https://doi.org/10.1039/d0gc01397h
https://doi.org/10.1039/d0gc01397h
Autor:
Bayan Takizawa, Dongying Erin Shen, Salvatore Mascia, Bhakti S. Halkude, Sukumar Ramanujam, Thomas F. O’Connor, Khrystyna Shvedova, Wei Wu, Christopher J. Testa, Stephen C. Born, Xiaochuan Yang, Anjana Ramnath, Federica Casati, Ridade Sayin, Chuntian Hu, Paul Hermant
Publikováno v:
Chemical Communications. 56:1026-1029
We report here a fully automated, end-to-end, integrated continuous manufacturing process for a small-molecule generic medication with built-in quality assurance. The entire process fits into a box of 30.7 m2 modular footprint and a total residence t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94be182d7f897f7e8b0272d41cb639e3
https://doi.org/10.1039/c9cc06945c
https://doi.org/10.1039/c9cc06945c
Autor:
Liyutha Q. Al Ismaili, Bayan Takizawa, Chuntian Hu, Thomas F. O’Connor, Khrystyna Shvedova, Xiaochuan Yang, Sukumar Ramanujam, Anjana Ramnath, Qinglin Su, Brianna T. Shores, Salvatore Mascia, Wei Wu, Ridade Sayin, Stephen C. Born, Christopher J. Testa, Paul Hermant, Rachel A. Derech
Publikováno v:
Reaction Chemistry & Engineering. 5:1950-1962
The continuous reactive crystallization of an active pharmaceutical ingredient (API) in a plug flow reactor (PFR)-continuous stirred tank reactor (CSTR) cascade system with in-line PATs was developed and investigated. Residence time distribution (RTD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab36fa7dd69f964a97954948aec95c44
https://doi.org/10.1039/d0re00216j
https://doi.org/10.1039/d0re00216j
Autor:
Salvatore Mascia, Christopher J. Testa, Brianna T. Shores, Chuntian Hu, Khrystyna Shvedova, Bayan Takizawa, Stephen C. Born, Wei Wu, Saptarshi Chattopadhyay
Publikováno v:
CrystEngComm. 21:5076-5083
Forms I–III and dihydrate carbamazepine (CBZ) were prepared and confirmed by X-ray powder diffraction (XRPD) and differential scanning calorimetry (DSC). Influences of supersaturation (σ), stirring, anti-solvent (H2O), and polymer type on the resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b11643c8da99cf8a07f546761fc43d6
https://doi.org/10.1039/c9ce00908f
https://doi.org/10.1039/c9ce00908f
Publikováno v:
Military medicine. 185(Suppl 1)
There is a tremendous opportunity to modernize the pharmaceutical manufacturing industry—relinquishing outdated machines that have been used for decades, and replacing them with state-of-the-art equipment that reflect more contemporary advanced tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204fc1035a0eb85237a58e87c00c7efc
https://pubmed.ncbi.nlm.nih.gov/32074361
https://pubmed.ncbi.nlm.nih.gov/32074361