Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Salvatore M. Aloj"'
Publikováno v:
Biochimie. 81:287-290
The cholesterol lowering drug lovastatin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, blocks DNA synthesis and proliferation of thyrotropin (TSH) primed FRTL-5 rat thyroid cells. The blockade can be completel
Autor:
Maurizio Bifulco, Leonard D. Kohn, Chiara Laezza, Salvatore M. Aloj, Motoyasu Saji, Bruno Perillo, Idolo Tedesco
Publikováno v:
Journal of Biological Chemistry. 270:15237-15241
3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity and mRNA levels were significantly reduced in FRTL-5 cells transformed with the Kirsten-Moloney sarcoma virus (KiMol); these cells have lost thyrotropin dependence and express high le
Arginine deprivation impairs cell proliferation more strong in cancer than in normal cells; thus, it has been proposed that such an effect could be exploited for cancer therapy. We have compared the effect of arginine deprivation on normal and cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92dc6c79522c6ad3606280c5deeb512e
http://hdl.handle.net/11588/422444
http://hdl.handle.net/11588/422444
Publikováno v:
Biochemical and biophysical research communications. 195(1)
In the epithelial cell line FRT, derived from rat thyroid, extracellular ATP, at a concentration as low as 1 x 10(-7) M, specifically increases cytosolic Ca++ two fold over the basal level of 255 +/- 45 nM. A maximum increase of 5 fold over basal is
Publikováno v:
Journal of inherited metabolic disease. 14(1)
The metabolic basis of X-linked ichthyosis is a deficiency of steroid sulphatase, a microsomal enzyme which removes sulphate groups from sulphated steroids. We report on a carefully controlled group of 15 patients with recessive X-linked ichthyosis,
TSH-induced increases in malic enzyme mRNA levels in FRTL-5 rat thyroid cells are paralleled by increases in malic enzyme activity and are mimicked by 8-bromo-cAMP. Apparent approximately 4 h after TSH challenge and maximal after 16 h, they decline b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb48e306a87bfc9cb11da50a3fd1b91
http://hdl.handle.net/11588/147574
http://hdl.handle.net/11588/147574
Autor:
Idolo Tedesco, Bruno Perillo, Maurizio Bifulco, Corrado Garbi, Chiara Laezza, Alfredo Romano, Salvatore M. Aloj
Publikováno v:
Cell Biology International Reports. 14:103
Autor:
Peter H. Fishman, Lois T. Hunt, George Lee, M. O. Dayhoff, Leonard D. Kohn, Salvatore M. Aloj, Brian R. Mullin, Fred D. Ledley
Publikováno v:
Biochemical and Biophysical Research Communications. 69:852-859
The B chain of cholera toxin and the β subunits of thyrotropin, luteinizing hormone, human chorionic gonadotropin, and follicle-stimulating hormone are shown to have a region of sequence analogy believed to correlate with their ability to bind to re
Autor:
Evelyn F. Grollman, G Lee, Leonard D. Kohn, Salvatore M. Aloj, Eduardo Consiglio, Francesco Beguinot
Publikováno v:
Journal of Biological Chemistry. 254:9040-9049
Phosphatidylinositol, phosphatidylserine, and phosphatidylethanolamine interact with 125I-thyrotropin and inhibit its binding to thyroid plasma membranes; phosphatidylcholine is not similarly effective. The interaction has been monitored by column ch
Publikováno v:
Journal of Endocrinological Investigation. 10:451-458
In the presence of Ro 20-1724, a selective inhibitor of cyclic nucleotide phosphodiesterase, carbamylcholine increases cAMP and cGMP levels in human thyroid cells in primary culture. The increase of cAMP exhibited at concentrations of carbamylcholine