Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Salvatore J. Orlando"'
Autor:
Edward J. Rebar, Jeffrey C. Miller, Adam James Waite, Fyodor D. Urnov, Yolanda Santiago, Edmond Chan, Lin Zhang, Pei-Qi Liu, Aaron Klug, Trevor Collingwood, Philip D. Gregory, Salvatore J. Orlando, Dmitry Guschin, Michael C. Holmes
Gene knockout is the most powerful tool for determining gene function or permanently modifying the phenotypic characteristics of a cell. Existing methods for gene disruption are limited by their efficiency, time to completion, and/or the potential fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d868819ea2f772c91bbf0f7ba5e728
https://europepmc.org/articles/PMC2299223/
https://europepmc.org/articles/PMC2299223/
Publikováno v:
Medical and pediatric oncology. 39(1)
Publikováno v:
Journal of virological methods. 90(2)
A rapid method for the small-scale isolation of SV40 virions and SV40 DNA is presented. CV-1 monkey epithelial cells are transfected with linear SV40 DNA. After the onset of transfection, cells are lysed by several freeze/thaw cycles and virions are
Autor:
Philip D. Gregory, James Li, Erica A. Moehle, Salvatore J. Orlando, Yevgeniy Freyvert, Vivian M. Choi, Gregory J. Cost, Jeffrey C. Miller, Sunita Gopalan, Elizabeth A. Boydston, Michael C. Holmes, Fyodor D. Urnov, Russell Dekelver, Yolanda Santiago, Jacqueline F. Lou
Publikováno v:
Nucleic Acids Research
We previously demonstrated high-frequency, targeted DNA addition mediated by the homology-directed DNA repair pathway. This method uses a zinc-finger nuclease (ZFN) to create a site-specific double-strand break (DSB) that facilitates copying of genet
Autor:
Salvatore J. Orlando, Sharon L. Wenger
Publikováno v:
Clinical Nutrition. 19:467-468
Autor:
Anthony L. Kovatch, Ellen R. Wald, Vincent C. Albo, William Prin, Salvatore J. Orlando, Michael R. Wollman, Carol K. Phebus, Eugene D. Shapiro
Publikováno v:
Pediatrics. 76:754-760
We conducted a randomized, double-blind, placebo-controlled study to evaluate the efficacy of oral trimethoprim/sulfamethoxazole (TMP/SMX) in the prevention of bacterial infections in children with cancer. Sixty-three patients with acute leukemia wer
Publikováno v:
The Journal of Pediatrics. 72:533-536
Summary Attempts were made to detect cytomegaloviruria in 97 children with acute leukemia. Two of these patients (2 per cent) yielded cytomegalovirus, whereas none of 50 control patients yielded cytomegalovirus. Review of autopsy material from 82 leu
Publikováno v:
Medical and pediatric oncology. 12(5)
From a group of 28 patients with biopsy-proven testicular leukemia seen at our institution since 1979, we describe two boys with lymphoid malignancy who, subsequent to 1,800 rad and 2,400 rad testicular radiation, had second overt testicular relapses