Point of care assay for blood aripiprazole concentrations: development, validation and utility

Autor: Matthew Atkins, David Taylor, Ana Catalan, Neville Desouza, Edward Chesney, Thomas J. Reilly, Irina Baburina, Mary Rose Hilaire, Luiz Dratcu, Robert Harland, Salvatore J. Salamone, Philip McGuire

Publikováno v: The British Journal of Psychiatry. :1-5

Background The antipsychotic aripiprazole is often used in the treatment of first-episode psychosis. Measuring aripiprazole blood levels provides an objective measure of treatment adherence, but this currently involves taking a venous blood sample an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3bf9bf67909d246f4b449eb3ed9d79f
https://doi.org/10.1192/bjp.2023.58

Paclitaxel exposure-toxicity analysis reveals a pharmacokinetic determinant for dose-limiting neutropenia in East-Asian solid tumor patients: results from two prospective, phase II studies

Autor: Jinhui Xue, Haipeng He, Zuan Lin, Yuehan Wu, Yuehao Lin, Hongyun Zhao, Salvatore J. Salamone, Yan Huang, Yunpeng Yang, Wenfeng Fang, Yang Zhang, Shaodong Hong, Yuxiang Ma, Li Zhang

Publikováno v: Cancer Chemotherapy and Pharmacology. 90:229-237

The time of a paclitaxel (PTX) concentration remains above 0.05 μM (Tc 0.05) has been associated with PTX-induced adverse effects in Caucasians, while limited studies were reported in Asians. This study was aimed to explore the characteristics of Tc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d69fb46ddeeae13dfd61d040809145
https://doi.org/10.1007/s00280-022-04456-w

Therapeutic drug monitoring in oncology

Autor: Etienne Chatelut, Richard A. Larson, Jennifer H. Martin, William Clarke, Salvatore J. Salamone, Ron H.J. Mathijssen, Alan Kambiz Fotoohi

Publikováno v: European Journal of Cancer. 157:428-440

Although therapeutic drug monitoring (TDM) is an important tool in guiding drug dosing for other areas of medicine including infectious diseases, cardiology, psychiatry and transplant medicine, it has not gained wide acceptance in oncology. For imati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b599d4b470742a2fde9f3fee9062b6
http://www.scopus.com/inward/record.url?scp=85115938008&partnerID=8YFLogxK

New Immunoassays in TDM: Where is the Journey Heading?

Autor: Salvatore J, Salamone, Jodi B, Courtney, William A, Clarke

Publikováno v: Therapeutic drug monitoring.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7105b5f855a1a6c74679fbe661f2c3ae
https://pubmed.ncbi.nlm.nih.gov/36191293

The Alzheimer's Association international guidelines for handling of cerebrospinal fluid for routine clinical measurements of amyloid β and tau

Autor: Charlotte E. Teunissen, Christopher Traynham, Kaj Blennow, Veronika Corradini, Oskar Hansson, John Lawson, Christopher J. Weber, Hugo Vanderstichele, Laura Nisenbaum, Rianne Esquivel, Manu Vandijck, Robert M. Umek, Maria C. Carrillo, Nathalie Le Bastard, Richard Batrla, Simone Wahl, Henrik Zetterberg, Britta Brix, Salvatore J. Salamone, Christina Hall, Sandra Rutz, José Luis Molinuevo, Rebecca M. Edelmayer

Publikováno v: Hansson, O, Batrla, R, Brix, B, Carrillo, M C, Corradini, V, Edelmayer, R M, Esquivel, R N, Hall, C, Lawson, J, Bastard, N L, Molinuevo, J L, Nisenbaum, L K, Rutz, S, Salamone, S J, Teunissen, C E, Traynham, C, Umek, R M, Vanderstichele, H, Vandijck, M, Wahl, S, Weber, C J, Zetterberg, H & Blennow, K 2021, ' The Alzheimer's Association international guidelines for handling of cerebrospinal fluid for routine clinical measurements of amyloid β and tau ', Alzheimer's and Dementia, vol. 17, no. 9, pp. 1575-1582 . https://doi.org/10.1002/alz.12316
Alzheimer's and Dementia, 17(9), 1575-1582. Elsevier

The core cerebrospinal fluid (CSF) Alzheimer's disease (AD) biomarkers amyloid beta (Aβ42 and Aβ40), total tau, and phosphorylated tau, have been extensively clinically validated, with very high diagnostic performance for AD, including the early ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70bdc00bed6e5bab3fd2b5650f0cee4
https://research.vumc.nl/en/publications/9db99749-781f-4087-82d3-72f3cfab423f