The G-protein-coupled receptor APJ is expressed in the second heart field and regulates Cerberus–Baf60c axis in embryonic stem cell cardiomyogenesis

Autor: Giovanna L. Liguori, Salvatore Iaconis, Gennaro Andolfi, Gilda Cobellis, Cristina D'Aniello, Alessandro Fiorenzano, Annalisa Fico, Gabriella Minchiotti

Publikováno v: Cardiovascular research (2013). doi:10.1093/cvr/cvt166
info:cnr-pdr/source/autori:D'Aniello C, Fiorenzano A, Iaconis S, Liguori GL, Andolfi G, Cobellis G, Fico A, Minchiotti G./titolo:The G protein coupled receptor Apj is expressed in the second heart field and regulates Cerberus-Baf60C axis in embryonic stem cell cardiomyogenesis./doi:10.1093%2Fcvr%2Fcvt166/rivista:Cardiovascular research/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume
Cardiovascular Research; Vol 100

Aims Mammalian cardiomyogenesis occurs through a multistep process that requires a complex network of tightly regulated extracellular signals, which integrate with the genetic and epigenetic machinery to maintain, expand, and regulate the differentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ae5e0fcff3f8328853f147cb4e969d
https://doi.org/10.1093/cvr/cvt166

Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin

Autor: Philippos Mourikis, Shahragim Tajbakhsh, Katrien De Bock, Giulio Cossu, Giovanna L. Liguori, Peter Carmeliet, Enza Lonardo, Ann Bouché, Thierry Touvier, Silvia Brunelli, Gennaro Andolfi, Peggy Lafuste, Salvatore Iaconis, Gabriella Minchiotti, Ombretta Guardiola, Michael M. Shen

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (47), pp.E3231-E3240. ⟨10.1073/pnas.1204017109⟩
Proceedings of the National Academy of Sciences; Vol 109
Proceedings of the National Academy of Sciences of the United States of America 109(47) (2012): E2331–E2340. doi:10.1073/pnas.1204017109
info:cnr-pdr/source/autori:Guardiola O, Lafuste P, Brunelli S, Iaconis S, Touvier T, Mourikis P, De Bock K, Lonardo E, Andolfi G, Bouché A, Liguori GL, Shen MM, Tajbakhsh S, Cossu G, Carmeliet P, Minchiotti G./titolo:Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin./doi:10.1073%2Fpnas.1204017109/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2012/pagina_da:E2331/pagina_a:E2340/intervallo_pagine:E2331–E2340/volume:109(47)

Skeletal muscle regeneration mainly depends on satellite cells, a population of resident muscle stem cells. However, our understanding of the molecular mechanisms underlying satellite cell activation is still largely undefined. Here, we show that Cri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88148e2c0c5d55122b49b7c31178210e
https://pubmed.ncbi.nlm.nih.gov/23129614

A novel role for Cripto in satellite cells and post-natal skeletal muscle regeneration through modulation of TGFB family signaling pathways

Autor: Ombretta Guardiola, Peggy Lafuste, Silvia Brunelli, Salvatore Iaconis, Giulio Cossu, Peter Carmeliet, Gabriella Minchiotti

Publikováno v: TOPEA Meeting, Barcellona, 2010
info:cnr-pdr/source/autori:Ombretta Guardiola, Peggy Lafuste, Silvia Brunelli, Salvatore Iaconis, Giulio Cossu, Peter Carmeliet and Gabriella Minchiotti/congresso_nome:TOPEA Meeting/congresso_luogo:Barcellona/congresso_data:2010/anno:2010/pagina_da:/pagina_a:/intervallo_pagine
info:cnr-pdr/source/autori:Ombretta Guardiola, Peggy Lafuste, Silvia Brunelli, Salvatore Iaconis, Giulio Cossu, Peter Carmeliet and Gabriella Minchiotti/congresso_nome:TOPEA Meeting, Barcellona/congresso_luogo:/congresso_data:2010/anno:2010/pagina_da:/pagina_a:/intervallo_pagine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6062c92703a7addc4fa55f5165839fe1
https://publications.cnr.it/doc/110092

G protein-coupled receptor APJ and its ligand apelin act downstream of Cripto to specify embryonic stem cells toward the cardiac lineage through extracellular signal-regulated kinase/p70S6 kinase signaling pathway

Autor: Giovanna L. Liguori, Peter Carmeliet, Monica Autiero, Ombretta Guardiola, Anna Maria Liguoro, Salvatore Iaconis, Gabriella Minchiotti, Cristina D'Aniello, Enza Lonardo

Publikováno v: Circulation research 105 (2009): 231–238. doi:10.1161/CIRCRESAHA.109.201186
info:cnr-pdr/source/autori:D'Aniello C.; Lonardo E..; Iaconis S; Guardiola O.; Liguoro A.M.; Liguori G.L.; Autiero M.; Carmeliet P.; Minchiotti G./titolo:G protein-coupled receptor APJ and its ligand apelin act downstream of Cripto to specify embryonic stem cells toward the cardiac lineage through extracellular signal-regulated kinase%2Fp70S6 kinase signaling pathway/doi:10.1161%2FCIRCRESAHA.109.201186/rivista:Circulation research/anno:2009/pagina_da:231/pagina_a:238/intervallo_pagine:231–238/volume:105

Rationale: Pluripotent stem cells represent a powerful model system to study the early steps of cardiac specification for which the molecular control is largely unknown. The EGF-CFC (epidermal growth factor-Cripto/FRL-1/Cryptic) Cripto protein is ess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c553586cf98d0cd79c7e5bd2ed645f7f