Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Salvatore Demartis"'
Autor:
Lorenzo Arrico, Carmine Stolfi, Irene Marafini, Giovanni Monteleone, Salvatore Demartis, Salvatore Bellinvia, Francesca Viti, Marie McNulty, Irene Cabani, Anita Falezza, Lorenzo Di Bari
Mongersen is a 21-mer antisense oligonucleotide designed to downregulate Mothers against decapentaplegic homolog 7 (SMAD7) expression to treat Crohn's disease. Mongersen was manufactured in numerous batches at different scales during several years of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c7c876892c8daf131772f584081842
http://hdl.handle.net/2108/294116
http://hdl.handle.net/2108/294116
Publikováno v:
Tetrahedron. 56:8375-8382
Reduction of symmetrical intramolecular diarylmethyl ethers (3a and 8a) and amines (3b and 8b) with alkali metals in THF allows the generation of unsymmetrical oxy- or amino-functionalised arylmethyl organometallics. Such intermediates were successfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eea629dd5e380637be21ec2743ca09ae
https://doi.org/10.1016/s0040-4020(00)00783-3
https://doi.org/10.1016/s0040-4020(00)00783-3
Autor:
Dario Neri, Paolo Neri, Greg Winter, Leonardo Giovannoni, Francesca Viti, Luisa Lozzi, Adrian Huber, Salvatore Demartis
Publikováno v:
Journal of Molecular Biology. 286:617-633
We have aimed at developing a general methodology for the isolation of enzymatic activities from large repertoires of protein displayed on the surface of a filamentous phage. When selecting for protein binders by phage display, phage particles with s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c8d62ea0990d985fbcc5d1142aa44ff
https://doi.org/10.1006/jmbi.1998.2476
https://doi.org/10.1006/jmbi.1998.2476
Publikováno v:
Tetrahedron Letters. 36:8123-8126
Reductive cleavage of phthalun, 1a, with Li metal in the presence of a catalytic amount of naphthalene leads to the formation of a stable aromatic dilithium compound. The adducts of the latter with CO2, aldehydes or ketones undergo ring closure to is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a8ca0c5b53ea3f692a246475de46662
https://doi.org/10.1016/0040-4039(95)01692-b
https://doi.org/10.1016/0040-4039(95)01692-b
Publikováno v:
ChemInform. 26
Stable α-methoxy arylmethyl carbanions can be generated by metalation of arylmethyl methyl ethers, 1 , with n -BuLi in THF at −40 °C, avoiding Wittig rearrangement to the corresponding alkoxides 2 . Reaction of these carbanions with various elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eb5fa5056015a6e765e909db669397c
https://doi.org/10.1002/chin.199546103
https://doi.org/10.1002/chin.199546103
Publikováno v:
ChemInform. 27
Reductive cleavage of phthalun, 1a, with Li metal in the presence of a catalytic amount of naphthalene leads to the formation of a stable aromatic dilithium compound. The adducts of the latter with CO2, aldehydes or ketones undergo ring closure to is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac8e95c0d4ee92376511750b335f215b
https://doi.org/10.1002/chin.199607155
https://doi.org/10.1002/chin.199607155
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eebcec70e156cc101083fbd4b90dba5
https://doi.org/10.1002/chin.199649053
https://doi.org/10.1002/chin.199649053
Publikováno v:
European journal of nuclear medicine. 28(4)
Angiogenesis is a characteristic feature of many aggressive tumours and other disorders. Antibodies capable of binding to new blood vessels, but not to mature vessels, could be used as selective targeting agents for immunoscintigraphic and radioimmun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ae9941bebd9915cd7979ce710d5038
https://pubmed.ncbi.nlm.nih.gov/11357506
https://pubmed.ncbi.nlm.nih.gov/11357506
Publikováno v:
ChemInform. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::822c10c0c99c494f24f39813ed106d53
https://doi.org/10.1002/chin.200109038
https://doi.org/10.1002/chin.200109038
Autor:
Salvatore Demartis, Samu Melkko, Paolo Neri, Christian Heinis, Adrian Huber, Julian Bertschinger, Dario Neri, Luisa Lozzi
Publikováno v:
Scopus-Elsevier
Protein Engineering, 14 (12)
Protein Engineering, 14 (12)
Protein Engineering, 14 (12)
ISSN:0269-2139
ISSN:1460-213X
ISSN:0269-2139
ISSN:1460-213X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0cc9cbb33f6492b33c77eb86179ba0
http://hdl.handle.net/11365/18831
http://hdl.handle.net/11365/18831