Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Salvatore, Valvo"'
Autor:
Mike B. Barnkob, Yale S. Michaels, Violaine André, Philip S. Macklin, Uzi Gileadi, Salvatore Valvo, Margarida Rei, Corinna Kulicke, Ji-Li Chen, Vitul Jain, Victoria K. Woodcock, Huw Colin-York, Andreas V. Hadjinicolaou, Youxin Kong, Viveka Mayya, Julie M. Mazet, Gracie-Jennah Mead, Joshua A. Bull, Pramila Rijal, Christopher W. Pugh, Alain R. Townsend, Audrey Gérard, Lars R. Olsen, Marco Fritzsche, Tudor A. Fulga, Michael L. Dustin, E. Yvonne Jones, Vincenzo Cerundolo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Semaphorin-3A (SEMA3A) functions as a chemorepulsive signal during development and can affect T cells by altering their filamentous actin (F-actin) cytoskeleton. The exact extent of these effects on tumour-specific T cells are not completely
Externí odkaz:
https://doaj.org/article/0037fd20318049ccb1e0d08f25e77331
Autor:
Mike B. Barnkob, Yale S. Michaels, Violaine André, Philip S. Macklin, Uzi Gileadi, Salvatore Valvo, Margarida Rei, Corinna Kulicke, Ji-Li Chen, Vitul Jain, Victoria K. Woodcock, Huw Colin-York, Andreas V. Hadjinicolaou, Youxin Kong, Viveka Mayya, Julie M. Mazet, Gracie-Jennah Mead, Joshua A. Bull, Pramila Rijal, Christopher W. Pugh, Alain R. Townsend, Audrey Gérard, Lars R. Olsen, Marco Fritzsche, Tudor A. Fulga, Michael L. Dustin, E. Yvonne Jones, Vincenzo Cerundolo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/c91684507e624290b137868f21bb7e7e
Autor:
Pablo F. Céspedes, Ashwin Jainarayanan, Lola Fernández-Messina, Salvatore Valvo, David G. Saliba, Elke Kurz, Audun Kvalvaag, Lina Chen, Charity Ganskow, Huw Colin-York, Marco Fritzsche, Yanchun Peng, Tao Dong, Errin Johnson, Jesús A. Siller-Farfán, Omer Dushek, Erdinc Sezgin, Ben Peacock, Alice Law, Dimitri Aubert, Simon Engledow, Moustafa Attar, Svenja Hester, Roman Fischer, Francisco Sánchez-Madrid, Michael L. Dustin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
T cells communicate with antigen-presenting cells (APC) via the signaling crosstalk at the immunological synapse (IS). Here the authors use bead-supported lipid bilayers as synthetic APCs to find that trans-synaptic vesicles produced by T cells in th
Externí odkaz:
https://doaj.org/article/bf36826120af49d29b1ddc87ef30f8f6
Autor:
Ashwin K. Jainarayanan, Jesusa Capera, Pablo F. Céspedes, Mariana Conceição, Mirudula Elanchezhian, Tom Thomas, Scott Bonner, Salvatore Valvo, Elke Kurz, Ranjeet Singh Mahla, Georgina Berridge, Svenja Hester, Roman Fischer, Lynn B. Dustin, Matthew J. A. Wood, Michael L. Dustin
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 3, Pp n/a-n/a (2023)
Abstract CD8+ T lymphocytes play vital roles in killing infected or deranged host cells, recruiting innate immune cells, and regulating other aspects of immune responses. Like any other cell, CD8+ T cells also produce extracellular particles. These i
Externí odkaz:
https://doaj.org/article/32d16e0396074aa09d2b070143e7e28d
Autor:
Anastasios Siokis, Philippe A. Robert, Philippos Demetriou, Audun Kvalvaag, Salvatore Valvo, Viveka Mayya, Michael L. Dustin, Michael Meyer-Hermann
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103100- (2021)
Summary: Small immunoglobulin superfamily (sIGSF) adhesion complexes form a corolla of microdomains around an integrin ring and secretory core during immunological synapse (IS) formation. The corolla recruits and retains major costimulatory/checkpoin
Externí odkaz:
https://doaj.org/article/1961a091187641ce8d77cb84243f0b4a
Autor:
Chiara Cassioli, Stefan Balint, Ewoud B. Compeer, James H. Felce, Alessandra Gamberucci, Chiara Della Bella, Suet Ling Felce, Jlenia Brunetti, Salvatore Valvo, Daniela Pende, Mario M. D’Elios, Lorenzo Moretta, Michael L. Dustin, Cosima T. Baldari
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The Jurkat E6.1 clone has been extensively used as a powerful tool for the genetic and biochemical dissection of the TCR signaling pathway. More recently, these cells have been exploited in imaging studies to identify key players in immunological syn
Externí odkaz:
https://doaj.org/article/88aac67970b744909330134c6d3a8da4
Autor:
David G Saliba, Pablo F Céspedes-Donoso, Štefan Bálint, Ewoud B Compeer, Kseniya Korobchevskaya, Salvatore Valvo, Viveka Mayya, Audun Kvalvaag, Yanchun Peng, Tao Dong, Maria-Laura Tognoli, Eric O'Neill, Sarah Bonham, Roman Fischer, Benedikt M Kessler, Michael L Dustin
Publikováno v:
eLife, Vol 8 (2019)
Planar supported lipid bilayers (PSLB) presenting T cell receptor (TCR) ligands and ICAM-1 induce budding of extracellular microvesicles enriched in functional TCR, defined here as synaptic ectosomes (SE), from helper T cells. SE bind peptide-MHC dir
Externí odkaz:
https://doaj.org/article/40ca633e770d440aa82c9062daa1f80b
Autor:
Ashwin K. Jainarayanan, Jesusa Capera, Pablo F. Céspedes, Mariana Conceição, Mirudula Elanchezhian, Tom Thomas, Scott Bonner, Salvatore Valvo, Elke Kurz, Ranjeet Singh Mahla, Georgina Berridge, Svenja Hester, Roman Fischer, Lynn B. Dustin, Matthew J. A. Wood, Michael L. Dustin
Publikováno v:
Journal of Extracellular Biology. 2
CD8+ T lymphocytes play vital roles in killing infected or deranged host cells, recruiting innate immune cells, and regulating other aspects of immune responses. Like any other cell, CD8+ T cells also produce extracellular particles. These include ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290fa9d29a560ca4a8a4b1da0740e678
https://doi.org/10.1002/jex2.74
https://doi.org/10.1002/jex2.74
Autor:
Audun Kvalvaag, Pablo F Céspedes, Salvatore Valvo, David G Saliba, Elke Kurz, Kseniya Korobchevskaya, Michael L Dustin
Ligation of the T cell receptor (TCR) to peptide-MHC complexes initiates signaling leading to T cell activation. Regulation of T cell responses also requires mechanisms to stop this signaling and to downregulate surface expression of the receptor. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8c05f9dfcb2c1594efdd985e5f88962
https://doi.org/10.1101/2022.02.02.478780
https://doi.org/10.1101/2022.02.02.478780
Understanding the spatial and functional link between the IL-2R and TCR at the immunological synapse
Autor:
Jesusa Capera-Aragones, Lina Chen, Salvatore Valvo, Anish Suri, Raymond Moniz, Michael L. Dustin
Publikováno v:
Biophysical Journal. 122:510a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b128c4839b6649aba176afef9281f69
https://doi.org/10.1016/j.bpj.2022.11.2717
https://doi.org/10.1016/j.bpj.2022.11.2717