Zobrazeno 1 - 10
of 398
pro vyhledávání: '"Salvatore, Russo"'
Autor:
Michaela Feodoroff, Firas Hamdan, Gabriella Antignani, Sara Feola, Manlio Fusciello, Salvatore Russo, Jacopo Chiaro, Katja Välimäki, Teijo Pellinen, Rui M. Branca, Janne Lehtiö, Federica D´alessio, Paolo Bottega, Virpi Stigzelius, Janita Sandberg, Jonna Clancy, Jukka Partanen, Minna Malmstedt, Antti Rannikko, Vilja Pietiäinen, Mikaela Grönholm, Vincenzo Cerullo
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Immunotherapy has emerged as a promising approach for cancer treatment, with oncolytic adenoviruses showing power as immunotherapeutic agents. In this study, we investigated the immunotherapeutic potential of an adenovirus construct expressing CXCL9,
Externí odkaz:
https://doaj.org/article/9f9b01d5a4b141ec9e694bed2adb86b2
Autor:
Sari Pesonen, Sara Feola, Manlio Fusciello, Vincenzo Cerullo, Firas Hamdan, Jacopo Chiaro, Michaela Feodoroff, Gabriella Antignani, Salvatore Russo, Jeanette Leusen, Mikaela Grönholm, Federica D'Alessio, Riikka Mölsä, Virpi Stigzelius, Paolo Bottega
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background Cancer immunotherapy relies on using the immune system to recognize and eradicate cancer cells. Adaptive immunity, which consists of mainly antigen-specific cytotoxic T cells, plays a pivotal role in controlling cancer progression. However
Externí odkaz:
https://doaj.org/article/0b92fefeeea843e8b25b72efaf0979c0
Autor:
Jacopo Chiaro, Gabriella Antignani, Sara Feola, Michaela Feodoroff, Beatriz Martins, Hanne Cojoc, Salvatore Russo, Manlio Fusciello, Firas Hamdan, Valentina Ferrari, Daniele Ciampi, Ilkka Ilonen, Jari Räsänen, Mikko Mäyränpää, Jukka Partanen, Satu Koskela, Jarno Honkanen, Jussi Halonen, Lukasz Kuryk, Maria Rescigno, Mikaela Grönholm, Rui M. Branca, Janne Lehtiö, Vincenzo Cerullo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Malignant pleural mesothelioma (MPM) is an aggressive tumor with a poor prognosis. As the available therapeutic options show a lack of efficacy, novel therapeutic strategies are urgently needed. Given its T-cell infiltration, we hypothesized
Externí odkaz:
https://doaj.org/article/6e1ca484af774f7185adf7528cf6e262
Autor:
Firas Hamdan, Michaela Feodoroff, Salvatore Russo, Manlio Fusciello, Sara Feola, Jacopo Chiaro, Gabriella Antignani, Francesca Greco, Jeanette Leusen, Erkko Ylösmäki, Mikaela Grönholm, Vincenzo Cerullo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 28, Iss , Pp 264-276 (2023)
Immune checkpoint inhibitors have clinical success in prolonging the life of many cancer patients. However, only a minority of patients benefit from such therapy, calling for further improvements. Currently, most PD-L1 checkpoint inhibitors in the cl
Externí odkaz:
https://doaj.org/article/c101489aa59748e7965fdcfb82860f67
A novel cancer vaccine for melanoma based on an approved vaccine against measles, mumps, and rubella
Autor:
Manlio Fusciello, Erkko Ylösmäki, Sara Feola, Arttu Uoti, Beatriz Martins, Karri Aalto, Firas Hamdan, Jacopo Chiaro, Salvatore Russo, Tapani Viitala, Vincenzo Cerullo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 25, Iss , Pp 137-145 (2022)
Common vaccines for infectious diseases have been repurposed as cancer immunotherapies. The intratumoral administration of these repurposed vaccines can induce immune cell infiltration into the treated tumor. Here, we have used an approved trivalent
Externí odkaz:
https://doaj.org/article/38eb34c95a1041b2ad52990b03671885
Autor:
Santhosh Thavarajasingam, Mahmoud El-Khatib, Kalyan Vemulapalli, Hector A. Sinzinkayo Iradukunda, Sajeenth Vishnu J, Robin Borchert, Salvatore Russo, Per K. Eide
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 102293- (2023)
Externí odkaz:
https://doaj.org/article/b0d6971954ad42fe8dc3ad9a24651a08
This volume aims to shed light on how public service value is identified, managed, measured and reported. The concept of public value has been increasingly associated with the process of modernisation and in recent years the debate has shifted away f
Autor:
Luca Mincigrucci, Marco Civera, Erica Lenticchia, Rosario Ceravolo, Michele Rosano, Salvatore Russo
Publikováno v:
Materials, Vol 16, Iss 14, p 4908 (2023)
Fibre-reinforced polymer composites in general, and especially glass fibre-reinforced polymer (GFRP), have increasingly been used in recent decades in construction. The advantages of GFRP as an alternative construction material are its high strength-
Externí odkaz:
https://doaj.org/article/cdbf6df60c65434ea4790abb8c3eeecb
Autor:
Sara Feola, Salvatore Russo, Beatriz Martins, Alessandra Lopes, Gaëlle Vandermeulen, Vinciane Fluhler, Camilla De Giorgi, Manlio Fusciello, Sari Pesonen, Erkko Ylösmäki, Gabriella Antignani, Jacopo Chiaro, Firas Hamdan, Michaela Feodoroff, Mikaela Grönholm, Vincenzo Cerullo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Oncolytic Viruses (OVs) work through two main mechanisms of action: the direct lysis of the virus-infected cancer cells and the release of tumor antigens as a result of the viral burst. In this sc.enario, the OVs act as in situ cancer vaccines, since
Externí odkaz:
https://doaj.org/article/77e488c599dd49e8bc1997a7c98a0197
A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines
Autor:
Sara Feola, Jacopo Chiaro, Beatriz Martins, Salvatore Russo, Manlio Fusciello, Erkko Ylösmäki, Chiara Bonini, Eliana Ruggiero, Firas Hamdan, Michaela Feodoroff, Gabriella Antignani, Tapani Viitala, Sari Pesonen, Mikaela Grönholm, Rui MM Branca, Janne Lehtiö, Vincenzo Cerullo
Publikováno v:
eLife, Vol 11 (2022)
Besides the isolation and identification of major histocompatibility complex I-restricted peptides from the surface of cancer cells, one of the challenges is eliciting an effective antitumor CD8+ T-cell-mediated response as part of therapeutic cancer
Externí odkaz:
https://doaj.org/article/85126efc79c44ba3a737f661bff8e40b