Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Salvador Soriano"'
Publikováno v:
Brain Sciences, Vol 14, Iss 6, p 601 (2024)
Cerebral amyloid angiopathy is characterized by a weakening of the small- and medium-sized cerebral arteries, as their smooth muscle cells are progressively replaced with acellular amyloid β, increasing vessel fragility and vulnerability to microhem
Externí odkaz:
https://doaj.org/article/485fd87df7834eee8d4c93ab2a77cc89
Autor:
Samuel D. Shin, Alexandra Shin, Karina Mayagoitia, Lorraine Siebold, Marsilio Rubini, Christopher G. Wilson, Denise L. Bellinger, Salvador Soriano
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract Background Niemann-Pick disease type C (NPC) is a progressive neurodegenerative condition that results in early fatality. NPC is inherited in an autosomal recessive pattern from mutations in NPC1 or NPC2 genes. The etiology of NPC is poorly
Externí odkaz:
https://doaj.org/article/c8c3e9aeac1049718d2c22f997717915
Publikováno v:
Neurobiology of Disease, Vol 42, Iss 3, Pp 349-359 (2011)
Niemann–Pick type C disease (NPC) is a lysosomal storage disorder which, at the cellular level, shows amyloid Aβ and tau pathologies comparable to those seen in the AD brain. Here, we have investigated, in a mouse model of NPC, the impact of remov
Externí odkaz:
https://doaj.org/article/94315fab4f0d4057b1eee13e22e32540
Publikováno v:
Zdravniški Vestnik, Vol 77, Iss SUPPII (2008)
Differentiated neurons display specific biochemical, physiological and morphological properties that apparently prevent them from further cell division. Nevertheless, expression ofcell cycle modulators persists after neuronal differentiation and is u
Externí odkaz:
https://doaj.org/article/614bbdec3e0f489991e98675f9995170
Autor:
Andrew J. Tolan, Samuel D. Shin, Denise L. Bellinger, Johnny D. Figueroa, Karina Mayagoitia, Salvador Soriano, Jesus A. Menchaca, Abu Shufian Ishtiaq Ahmed, Shohali Shammi, Christopher G. Wilson
Publikováno v:
Physiol Behav
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to memory loss and is often accompanied by increased anxiety. Although AD is a heterogeneous disease, dysregulation of inflammatory pathways is a consistent event. Intere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ff2b42cdd77da7f5b87a5c5c4f1890
https://europepmc.org/articles/PMC9020203/
https://europepmc.org/articles/PMC9020203/
Autor:
Denise L. Bellinger, Alexandra Shin, Salvador Soriano, Karina Mayagoitia, Christopher G. Wilson, Samuel Dong Kyu Shin
Publikováno v:
Neuroscience Letters. 706:43-50
Niemann-Pick disease type C (NPC) is a fatal neurodegenerative condition with no FDA-approved therapy. Previous studies demonstrated that neuroinflammation is an early pathologic event and a disease modifier of NPC, affecting symptomatic onset and ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08771154247ddd8c164e460778e1d48c
https://doi.org/10.1016/j.neulet.2019.05.005
https://doi.org/10.1016/j.neulet.2019.05.005
Autor:
Sergio Romeo López Alonso, Ana I. Martínez García, Susana Martin Caravante, Ignacio Salvador Soriano Ruiz, Irene Martínez Rios, María Isabel Moreno Moreno
Publikováno v:
Medicina Paliativa.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f66022dcc273bc46817c95e4f325709d
https://doi.org/10.20986/medpal.2020.1109/2019
https://doi.org/10.20986/medpal.2020.1109/2019
Autor:
Denise L. Bellinger, Salvador Soriano, Sam D. Shin, Marsilio Rubini, Johnny D. Figueroa, Lorraine Siebold, Christopher G. Wilson, Karina Mayagoitia
Publikováno v:
Behavioural brain research. 393
Alzheimer’s disease (AD) is a neurodegenerative condition associated with loss of memory function, depression and anxiety. The etiology of AD is poorly understood, but both cholesterol dyshomeostasis and dysregulation of the immune system are contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e94760e125271a1633afa5b503a6a8d
https://pubmed.ncbi.nlm.nih.gov/32585301
https://pubmed.ncbi.nlm.nih.gov/32585301
Autor:
Alexandra Shin, Karina Mayagoitia, Denise L. Bellinger, Marsilio Rubini, Lorraine Siebold, Christopher G. Wilson, Samuel D. Shin, Salvador Soriano
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-15 (2019)
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-15 (2019)
Background Niemann-Pick disease type C (NPC) is a progressive neurodegenerative condition that results in early fatality. NPC is inherited in an autosomal recessive pattern from mutations in NPC1 or NPC2 genes. The etiology of NPC is poorly defined.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee5d490ac0efcf9cf55160e67d324eb
https://pubmed.ncbi.nlm.nih.gov/31847862
https://pubmed.ncbi.nlm.nih.gov/31847862
Autor:
Othman Ghribi, Salvador Soriano, Wolff M. Kirsch, John David Jeppson, Harry V. Vinters, Nicholas Sanchez, Brendan Gongol, Karina Mayagoitia, Samuel Shin, Traci L. Marin, Christopher G. Wilson
Publikováno v:
Scientific reports, vol 7, iss 1
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
The function of the amyloid precursor protein (APP) in brain health remains unclear. This study elucidated a novel cytoprotective signaling pathway initiated by the APP transcriptionally active intracellular domain (AICD) in response to 27-hydroxycho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11efb290041447dfb712e3a0f45794b8
https://escholarship.org/uc/item/4sz093nr
https://escholarship.org/uc/item/4sz093nr