Glutathione and a Pool of Metabolites Partly Related to Oxidative Stress Are Associated with Low and High Myopia in an Altered Bioenergetic Environment

Autor: Salvador Mérida, Amparo Návea, Carmen Desco, Bernardo Celda, Mercedes Pardo-Tendero, José Manuel Morales-Tatay, Francisco Bosch-Morell

Publikováno v: Antioxidants, Vol 13, Iss 5, p 539 (2024)

Oxidative stress forms part of the molecular basis contributing to the development and manifestation of myopia, a refractive error with associated pathology that is increasingly prevalent worldwide and that subsequently leads to an upsurge in degener

Externí odkaz: https://doaj.org/article/8a8591693be54ee9a7b9e89f62d33217

Lipid Peroxidation in Subretinal Fluid: Some Light on the Prognosis Factors

Autor: Francisco Bosch-Morell, Enrique García-Gen, Salvador Mérida, Mariola Penadés, Carmen Desco, Amparo Navea

Publikováno v: Biomolecules, Vol 11, Iss 4, p 514 (2021)

The aim of this study was to identify a relation between the clinical characteristics and differences in lipid peroxidation in the subretinal fluid (SRF) of rhegmatogenous retinal detached patients by malondialdehyde (MDA) quantification. We collecte

Externí odkaz: https://doaj.org/article/51227cf54c34464c90df78dbf4ea83ee

Bevacizumab Diminishes Inflammation in an Acute Endotoxin-Induced Uveitis Model

Autor: Salvador Mérida, María Sancho-Tello, Inmaculada Almansa, Carmen Desco, Cristina Peris, Mari-Luz Moreno, Vincent M. Villar, Amparo Navea, Francisco Bosch-Morell

Publikováno v: Frontiers in Pharmacology, Vol 9 (2018)

Introduction: Uveitis is an eye disease characterized by inflammation of the uvea and an early and exhaustive diagnosis is essential for its treatment. The aim of our study is to assess the potential toxicity and anti-inflammatory efficacy of Bevaciz

Externí odkaz: https://doaj.org/article/493ea9e1a2cc4f9dba0e545137437643

Macrophages and Uveitis in Experimental Animal Models

Autor: Salvador Mérida, Elena Palacios, Amparo Navea, Francisco Bosch-Morell

Publikováno v: Mediators of Inflammation, Vol 2015 (2015)

Resident and infiltrated macrophages play relevant roles in uveitis as effectors of innate immunity and inductors of acquired immunity. They are major effectors of tissue damage in uveitis and are also considered to be potent antigen-presenting cells

Externí odkaz: https://doaj.org/article/46dade6ce78e4c028097ad18bea6bccc

High Myopia and the Complement System: Factor H in Myopic Maculopathy

Autor: Rafael Araujo-Miranda, Mariola Penadés, Salvador Mérida, Carmen Desco, Francisco Bosch-Morell, Amparo Navea, Enrique García-Gen

Publikováno v: Journal of Clinical Medicine, Vol 10, Iss 2600, p 2600 (2021)
CEU Repositorio Institucional
Fundación Universitaria San Pablo CEU (FUSPCEU)
Journal of Clinical Medicine
Volume 10
Issue 12

High myopia (HM) is both a medical problem and refractive error of the eye owing to excessive eyeball length, which progressively makes eye tissue atrophic, and is one of the main causes for diminishing visual acuity in developed countries. Despite i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001e8bc80f1d24c9a97e6c785beb3fd7
https://www.mdpi.com/2077-0383/10/12/2600