Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Salvador Espín"'
Autor:
David Zaragoza-Huesca, Maria Carmen Rodenas, Julia Peñas-Martínez, Irene Pardo-Sánchez, Jorge Peña-García, Salvador Espín, Guillermo Ricote, Andrés Nieto, Francisco García-Molina, Vicente Vicente, Maria Luisa Lozano, Alberto Carmona-Bayonas, Victoriano Mulero, Horacio Pérez-Sánchez, Irene Martínez-Martínez
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115814- (2023)
Recently, our group identified serine-protease hepsin from primary tumor as a biomarker of metastasis and thrombosis in patients with localized colorectal cancer. We described hepsin promotes invasion and thrombin generation of colorectal cancer cell
Externí odkaz:
https://doaj.org/article/3c1e41ad623449c197e68a3ce72e012a
Autor:
Maria Carmen Rodenas, Julia Peñas-Martínez, Irene Pardo-Sánchez, David Zaragoza-Huesca, Carmen Ortega-Sabater, Jorge Peña-García, Salvador Espín, Guillermo Ricote, Sofía Montenegro, Francisco Ayala-De La Peña, Ginés Luengo-Gil, Andrés Nieto, Francisco García-Molina, Vicente Vicente, Francesco Bernardi, María Luisa Lozano, Victoriano Mulero, Horacio Pérez-Sánchez, Alberto Carmona-Bayonas, Irene Martínez-Martínez
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: Hepsin is a type II transmembrane serine protease and its expression has been linked to greater tumorigenicity and worse prognosis in different tumors. Recently, our group demonstrated that high hepsin levels from primary tumor were ass
Externí odkaz:
https://doaj.org/article/0a0bec65f1084dbb942a08af8b945209
Autor:
David Zaragoza-Huesca, Carlos Martínez-Cortés, Antonio Jesús Banegas-Luna, Alfonso Pérez-Garrido, Josefina María Vegara-Meseguer, Julia Peñas-Martínez, Maria Carmen Rodenas, Salvador Espín, Horacio Pérez-Sánchez, Irene Martínez-Martínez
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2796 (2022)
The endogenous protease furin is a key protein in many different diseases, such as cancer and infections. For this reason, a wide range of studies has focused on targeting furin from a therapeutic point of view. Our main objective consisted of identi
Externí odkaz:
https://doaj.org/article/d877d0f8144a498faa124e2271118058
Autor:
Julia Peñas-Martínez, Ginés Luengo-Gil, Salvador Espín, Nataliya Bohdan, Carmen Ortega-Sabater, Maria Carmen Ródenas, David Zaragoza-Huesca, María José López-Andreo, Carme Plasencia, Vicente Vicente, Alberto Carmona-Bayonas, Irene Martínez-Martínez
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 523 (2021)
Antithrombin, the main physiological inhibitor of the coagulation cascade, exerts anti-tumor effects on glioblastoma multiforme cells. Antithrombin has different conformations: native, heparin-activated, prelatent, latent, and cleaved. The prelatent
Externí odkaz:
https://doaj.org/article/c64fa4755e314cc7b1a0e322be8cebb6
Autor:
Sonia Águila, Rosina Noto, Ginés Luengo-Gil, Salvador Espín, Nataliya Bohdan, María Eugenia de la Morena-Barrio, Julia Peñas, Maria Carmen Rodenas, Vicente Vicente, Javier Corral, Mauro Manno, Irene Martínez-Martínez
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 516 (2021)
N-linked glycosylation is a crucial post-translational modification involved in protein folding, function, and clearance. N-linked glycosylation is also used therapeutically to enhance the half-lives of many proteins. Antithrombin, a serpin with four
Externí odkaz:
https://doaj.org/article/3a3dfee44a884c1f95f4937b15c557b7
Autor:
Irene Martínez-Martínez, José Ramón González-Porras, María José Cebeira, Felipe de Arriba, Salvador Espín, Nataliya Bohdan, Fernando José Corrales, Javier Corral, Vicente Vicente
Publikováno v:
Haematologica, Vol 101, Iss 10 (2016)
Externí odkaz:
https://doaj.org/article/687a1343c9b7499995021a099309210f
Autor:
Nataliya Bohdan, Salvador Espín, Sonia Águila, Raúl Teruel-Montoya, Vicente Vicente, Javier Corral, Irene Martínez-Martínez
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157834 (2016)
Heparanase is an endoglycosidase that participates in morphogenesis, tissue repair, heparan sulphates turnover and immune response processes. It is over-expressed in tumor cells favoring the metastasis as it penetrates the endothelial layer that line
Externí odkaz:
https://doaj.org/article/ddd25526f4214edaa561a03124a4c68d
Autor:
Luisa Fernanda Castillo-Dávila, Carlos Jesús Torres-Anaya, Raquel Vazquez-Apodaca, Hector Borboa-Olivares, Salvador Espino-y-Sosa, Johnatan Torres-Torres
Publikováno v:
BMC Anesthesiology, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Laparoscopic cholecystectomy is known for its minimally invasive nature, but postoperative pain management remains challenging. Despite the enhanced recovery after surgery (ERAS) protocol, regional analgesic techniques like modifi
Externí odkaz:
https://doaj.org/article/ca6869fcd18b4f7e9cd2f81be731bb5e
Autor:
María del Carmen Cardós-Alonso, Lucía Otero-Varela, María Redondo, Miriam Uzuriaga, Myriam González, Tatiana Vazquez, Alberto Blanco, Salvador Espinosa, Ana María Cintora-Sanz
Publikováno v:
International Journal of Emergency Medicine, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Introduction Mass casualty incidents (MCI) are unforeseeable and complex events that occur worldwide, therefore enhancing the training that medical first responders (MFRs) receive is fundamental to strengthening disaster preparedness and res
Externí odkaz:
https://doaj.org/article/e65c984b3ed24d1f912385172391824f
Autor:
Maria Carmen Rodenas, Julia Peñas-Martínez, Irene Pardo-Sánchez, David Zaragoza-Huesca, Carmen Ortega-Sabater, Jorge Peña-García, Salvador Espín, Guillermo Ricote, Sofía Montenegro, Francisco Ayala de la Peña, Ginés Luengo-Gil, Andrés Nieto, Francisco García-Molina, Vicente Vicente, Francesco Bernardi, Maria Luisa Lozano, Victoriano Mulero, Horacio Pérez-Sánchez, Alberto Carmona-Bayonas, Irene Martínez-Martínez
Hepsin is a type II transmembrane serine protease whose expression has been linked to greater tumorigenicity and worse prognosis in different tumors such as prostate and gastric cancer. Recently, our group described hepsin expression in the primary b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62b6a51224dde2e2af634e9e94097278
https://doi.org/10.1101/2022.10.01.510038
https://doi.org/10.1101/2022.10.01.510038