Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Salundi Basappa"'
Autor:
Jong Hyun Lee, Chakrabhavi Dhananjaya Mohan, Amudha Deivasigamani, Young Yun Jung, Shobith Rangappa, Salundi Basappa, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, Manoj Garg, Zhi-Xiu Lin, Kanchugarakoppal S. Rangappa, Gautam Sethi, Kam Man Hui, Kwang Seok Ahn
Publikováno v:
Journal of Advanced Research, Vol 26, Iss , Pp 83-94 (2020)
Introduction: Epithelial-mesenchymal transition (EMT) is a process of transdifferentiation where epithelial cells attain mesenchymal phenotype to gain invasive properties and thus, can contribute to metastasis of tumor cells. Objectives: The antimeta
Externí odkaz:
https://doaj.org/article/b49452f32a3546068e13458d992b5aa4
Autor:
Salundi Basappa, Gautam Sethi, Chakrabhavi Dhananjaya Mohan, Vijai Kumar Gupta, Habbanakuppe D. Preetham, Shobith Rangappa, S. Chandra Nayaka, Kanchugarakoppal S. Rangappa
Publikováno v:
Seminars in Cancer Biology. 80:157-182
Signal transducer and activator of transcription (STAT) proteins are latent transcription factors that reside in the cytoplasm of several types of cells. In canonical signaling, upon stimulation by cytokines and growth factors, STATs get activated an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ea668dedbcc51908be4be3dd372a48
https://doi.org/10.1016/j.semcancer.2020.03.016
https://doi.org/10.1016/j.semcancer.2020.03.016
Autor:
Salundi Basappa, Vanessa Tan, Gilles J. Guillemin, Sharron Chow, Benjamin Heng, Abid Bhat, Musthafa Mohamed Essa, Saravana Babu Chidambaram
Publikováno v:
Neurotoxicity Research. 39:1238-1250
Phosphodiesterase-10A (PDE10A) hydrolyse the secondary messengers cGMP and cAMP, two molecules playing important roles in neurodevelopment and brain functions. PDE10A is associated to progression of neurodegenerative diseases like Alzheimer's, Parkin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::762bb2bb761bd2b0758cce696d6149a7
https://doi.org/10.1007/s12640-021-00368-4
https://doi.org/10.1007/s12640-021-00368-4
Autor:
Arunachalam Chinnathambi, Young Yun Jung, Amudha Deivasigamani, Kanchugarakoppal S. Rangappa, Salundi Basappa, Kam M. Hui, Shobith Rangappa, Manoj Garg, Zhi-Xiu Lin, Sulaiman Ali Alharbi, Chakrabhavi Dhananjaya Mohan, Kwang Seok Ahn, Gautam Sethi, Jong Hyun Lee, Tahani Awad Alahmadi
Publikováno v:
Journal of Advanced Research
Journal of Advanced Research, Vol 26, Iss, Pp 83-94 (2020)
Journal of Advanced Research, Vol 26, Iss, Pp 83-94 (2020)
Graphical abstract
Highlights • Brusatol affects migration and invasion ability of HCC cells. • Brusatol affects EMT process through modulation of STAT3 activation pathway. • Brusatol mitigates tumorigenesis and metastasis in HCC preclinic
Highlights • Brusatol affects migration and invasion ability of HCC cells. • Brusatol affects EMT process through modulation of STAT3 activation pathway. • Brusatol mitigates tumorigenesis and metastasis in HCC preclinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61abe6ded133ba56728c0771e649e16c
https://doi.org/10.1016/j.jare.2020.07.004
https://doi.org/10.1016/j.jare.2020.07.004
Autor:
Kwang Seok Ahn, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Salundi Basappa, Gautam Sethi, Kanchugarakoppal S. Rangappa, Chakrabhavi Dhananjaya Mohan, Kodappully Sivaraman Siveen, Jong Hyun Lee, Shobith Rangappa, Muthu K. Shanmugam, Sulaiman Ali Alharbi
Publikováno v:
Biochimie. 175:58-68
Hepatocellular carcinoma (HCC) is a major malignancy that stands second in terms of global cancer-related mortality. STAT3 has been described as a latent transcription factor that promotes tumorigenesis. This study was designed to examine the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6606e4df1460a2a8c6551aa8cdd748e5
https://doi.org/10.1016/j.biochi.2020.05.006
https://doi.org/10.1016/j.biochi.2020.05.006
Autor:
Swetha Hari, Umashakara Muddegowda, Kanchugarakoppal S. Rangappa, Chakrabhavi Dhananjaya Mohan, Habbanakuppe D. Preetham, Salundi Basappa, Israel Vlodavsky, Toreshettahally R. Swaroop, Gautam Sethi
Publikováno v:
Current Organic Synthesis. 17:243-250
Design of chemically novel, biologically potent small heterocyclic molecules with anticancer activities, which targets the enzyme heparanase has gained prominent clinical interest. We have synthesized a novel class of carboxamide derivatives by coupl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5aa53b8ddd7cd820a83cb68ed70bfde
https://doi.org/10.2174/1570179417666200225123329
https://doi.org/10.2174/1570179417666200225123329
Autor:
Chakrabhavi Dhananjaya Mohan, Sulaiman Ali Alharbi, Alan Prem Kumar, Kanchugarakoppal S. Rangappa, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Salundi Basappa, Jong Hyun Lee, Kwang Seok Ahn, Gautam Sethi, Shobith Rangappa
Publikováno v:
Biomolecules
Volume 9
Issue 12
Volume 9
Issue 12
STAT3 is an oncogenic transcription factor that regulates the expression of genes which are involved in malignant transformation. Aberrant activation of STAT3 has been observed in a wide range of human malignancies and its role in negative prognosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbfa3651f8b12b137dc2af20e6f881c3
https://pubmed.ncbi.nlm.nih.gov/31847229
https://pubmed.ncbi.nlm.nih.gov/31847229
Autor:
Kanchugarakoppal S. Rangappa, Nurfarhanah Bte Syed Sulaiman, Shobith Rangappa, Vijay Pandey, Peter E. Lobie, Alan Prem Kumar, Chakrabhavi Dhananjaya Mohan, Hanumantharayappa Bharathkumar, Salundi Basappa
Publikováno v:
International Journal of Oncology. 49:1221-1229
Persistent activation of signal transducer and activator of transcription 3 (STAT3) is associated with the progression of a range of tumors. In this report, we present the anticancer activity of 2-(1-(4-(2-cyanophenyl)1-benzyl‑1H-indol-3-yl)-5-(4-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d4602f65139c53176c47dbe4ee4ab2
https://doi.org/10.3892/ijo.2016.3615
https://doi.org/10.3892/ijo.2016.3615
Autor:
Qing-Yun Chong, Salundi Basappa, Mengyi Zhang, Lan Ma, Yi-Jun Chen, Mingliang You, Tao Zhu, Han-Ming Poh, Peter E. Lobie, Arindam Banerjee, Liang Liu, Vijay Pandey
Publikováno v:
Oncotarget
// Qing-Yun Chong 1 , Ming-Liang You 1, 2 , Vijay Pandey 1 , Arindam Banerjee 1 , Yi-Jun Chen 1, 2 , Han-Ming Poh 1, 2 , Mengyi Zhang 1, 2 , Lan Ma 3 , Tao Zhu 4, 5 , Salundi Basappa 6 , Liang Liu 7, 8 and Peter E. Lobie 1, 2, 3, 9 1 Cancer Science I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b5042289314078a07907dac3540d67
https://pubmed.ncbi.nlm.nih.gov/29088778
https://pubmed.ncbi.nlm.nih.gov/29088778
Autor:
Salundi Basappa, Vijay Pandey, M. Choolani, Peter E. Lobie, Qing-Yun Chong, R.Y.J. Huang, Yanxin Wang
Publikováno v:
ESMO Open. 3:A211
Introduction Human BAD (hBAD) is a pro-apoptotic Bcl-2 family member, whose apoptotic functions can be inactivated through phosphorylation of specific residues including Ser99. Clinically, BAD phosphorylation has been reported to indicate poor surviv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b41edb3b19bd73207ad1a2cb97a47e6
https://doi.org/10.1136/esmoopen-2018-eacr25.500
https://doi.org/10.1136/esmoopen-2018-eacr25.500