A novel role for osteopontin in macrophage-mediated amyloid-beta clearance in Alzheimer's models

Autor: Rentsendorj, A, Sheyn, J, Fuchs, D-T, Daley, D, Salumbides, BC, Schubloom, HE, Hart, NJ, Li, S, Hayden, EY, Teplow, DB, Black, KL, Koronyo, Y, Koronyo-Hamaoui, M

Publikováno v: Rentsendorj, A; Sheyn, J; Fuchs, D-T; Daley, D; Salumbides, BC; Schubloom, HE; et al.(2018). A novel role for osteopontin in macrophage-mediated amyloid-beta clearance in Alzheimer's models. BRAIN BEHAVIOR AND IMMUNITY, 67, 163-180. doi: 10.1016/j.bbi.2017.08.019. UCLA: Retrieved from: http://www.escholarship.org/uc/item/7x21944x

Osteopontin (OPN), a matricellular immunomodulatory cytokine highly expressed by myelomonocytic cells, is known to regulate immune cell migration, communication, and response to brain injury. Enhanced cerebral recruitment of monocytes achieved throug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::7a60a25b9b6bdf43d6fd2eae7e8e7c86
http://www.escholarship.org/uc/item/7x21944x

BATF3 Protects Against Metabolic Syndrome and Maintains Intestinal Epithelial Homeostasis.

Autor: Hamade H; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Stamps JT; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Stamps DT; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., More SK; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Thomas LS; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Blackwood AY; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Lahcene NL; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Castanon SL; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Salumbides BC; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Shimodaira Y; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Goodridge HS; Research Division of Immunology, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Targan SR; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Michelsen KS; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Research Division of Immunology, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Jun 22; Vol. 13, pp. 841065. Date of Electronic Publication: 2022 Jun 22 (Print Publication: 2022).

A novel role for osteopontin in macrophage-mediated amyloid-β clearance in Alzheimer's models.

Autor: Rentsendorj A; Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA., Sheyn J; Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA., Fuchs DT; Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA., Daley D; Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA., Salumbides BC; Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA., Schubloom HE; Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA., Hart NJ; Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA., Li S; Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA; Institute of Life Sciences, Wenzhou University, 276 Xueyuan Middle Rd, Lucheng Qu, Wenzhou Shi, Zhejiang Sheng 325027, China., Hayden EY; Department of Neurology, David Geffen School of Medicine at UCLA, Mary S. Easton Center for Alzheimer's Disease Research at UCLA, Brain Research Institute, Molecular Biology Institute, University of California, 635 Charles E. Young Dr. S., Los Angeles, CA 90095, USA., Teplow DB; Department of Neurology, David Geffen School of Medicine at UCLA, Mary S. Easton Center for Alzheimer's Disease Research at UCLA, Brain Research Institute, Molecular Biology Institute, University of California, 635 Charles E. Young Dr. S., Los Angeles, CA 90095, USA., Black KL; Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA., Koronyo Y; Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA., Koronyo-Hamaoui M; Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA; Department of Biomedical Sciences, Division of Applied Cell Biology and Physiology, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA 90048, USA. Electronic address: maya.koronyo@csmc.edu.

Publikováno v: Brain, behavior, and immunity [Brain Behav Immun] 2018 Jan; Vol. 67, pp. 163-180. Date of Electronic Publication: 2017 Aug 30.

Therapeutic effects of glatiramer acetate and grafted CD115⁺ monocytes in a mouse model of Alzheimer's disease.

Autor: Koronyo Y; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Salumbides BC; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA 2 F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Sheyn J; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Pelissier L; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Li S; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Ljubimov V; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Moyseyev M; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Daley D; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Fuchs DT; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Pham M; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Black KL; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Rentsendorj A; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA., Koronyo-Hamaoui M; 1 Department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA 3 Department of Biomedical Sciences, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA koronyom@cshs.org.

Publikováno v: Brain : a journal of neurology [Brain] 2015 Aug; Vol. 138 (Pt 8), pp. 2399-422. Date of Electronic Publication: 2015 Jun 06.

Alzheimer's disease in the retina: imaging retinal aβ plaques for early diagnosis and therapy assessment.

Autor: Koronyo Y; Department of Neurosurgery, Maxine Dunitz Neurosurgical Research Institute, Los Angeles, Calif, USA., Salumbides BC, Black KL, Koronyo-Hamaoui M

Publikováno v: Neuro-degenerative diseases [Neurodegener Dis] 2012; Vol. 10 (1-4), pp. 285-93. Date of Electronic Publication: 2012 Feb 10.