Irgafos 168 and Irganox 1076 as new cocaine cutting agents: A COVID-19 pandemic impact on cocaine profiling and trafficking in Brazil.

Autor: Ferrari Júnior E; Forensic Physics and Chemistry Laboratory, Criminalistics Institute - Civil Police of the Brazilian Federal District (PCDF), Brasilia, DF, Brazil., da Rocha TMV; Brainfarma Pharmaceutical Company, Anápolis, Goiás State 75132-020, Brazil., Santos JP; Laboratory of Photochemistry and Nanobiotechnology, Faculty of Ceilandia, University of Brasilia (UnB), Brasilia, DF, Brazil; Laboratory of Toxicological Analysis (AToxLab), Faculty of Ceilandia, University of Brasília (UnB), Brasilia, DF, Brazil., de Souza DM; Forensic Physics and Chemistry Laboratory, Criminalistics Institute - Civil Police of the Brazilian Federal District (PCDF), Brasilia, DF, Brazil., Gomes EB; Forensic Physics and Chemistry Laboratory, Criminalistics Institute - Civil Police of the Brazilian Federal District (PCDF), Brasilia, DF, Brazil., Alves BEP; Forensic Physics and Chemistry Laboratory, Criminalistics Institute - Civil Police of the Brazilian Federal District (PCDF), Brasilia, DF, Brazil., de Andrade Gomes J; Forensic Physics and Chemistry Laboratory, Criminalistics Institute - Civil Police of the Brazilian Federal District (PCDF), Brasilia, DF, Brazil., Salum LB; Forensic Physics and Chemistry Laboratory, Criminalistics Institute - Civil Police of the Brazilian Federal District (PCDF), Brasilia, DF, Brazil., Lunardi CN; Laboratory of Photochemistry and Nanobiotechnology, Faculty of Ceilandia, University of Brasilia (UnB), Brasilia, DF, Brazil., Arantes LC; Forensic Physics and Chemistry Laboratory, Criminalistics Institute - Civil Police of the Brazilian Federal District (PCDF), Brasilia, DF, Brazil., da Silva Santos V; Laboratory of Toxicological Analysis (AToxLab), Faculty of Ceilandia, University of Brasília (UnB), Brasilia, DF, Brazil. Electronic address: vsantosfarma@gmail.com.

Publikováno v: Forensic science international [Forensic Sci Int] 2024 Jan; Vol. 354, pp. 111911. Date of Electronic Publication: 2023 Dec 12.

N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia.

Autor: Salum LB; Laboratório de Química Medicinal e Computacional, Universidade de São Paulo, São Carlos, SP 13560-590, Brazil., Mascarello A; Laboratório Estrutura e Atividade, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil., Canevarolo RR; Centro Infantil Boldrini, Campinas, SP 13083-210, Brazil., Altei WF; Laboratório de Química Medicinal e Computacional, Universidade de São Paulo, São Carlos, SP 13560-590, Brazil., Laranjeira AB; Centro Infantil Boldrini, Campinas, SP 13083-210, Brazil., Neuenfeldt PD; Laboratório Estrutura e Atividade, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil., Stumpf TR; Laboratório Estrutura e Atividade, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil., Chiaradia-Delatorre LD; Laboratório Estrutura e Atividade, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil., Vollmer LL; Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA 15260, USA., Daghestani HN; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA 15260, USA., de Souza Melo CP; Centro Infantil Boldrini, Campinas, SP 13083-210, Brazil., Silveira AB; Centro Infantil Boldrini, Campinas, SP 13083-210, Brazil., Leal PC; Laboratório Estrutura e Atividade, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil., Frederico MJ; Laboratório de Neurobiologia da Dor e Inflamação, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil., do Nascimento LF; Laboratório de Neurobiologia da Dor e Inflamação, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil., Santos AR; Laboratório de Neurobiologia da Dor e Inflamação, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil., Andricopulo AD; Laboratório de Química Medicinal e Computacional, Universidade de São Paulo, São Carlos, SP 13560-590, Brazil., Day BW; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Yunes RA; Laboratório Estrutura e Atividade, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil., Vogt A; Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA 15260, USA; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15260, USA., Yunes JA; Centro Infantil Boldrini, Campinas, SP 13083-210, Brazil. Electronic address: andres@boldrini.org.br., Nunes RJ; Laboratório Estrutura e Atividade, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil. Electronic address: nunesricardoj@gmail.com.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2015; Vol. 96, pp. 504-18. Date of Electronic Publication: 2015 Feb 23.

Gallium(III) complexes with 2-acetylpyridine-derived thiosemicarbazones: antimicrobial and cytotoxic effects and investigation on the interactions with tubulin.

Autor: Lessa JA; Instituto de Química, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, 20550-013, Brazil., Soares MA, dos Santos RG, Mendes IC, Salum LB, Daghestani HN, Andricopulo AD, Day BW, Vogt A, Beraldo H

Publikováno v: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine [Biometals] 2013 Feb; Vol. 26 (1), pp. 151-65. Date of Electronic Publication: 2013 Jan 24.

A fragment-based approach for ligand binding affinity and selectivity for the liver X receptor beta.

Autor: Salum LB; Laboratório de Química Medicinal e Computacional, Centro de Biotecnologia Molecular Estrutural, Instituto de Física de São Carlos, Universidade de São Paulo, Av. Trabalhador São-Carlense 400, 13560-970 São Carlos, SP, Brazil., Andricopulo AD, Honório KM

Publikováno v: Journal of molecular graphics & modelling [J Mol Graph Model] 2012 Feb; Vol. 32, pp. 19-31. Date of Electronic Publication: 2011 Oct 07.

Fragment-based QSAR strategies in drug design.

Autor: Salum LB; Laboratório de Química Medicinal e Computacional, Instituto de Física de São Carlos, Universidade de São Paulo, Av. Trabalhador São-carlense 400, 13560-970, São Carlos-SP, Brazil +55 16 3373 8095 ; +55 16 3373 9881 ; aandrico@ifsc.usp.br., Andricopulo AD

Publikováno v: Expert opinion on drug discovery [Expert Opin Drug Discov] 2010 May; Vol. 5 (5), pp. 405-12. Date of Electronic Publication: 2010 Mar 31.