Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis

Autor: Datta, Harish K, Kringen, Marianne K, Tuck, Stephen P, Salpingidou, Georgia, Olstad, Ole K, Gautvik, Kaare M, Cockell, Simon J, Gautvik, Vigdis T, Prediger, Michael, Wu, Jun Jie, Birch, Mark A, Reppe, Sjur

Publikováno v: International journal of molecular sciences, 2022, Vol.23(6), pp.2957 [Peer Reviewed Journal]
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 2957

Mechanical loading exerts a profound influence on bone density and architecture, but the exact mechanism is unknown. Our study shows that expression of the neurological transcriptional factor zinc finger of the cerebellum 1 (ZIC1) is markedly increas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9964391db26f33e0c6dee0673db9adac
http://dro.dur.ac.uk/36397/1/36397.pdf

A Novel Role for the Nuclear Membrane Protein Emerin in Association of the Centrosome to the Outer Nuclear Membrane

Autor: Salpingidou, Georgia, Smertenko, Andrei, Hausmanowa-Petrucewicz, Irena, Hussey, Patrick J., Hutchison, Chris J.

Publikováno v: The Journal of Cell Biology, 2007 Sep 01. 178(6), 897-904.

Externí odkaz: https://www.jstor.org/stable/30050022

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Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis.

Autor: Datta HK; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.; Blood Sciences, South Tees Hospitals NHS Foundation Trust, Middlesbrough TS4 3BW, UK., Kringen MK; Center for Psychopharmacology, Diakonhjemmet Hospital, 0319 Oslo, Norway., Tuck SP; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK., Salpingidou G; Department of Engineering, Faculty of Science, Durham University, Durham DH1 3 LE, UK., Olstad OK; Department of Medical Biochemistry, Oslo University Hospital, 0424 Oslo, Norway., Gautvik KM; Unger-Vetlesen Institute, Lovisenberg Diaconal Hospital, 0440 Oslo, Norway., Cockell SJ; School of Biomedical, Nutritional and Sport Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK., Gautvik VT; Unger-Vetlesen Institute, Lovisenberg Diaconal Hospital, 0440 Oslo, Norway., Prediger M; Blood Sciences, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Royal Victoria Infirmary, Newcastle upon Tyne NE2 4HH, UK., Wu JJ; Department of Engineering, Faculty of Science, Durham University, Durham DH1 3 LE, UK., Birch MA; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK., Reppe S; Department of Medical Biochemistry, Oslo University Hospital, 0424 Oslo, Norway.; Unger-Vetlesen Institute, Lovisenberg Diaconal Hospital, 0440 Oslo, Norway.; Department of Plastic and Reconstructive Surgery, Oslo University Hospital, 0424 Oslo, Norway.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 09; Vol. 23 (6). Date of Electronic Publication: 2022 Mar 09.