Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Salome Tabea Spieth"'
Autor:
Aynur Sönmez, Tanja Hering, Salome Tabea Spieth, Kerstin Kojer, Christian Litke, Birgit Liss, Jenniver Koch, Rosanna Parlato, Michael Orth, Rasem Mustafa
Publikováno v:
Pathogenic mechanisms.
Background Transcriptional and metabolic dysregulation are known to occur in Huntington’s disease (HD). Mutant huntingtin (mHTT) protein affects several cellular functions hindering the identification of the primary pathogenic event. Impaired trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5e1297b95b321ba01f009910ca0a4ac
https://doi.org/10.1136/jnnp-2018-ehdn.9
https://doi.org/10.1136/jnnp-2018-ehdn.9
Autor:
Aynur Soenmez, Holger Bierhoff, Rasem Mustafa, Jose E. Naranjo, Rosanna Parlato, Salome Tabea Spieth, Grzegorz Kreiner, Francesca Tuorto, Birgit Liss, Christian Litke
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 87:A16.1-A16
Background The expansion of CAG repeats in the mutant huntingtin (mHtt) protein impairs, among other fundamental cellular functions, the transcription of rRNA genes causing inhibition of rRNA synthesis and consequent disruption of nucleolar integrity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::481865e8f86441234eab5e82c97b5c91
https://doi.org/10.1136/jnnp-2016-314597.51
https://doi.org/10.1136/jnnp-2016-314597.51