Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Salome, Murinello"'
Autor:
Stephen A. Beers, Mark S. Cragg, Martin J. Glennie, Jessica L. Teeling, Diego Gomez-Nicola, Patrick J. Duriez, Andrew J. Steele, Francesco Forconi, Ian Tracy, Salome Murinello, Kerry L. Cox, Alexander Earley, Rena Liu, Khiyam Hussain, Lang Dou, Lekh N. Dahal
This file contains supplementary data showing phenotypic/cytokine/chemokine changes in immune cell population following stimulation/tumour inoculation. The data also demonstrate that monocyte and neutrophil are not required for mAb mediated deletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b512d898dbe1ff26b9592470f3760de
https://doi.org/10.1158/0008-5472.22414716
https://doi.org/10.1158/0008-5472.22414716
Autor:
Stephen A. Beers, Mark S. Cragg, Martin J. Glennie, Jessica L. Teeling, Diego Gomez-Nicola, Patrick J. Duriez, Andrew J. Steele, Francesco Forconi, Ian Tracy, Salome Murinello, Kerry L. Cox, Alexander Earley, Rena Liu, Khiyam Hussain, Lang Dou, Lekh N. Dahal
Tumors routinely attract and co-opt macrophages to promote their growth, angiogenesis, and metastasis. Macrophages are also the key effector cell for mAb therapies. Here we report that the tumor microenvironment creates an immunosuppressive signature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb3b7826c615c5fc5826089fe7d7823c
https://doi.org/10.1158/0008-5472.c.6509061.v1
https://doi.org/10.1158/0008-5472.c.6509061.v1
Autor:
Marin L. Gantner, Salome Murinello, Edith Aguilar, Peter E. Wright, Martin Friedlander, Mitchell Prins, Rebecca B. Berlow, Ayumi Usui-Ouchi
Publikováno v:
Proc Natl Acad Sci U S A
Retinal neovascularization (NV), a leading cause of vision loss, results from localized hypoxia that stabilizes the hypoxia-inducible transcription factors HIF-1α and HIF-2α, enabling the expression of angiogenic factors and genes required to maint
Autor:
Michael I. Dorrell, Carli M Wittgrove, Yoshihiko Usui, Maki Kitano, Edith Aguilar, Martin Friedlander, Amelia Schricker, Susumu Sakimoto, Peter D. Westenskow, Salome Murinello, H. Maura Friedlander, Yoshihiro Wakabayashi
Publikováno v:
Glia. 67:332-344
Ischemia-induced angiogenesis contributes to various neuronal and retinal diseases, and often results in neurodegeneration and visual impairment. Current treatments involve the use of anti-VEGF agents but are not successful in all cases. In this stud
Autor:
Salome, Murinello, Yoshihiko, Usui, Susumu, Sakimoto, Maki, Kitano, Edith, Aguilar, H Maura, Friedlander, Amelia, Schricker, Carli, Wittgrove, Yoshihiro, Wakabayashi, Michael I, Dorrell, Peter D, Westenskow, Martin, Friedlander
Publikováno v:
Glia. 67(2)
Ischemia-induced angiogenesis contributes to various neuronal and retinal diseases, and often results in neurodegeneration and visual impairment. Current treatments involve the use of anti-VEGF agents but are not successful in all cases. In this stud
Autor:
Mari Gantner, Joan W. Miller, Salome Murinello, Martin Friedlander, Deeba Husain, Jessica Lasky-Su, Inês Laíns
Publikováno v:
Progress in retinal and eye research. 69
Metabolomics is the qualitative and quantitative assessment of the metabolites (small molecules 1.5 kDa) in body fluids. The metabolites are the downstream of the genetic transcription and translation processes and also downstream of the interactions
Autor:
Felicitas Bucher, Michael I. Dorrell, Lea Scheppke, Edith Aguilar, Peter D. Westenskow, Martin Friedlander, Liliana P Paris, Salome Murinello, Susumu Sakimoto, Yoshihiko Usui
Publikováno v:
Annual review of vision science. 1
The retina consists of organized layers of photoreceptors, interneurons, glia, epithelial cells, and endothelial cells. The economic model of supply and demand used to appropriately determine cost is highly applicable to the retina, in which the extr
Autor:
Ravenska Wagey, Edith Aguilar, Felicitas Bucher, Jennifer K Trombley, Peter D. Westenskow, Salome Murinello, Susumu Sakimoto, Yoshihiko Usui, Regis Fallon, Kelsey Lee, Carrie Peters, Martin Friedlander, Elizabeth L. Scheppke, Valentina Marchetti
Publikováno v:
JCI Insight. 2
Vascular abnormalities are a common component of eye diseases that often lead to vision loss. Vaso-obliteration is associated with inherited retinal degenerations, since photoreceptor atrophy lowers local metabolic demands and vascular support to tho
Autor:
Salome Murinello, Matthew S. Macauley, Peter D. Westenskow, Martin Friedlander, Stacey K. Moreno, Susumu Sakimoto
Publikováno v:
Journal of Visualized Experiments.
Microglia are the tissue resident macrophages of the central nervous system (CNS) and they perform a variety of functions that support CNS homeostasis, including phagocytosis of damaged synapses or cells, debris, and/or invading pathogens. Impaired p
Autor:
Patrick J. Duriez, Ian Tracy, Salome Murinello, Rena Liu, Andrew J. Steele, Mark S. Cragg, Alexander Earley, Lang Dou, Lekh N. Dahal, Stephen A. Beers, Diego Gomez-Nicola, Jessica L. Teeling, Kerry L. Cox, Khiyam Hussain, Martin J. Glennie, Francesco Forconi
Publikováno v:
Cancer research. 77(13)
Tumors routinely attract and co-opt macrophages to promote their growth, angiogenesis, and metastasis. Macrophages are also the key effector cell for mAb therapies. Here we report that the tumor microenvironment creates an immunosuppressive signature