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Stereoselective synthesis of 3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one derivatives as PIM kinase inhibitors inspired from marine alkaloids.

Autor: Casuscelli F; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy.; Accelera, Nerviano Medical Sciences, Nerviano, Milan, Italy., Ardini E; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Avanzi N; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Badari A; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Casale E; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Disingrini T; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Donati D; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Ermoli A; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Felder ER; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Galvani A; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Isacchi A; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Menichincheri M; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Montemartini M; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Orrenius C; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Piutti C; Accelera, Nerviano Medical Sciences, Nerviano, Milan, Italy., Salom B; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy., Papeo G; Oncology, Nerviano Medical Sciences, Nerviano (Mi), Italy.

Publikováno v: Chirality [Chirality] 2022 Nov; Vol. 34 (11), pp. 1437-1452. Date of Electronic Publication: 2022 Aug 12.

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Akademický článek

48 (PB038) - NMS-173, a potent, covalent second generation IDH1/IDH2 inhibitor

Publikováno v: In European Journal of Cancer October 2022 174 Supplement 1:S17-S17

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Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury.

Autor: Magnaghi P; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy. paola.magnaghi@nervianoms.com., Salom B; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy., Cozzi L; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy., Amboldi N; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy., Ballinari D; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy., Tamborini E; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Gasparri F; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy., Montagnoli A; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy., Raddrizzani L; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy., Somaschini A; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy., Bosotti R; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy., Orrenius C; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy., Bozzi F; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Pilotti S; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Galvani A; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy., Sommer J; Chordoma Foundation, Durham, North Carolina., Stacchiotti S; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Isacchi A; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2018 Mar; Vol. 17 (3), pp. 603-613. Date of Electronic Publication: 2017 Dec 13.

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Establishment and genomic characterization of the new chordoma cell line Chor-IN-1.

Autor: Bosotti R; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy. roberta.bosotti@nervianoms.com., Magnaghi P; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Di Bella S; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Cozzi L; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Cusi C; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Bozzi F; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Beltrami N; L.C. Laboratori Campisi, Avola (SR), Italy., Carapezza G; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Ballinari D; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Amboldi N; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Lupi R; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Somaschini A; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Raddrizzani L; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Salom B; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Galvani A; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy., Stacchiotti S; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Tamborini E; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Isacchi A; Oncology, Nerviano Medical Sciences, Nerviano, (MI), Italy.

Publikováno v: Scientific reports [Sci Rep] 2017 Aug 23; Vol. 7 (1), pp. 9226. Date of Electronic Publication: 2017 Aug 23.

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Bibliometric Insights in Advances of Chordoma: Global Trends and Research Development in the Last Decade.

Autor: Xiao, Yu¹ (AUTHOR), Yu, Wenlong¹ (AUTHOR), Zheng, Jianhu² (AUTHOR), Cheng, Lin¹ (AUTHOR), Ding, Xing¹ (AUTHOR), Qiao, Liang³ (AUTHOR), Wu, Xuequn¹ (AUTHOR) junming236@aliyun.com, Ma, Junming¹ (AUTHOR) wxqlzjj@163.com

Publikováno v: Orthopaedic Surgery. Oct2023, Vol. 15 Issue 10, p2505-2514. 10p.

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