A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice.

Autor: Leu CL; Institute of Neurogenomics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany., Lam DD; Institute of Neurogenomics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany., Salminen AV; Institute of Neurogenomics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany., Wefers B; Institute of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany., Becker L; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Center Munich, Neuherberg, Germany., Garrett L; Institute of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Center Munich, Neuherberg, Germany., Rozman J; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Center Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg., Wurst W; Institute of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Neurodegenerative Diseases (DZNE), Site Munich, Germany.; Chair of Developmental Genetics, TUM School of Life Sciences, Technische Universität München, Freising, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Hrabě de Angelis M; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Center Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Chair of Experimental Genetics, TUM School of Life Sciences, Technische Universität, München, Freising, Germany., Hölter SM; Institute of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany., Winkelmann J; Institute of Neurogenomics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Williams RH; Institute of Neurogenomics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.

Publikováno v: Sleep [Sleep] 2024 May 10; Vol. 47 (5).

Consensus guidelines on the construct validity of rodent models of restless legs syndrome.

Autor: Salminen AV; Institute of Neurogenomics, Helmholtz Zentrum München GmbH - German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Human Genetics, Klinikum rechts der Isar, Technische Universität München, 81675 Munich, Germany., Clemens S; Department of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA., García-Borreguero D; Sleep Research Institute, 28036 Madrid, Spain., Ghorayeb I; Département de Neurophysiologie Clinique, Pôle Neurosciences Cliniques, CHU de Bordeaux, 33076 Bordeaux, France.; Université de Bordeaux, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, UMR 5287, 33076 Bordeaux, France.; CNRS, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, UMR 5287, 33076 Bordeaux, France., Li Y; Department of Neurology, Norman Fixel Institute for Neurological Diseases, College of Medicine, University of Florida, Gainesville, FL 32610, USA., Manconi M; Sleep Medicine Unit, Regional Hospital of Lugano, Neurocenter of Southern Switzerland, 6900 Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, 6900 Lugano, Switzerland.; Department of Neurology, University Hospital Inselspital, 3010 Bern, Switzerland., Ondo W; Houston Methodist Hospital Neurological Institute, Weill Cornell Medical School, Houston, TX 77070, USA., Rye D; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA., Siegel JM; Neuropsychiatric Institute and Brain Research Institute, University of California, Los Angeles, CA 90095, USA.; Neurobiology Research, Veterans Administration Greater Los Angeles Healthcare System, North Hills, CA 91343, USA., Silvani A; Department of Biomedical and Neuromotor Sciences Alma Mater Studiorum, Università di Bologna, 48121 Ravenna Campus, Ravenna, Italy., Winkelman JW; Departments of Psychiatry and Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Allen RP; Department of Neurology, Johns Hopkins University, Baltimore, MD 21224, USA., Ferré S; Integrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA.

Publikováno v: Disease models & mechanisms [Dis Model Mech] 2022 Aug 01; Vol. 15 (8). Date of Electronic Publication: 2022 Aug 10.

Consensus Guidelines on Rodent Models of Restless Legs Syndrome.

Autor: Salminen AV; Institute of Neurogenomics, Helmholtz Zentrum München GmbH - German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Silvani A; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy., Allen RP; Department of Neurology, Johns Hopkins University, Baltimore, Maryland, USA., Clemens S; Department of Physiology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA., Garcia-Borreguero D; Sleep Research Institute, Madrid, Spain., Ghorayeb I; Département de Neurophysiologie Clinique, Pôle Neurosciences Cliniques, CHU de Bordeaux, Bordeaux, France.; Université de Bordeaux, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, UMR 5287, Bordeaux, France.; CNRS, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, UMR 5287, Bordeaux, France., Ferré S; National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, Maryland, USA., Li Y; Norman Fixel Institute for Neurological Diseases, Department of Neurology, College of Medicine, University of Florida, Gainesville, Florida, USA., Ondo W; Houston Methodist Hospital Neurological Institute, Weill Cornell Medical School, Houston, Texas, USA., Picchietti DL; University of Illinois School of Medicine, Carle Illinois College of Medicine and Carle Foundation Hospital, Urbana, Illinois, USA., Rye D; Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA., Siegel JM; Neuropsychiatric Institute and Brain Research Institute, University of California, Los Angeles, Los Angeles, California, USA.; Neurobiology Research, Veterans Administration Greater Los Angeles Healthcare System, North Hills, California, USA., Winkelman JW; Departments of Psychiatry and Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Manconi M; Sleep Medicine Unit, Regional Hospital of Lugano, Neurocenter of Southern Switzerland, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.; Department of Neurology, University Hospital Inselspital, Bern, Switzerland.

Publikováno v: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2021 Mar; Vol. 36 (3), pp. 558-569. Date of Electronic Publication: 2020 Dec 31.

Identification of Restless Legs Syndrome Genes by Mutational Load Analysis.

Autor: Tilch E; Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Institute of Neurogenomics, Neuherberg, Germany., Schormair B; Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Institute of Neurogenomics, Neuherberg, Germany., Zhao C; Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Institute of Neurogenomics, Neuherberg, Germany., Salminen AV; Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Institute of Neurogenomics, Neuherberg, Germany., Antic Nikolic A; Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Institute of Neurogenomics, Neuherberg, Germany., Holzknecht E; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Högl B; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Poewe W; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Bachmann CG; Department of Neurology, Paracelsus Clinic, Osnabrück, Germany., Paulus W; Department of Clinical Neurophysiology, University Medical Center, Georg August University Göttingen, Göttingen, Germany., Trenkwalder C; Clinic for Neurosurgery, University Medical Center, Georg August University Göttingen, Göttingen, Germany.; Center of Parkinsonism and Movement Disorders, Paracelsus-Elena Hospital, Kassel, Germany., Oertel WH; Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Institute of Neurogenomics, Neuherberg, Germany., Hornyak M; Neuropsychiatry Center Erding/Munich, Erding, Germany., Fietze I; Department of Cardiology and Angiology, Center of Sleep Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany., Berger K; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Lichtner P; Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Institute of Human Genetics, Neuherberg, Germany., Gieger C; Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Institute of Epidemiology II, Neuherberg, Germany., Peters A; Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Institute of Epidemiology II, Neuherberg, Germany., Müller-Myhsok B; Munich Cluster for Systems Neurology, Munich, Germany.; Max Planck Institute of Psychiatry, Munich, Germany.; Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom., Hoischen A; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands., Winkelmann J; Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Institute of Neurogenomics, Neuherberg, Germany.; Munich Cluster for Systems Neurology, Munich, Germany.; Department of Neurogenetics and Institute of Human Genetics, Technical University of Munich, Munich, Germany., Oexle K; Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Institute of Neurogenomics, Neuherberg, Germany.

Publikováno v: Annals of neurology [Ann Neurol] 2020 Feb; Vol. 87 (2), pp. 184-193. Date of Electronic Publication: 2019 Dec 19.

Reply to: A note on rotigotine for restless legs syndrome after renal transplantation.

Autor: Salminen AV; Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany., Allen RP; Sleep Disorders Center, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, United States.; Department of Neurology, Johns Hopkins University, Baltimore, Maryland, United States., Högl B; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Inoue Y; Japan Somnology Center, Neuropsychiatric Research Institute, Tokyo, Japan.; Department of Somnology, Tokyo Medical University, Tokyo, Japan., Oertel W; Department of Neurology, Philipps-Universität Marburg, Marburg, Germany., Winkelman JW; Harvard Medical School, Boston, Massachusetts, United States.; Departments of Psychiatry and Neurology, Massachusetts General Hospital, Boston, MA, United States., Trenkwalder C; Department Neurosurgery, University Medical Center, Goettingen, Germany.; Paracelsus-Elena Hospital, Kassel, Germany., Sampaio C; CHDI Foundation, Princeton, New Jersey, USA., Winkelmann J; Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany.; Chair Neurogenetics and Institute of Human Genetics, Technical University Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Publikováno v: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2019 Jan; Vol. 34 (1), pp. 152-153.