Zobrazeno 1 - 10
of 350
pro vyhledávání: '"Salman Siddiqui"'
Autor:
Paul E. Pfeffer, PhD, Thomas Brown, PhD, Rekha Chaudhuri, MD, Shoaib Faruqi, MD, Robin Gore, PhD, Liam G. Heaney, MD, Adel H. Mansur, PhD, Thomas Pantin, MD, Mitesh Patel, PhD, Hitasha Rupani, PhD, Salman Siddiqui, PhD, Aashish Vyas, MD, John Busby, PhD, Dr Martin Doherty, PhD, Dr Matthew Masoli, PhD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 3, Pp 100286- (2024)
Background: Severe asthma pathology encompasses a wide range of pulmonary and extrapulmonary treatable traits with a high prevalence of comorbidities. Although asthma-specific health-related quality-of-life measures are most sensitive to changes in a
Externí odkaz:
https://doaj.org/article/03d1f24037dc46fba4c829d8f676c433
Autor:
Salman Siddiqui, Thys van der Molen, Huib A M Kerstjens, Dave Singh, Chris Brightling, Maarten van den Berge, Alberto Papi, Klaus F Rabe, Leonardo M Fabbri, Monica Kraft, Martijn C Nawijn, Susan Muiser, Tessa M Kole
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Background Asthma is a heterogeneous disease with a prevalence and severity that differs between male and female patients.Question What are differences between male and female patients with asthma with regard to asthma control, lung function, inflamm
Externí odkaz:
https://doaj.org/article/9bc70945e83b454984afcfa5cfa39b16
Autor:
Zaid W. El-Husseini, Dmitry Khalenkow, Andy Lan, Thys van der Molen, Chris Brightling, Alberto Papi, Klaus F. Rabe, Salman Siddiqui, Dave Singh, Monica Kraft, Bianca Beghe, Maarten van den Berge, Djoke van Gosliga, Martijn C. Nawijn, Stefan Rose-John, Gerard H. Koppelman, Reinoud Gosens
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Asthma is stratified into type 2-high and type 2-low inflammatory phenotypes. Limited success has been achieved in developing drugs that target type 2-low inflammation. Previous studies have linked IL-6 signaling to severe asthma.
Externí odkaz:
https://doaj.org/article/e4d93162eadc447d86daca4b0d26e0df
Autor:
Tom Wilkinson, Anthony De Soyza, Miles Carroll, James D. Chalmers, Michael G. Crooks, Gareth Griffiths, Manu Shankar-Hari, Ling-Pei Ho, Alex Horsley, Chris Kell, Beatriz Lara, Biswa Mishra, Rachel Moate, Clive Page, Hitesh Pandya, Jason Raw, Fred Reid, Dinesh Saralaya, Ian C. Scott, Salman Siddiqui, Andy Ustianowski, Natalie van Zuydam, Ashley Woodcock, Dave Singh
Publikováno v:
ERJ Open Research, Vol 9, Iss 5 (2023)
Background Increased serum interleukin (IL)-33 predicts poor outcomes in patients hospitalised with coronavirus disease 2019 (COVID-19). We examined the efficacy and safety of tozorakimab, a monoclonal antibody that neutralises IL-33, in improving ou
Externí odkaz:
https://doaj.org/article/663594df92f142cd8da36d4a4738c12b
Autor:
Benjamin Gaston, Donna D. Gardner, Kenzie Mahan, Praveen Akuthota, Eneida A. Mendonca, Hannah Durrington, Nadzeya Marozkina, Rocio T. Martinez-Nunez, Dawn Newcomb, Benjamin Ainsworth, Arthur H. Owora, Kian Fan Chung, Samantha Walker, Stephen J. Fowler, Salman Siddiqui, Tonya Winders, Joe Zein, Nizar Jarjour, Yvonne J. Huang, Katherine N. Cahill, Ratko Djukanovic
Publikováno v:
ERJ Open Research, Vol 9, Iss 3 (2023)
Background Many patients have uncontrolled asthma despite available treatments. Most of the new asthma therapies have focused on type 2 (T2) inflammation, leaving an unmet need for innovative research into mechanisms of asthma beyond T2 and immunity.
Externí odkaz:
https://doaj.org/article/8f20c591769241669a5d4467cb34426b
Autor:
Courtney Coleman, Olivia Fulton, Jeanette Boyd, Clare Williams, Zena Powell, Christopher E. Brightling, Maarten van den Berge, Salman Siddiqui, Pippa Powell
Publikováno v:
Breathe, Vol 19, Iss 1 (2023)
Patient and public involvement in research is increasingly considered a cornerstone of good research practice, and the research community recognises people with lived experience as valuable stakeholders within the research process. European Respirato
Externí odkaz:
https://doaj.org/article/8854412ba3dd44fd948b49b3f041d560
Characteristics and risk factors for post-COVID-19 breathlessness after hospitalisation for COVID-19
Autor:
Luke Daines, Bang Zheng, Omer Elneima, Ewen Harrison, Nazir I. Lone, John R. Hurst, Jeremy S. Brown, Elizabeth Sapey, James D. Chalmers, Jennifer K. Quint, Paul Pfeffer, Salman Siddiqui, Samantha Walker, Krisnah Poinasamy, Hamish McAuley, Marco Sereno, Aarti Shikotra, Amisha Singapuri, Annemarie B. Docherty, Michael Marks, Mark Toshner, Luke S. Howard, Alex Horsley, Gisli Jenkins, Joanna C. Porter, Ling-Pei Ho, Betty Raman, Louise V. Wain, Christopher E. Brightling, Rachael A. Evans, Liam G. Heaney, Anthony De Soyza, Aziz Sheikh
Publikováno v:
ERJ Open Research, Vol 9, Iss 1 (2023)
Background Persistence of respiratory symptoms, particularly breathlessness, after acute coronavirus disease 2019 (COVID-19) infection has emerged as a significant clinical problem. We aimed to characterise and identify risk factors for patients with
Externí odkaz:
https://doaj.org/article/8110eed61f554330b29be4ff3cf019d1
Autor:
Ronald McDowell, Liam Heaney, Thomas Brown, Brendan Bunting, Hassan Burhan, Rekha Chaudhuri, Paddy Dennison, Shoaib Faruqi, Robin Gore, David J Jackson, Andrew Menzies-Gow, Thomas Pantin, Mitesh Patel, Paul Pfeffer, Salman Siddiqui, John Busby, UK Severe Asthma Registry
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0295493 (2023)
BackgroundThe Asthma Control Questionnaire (ACQ) is used to assess asthma symptom control. The relationship between the questionnaire items and symptom control has not been fully studied in severe asthmatic patients, and its validity for making compa
Externí odkaz:
https://doaj.org/article/c70787ad03fa4ebeb84ba63d14041e19
Publikováno v:
Energy Reports, Vol 7, Iss , Pp 176-183 (2021)
With the decarbonisation of electricity generation, large scale heat pumps are becoming an increasingly viable prospect for district heating installations. Heat pumps couple heat demands to an intermittent electricity supply with varying electricity
Externí odkaz:
https://doaj.org/article/f9d21b127b1b47f18123ab7274d7f6e7
Autor:
Bang Zheng, Luke Daines, Qing Han, John R. Hurst, Paul Pfeffer, Manu Shankar-Hari, Omer Elneima, Samantha Walker, Jeremy S. Brown, Salman Siddiqui, Jennifer K. Quint, Christopher E. Brightling, Rachael A. Evans, Louise V. Wain, Liam G. Heaney, Aziz Sheikh
Publikováno v:
European Respiratory Review, Vol 31, Iss 166 (2022)
Persistent breathlessness >28 days after acute COVID-19 infection has been identified as a highly debilitating post-COVID symptom. However, the prevalence, risk factors, mechanisms and treatments for post-COVID breathlessness remain poorly understood
Externí odkaz:
https://doaj.org/article/2a4180c1e5b842adad1db1f153ba8575