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pro vyhledávání: '"Salma Awad Mahmoud"'
Autor:
Nadya Al-Yacoub, Dilek Colak, Salma Awad Mahmoud, Maya Hammonds, Kunhi Muhammed, Olfat Al-Harazi, Abdullah M. Assiri, Jehad Al-Buraiki, Waleed Al-Habeeb, Coralie Poizat
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Al-Yacoub et al. investigate the consequences of FBXO32 mutation on dilated cardiomyopathy. ER stress, abnormal CHOP activation and CHOP-induced apoptosis with no UPR effector activation are found to underlie the FBXO32 mutation induced cardiomyopath
Externí odkaz:
https://doaj.org/article/9414570eeefe4652ac8f265170617ea4
Autor:
Kunhi Muhammed, Abdullah M. Assiri, Dilek Colak, Salma Awad Mahmoud, Maya Hammonds, Jehad Al-Buraiki, Waleed AlHabeeb, Olfat Al-Harazi, Coralie Poizat, Nadya Al-Yacoub
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology
Communications Biology
Endoplasmic reticulum (ER) stress induction of cell death is implicated in cardiovascular diseases. Sustained activation of ER-stress induces the unfolded protein response (UPR) pathways, which in turn activate three major effector proteins. We previ
Autor:
Salma Awad Mahmoud, Coralie Poizat
Publikováno v:
The Journal of Pathology
The manipulation of chromatin structure regulates gene expression and the flow of genetic information. Histone modifications and ATP-dependent chromatin remodeling together with DNA methylation are dynamic processes that modify chromatin architecture