Abstract 1679: Neoepitope screening in colorectal cancer patients by custom exome panel profiling somatic mutations

Autor: Raghavee Venkatramanan, Kerry Deutsch, Inah Golez, Pallavi Shroff, Spencer Seale, Brendan Ralph, Sally. Dow, Evan Anderson, Saman Tahir, Anjali Malge, Corey Braastad, Steven Anderson

Publikováno v: Cancer Research. 79:1679-1679

Colorectal cancer (CRC) is one of the major causes of global mortality. Recent clinical advances in T cell therapy using antibodies that block inhibitory T cell signals have been transforming cancer therapy. Studies show that somatic mutations in pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f57fdfb064a12d242f92ad4ae1aca220
https://doi.org/10.1158/1538-7445.am2019-1679

Functional profiling of the Saccharomyces cerevisiae genome

Autor: Bart Scherens, Ning Lan, Steeve Veronneau, Anna Astromoff, Matt Curtiss, Ronald W. Davis, Jeffrey N. Strathern, Marleen Voet, Johannes H. Hegemann, Ankuta Lucau-Danila, Petra Ross-Macdonald, Adam M. Deutschbauer, Françoise Foury, Greg Schimmack, Daniel D. Shoemaker, Karen Davis, Rhonda Bangham, Darlene LaBonte, Christopher J. Roberts, Zelek S. Herman, Patrick Flaherty, Stefano Campanaro, Patrice Menard, Michael Snyder, Teresa R. Ward, Adam P. Arkin, Howard Bussey, Linda Riles, Yonghong Yang, Grace Yen, Guri Giaever, K. D. Entian, Kexin Yu, Elaine M. Youngman, Sharon Sookhai-Mahadeo, Jef D. Boeke, Reginald Storms, Daniel F. Jaramillo, Giorgio Valle, José L. Revuelta, Sally Dow, Mark Johnston, Matthias Rose, Mohamed El Bakkoury, Deanna Gotte, Hong Liao, Elizabeth A. Winzeler, Brenda Shafer, Marc Lussier, Chuanyun Luo, Siew Loon Ooi, Peter Philippsen, Angela M. Chu, Guido Volckaert, Rong Mao, Peter Kötter, Keith Anderson, Ching Yun Wang, Julie Wilhelmy, Ulrich Güldener, Li Ni, Lucy Y. Liu, Mark Gerstein, David C. Lamb, Steven L. Kelly, Carla Connelly, Diane E. Kelly, Svenja Hempel, Rocío Benito, David J. Garfinkel, Bruno André, Hong Liang, Sophie Brachat

Publikováno v: Nature. 418:387-391

Determining the effect of gene deletion is a fundamental approach to understanding gene function. Conventional genetic screens exhibit biases, and genes contributing to a phenotype are often missed. We systematically constructed a nearly complete col

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bc06ae739927da5c4b01c8dabd24f4
https://doi.org/10.1038/nature00935

Abstract 3946: Stratification of metastatic colorectal cancer patients using DNA and RNA sequencing and in-silico prediction of tumor antigens for consideration in immunotherapy

Autor: Jon Oblad, Amanda Leonti, Steven Anderson, Tuuli Saloranta, Fang Yin Lo, Kellie Howard, Kathryn Shiji, Evan Anderson, Shradha Patil, Christopher Subia, Lindsey Maassel, Kerry Deutsch, Sharon Austin, Timothy J. Yeatman, Anup Madan, Sally Dow, Nicole Christopherson, Mollie McWhorter, Saman Tahir, Heather Collins

Publikováno v: Cancer Research. 76:3946-3946

Colorectal cancer (CRC) is the third most common type of cancer in the United States. Although chemotherapy, radiation and targeted therapies can improve survival rates, recent studies have shown the potential benefit of immunotherapies to improve ou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::124cdda58515914728e2467009fd66a3
https://doi.org/10.1158/1538-7445.am2016-3946

Novel Tissue Types for the Development of Genomic Biomarkers

Autor: Zinaida Sergueeva, Sally Dow, Mollie McWhorter, Mark L Parrish, Heather Collins

Publikováno v: Biomarker

Imagine a simple clinical test that can not only diagnose a disease, but that can also identify the exact, personal therapeutic regime to cure it. Not only that, imagine tests that can accurately predict the potential of developing a disease and prov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c174781f79fd90d5389318c44f9d624c
http://www.intechopen.com/articles/show/title/novel-tissue-types-for-the-development-of-genomic-biomarkers