Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sally Swift"'
Autor:
Alan Ashworth, Graeme C.M. Smith, Małgorzata Z. Zdzienicka, Andrew N. Tutt, Mark J. O'Connor, Sabrina Giavara, Sally Swift, Aneta Białkowska, Katarzyna Kluzek, Christopher J. Lord, Nicholas C. Turner, Nuala McCabe
Supplementary Tables S1 & S2 and Figures S1a & S1b from Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0275023ac8fe0956ac3319d08ea1d67d
https://doi.org/10.1158/0008-5472.22365228
https://doi.org/10.1158/0008-5472.22365228
Autor:
Alan Ashworth, Graeme C.M. Smith, Małgorzata Z. Zdzienicka, Andrew N. Tutt, Mark J. O'Connor, Sabrina Giavara, Sally Swift, Aneta Białkowska, Katarzyna Kluzek, Christopher J. Lord, Nicholas C. Turner, Nuala McCabe
Deficiency in either of the breast cancer susceptibility proteins BRCA1 or BRCA2 induces profound cellular sensitivity to the inhibition of poly(ADP-ribose) polymerase (PARP) activity. We hypothesized that the critical role of BRCA1 and BRCA2 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6284321f9a1d48891dbcad412a2fde
https://doi.org/10.1158/0008-5472.c.6494592.v1
https://doi.org/10.1158/0008-5472.c.6494592.v1
Publikováno v:
EMBO reports. 10:990-996
The breast cancer 2, early onset protein (BRCA2) is central to the repair of DNA damage by homologous recombination. BRCA2 recruits the recombinase RAD51 to sites of damage, regulates its assembly into nucleoprotein filaments and thereby promotes hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891b7438b395906877345ce6364ca636
https://doi.org/10.1038/embor.2009.126
https://doi.org/10.1038/embor.2009.126
Autor:
Sally Swift
Centered Riding is not a style of riding as are dressage, hunter seat, or Western. Rather, it is a way of reeducating a rider's mind and body to achieve greater balance in order to better communicate with the horse. Founder Sally Swift revolutionized
Autor:
Lynne Rossetto Kasper, Sally Swift
In this enticing follow-up to their first book, Lynne Rossetto Kasper and Sally Swift, host and producer of The Splendid Table public radio show, celebrate Saturday and Sunday—those two days of the week when the pressure is off, time becomes your a
Autor:
Neil, Rajan, Richard J R, Elliott, Alice, Smith, Naomi, Sinclair, Sally, Swift, Christopher J, Lord, Alan, Ashworth
Publikováno v:
Oncotarget
CYLD, an ubiquitin hydrolase, has an expanding repertoire of regulatory roles in cell signalling and is dysregulated in a number of cancers. To dissect CYLD function we used a proteomics approach to identify CYLD interacting proteins and identified M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a036c7aeccb15f9416389bad6c8eed5d
https://pubmed.ncbi.nlm.nih.gov/25565632
https://pubmed.ncbi.nlm.nih.gov/25565632
Autor:
David Bertwistle, Andrew Tutt, John Thacker, Carol S. Griffin, Gillian Ross, Anastasia Gabriel, Janet Valentine, Alan Ashworth, Sally Swift
Publikováno v:
The EMBO Journal. 20:4704-4716
Mutation of BRCA2 causes familial early onset breast and ovarian cancer. BRCA2 has been suggested to be important for the maintenance of genome integrity and to have a role in DNA repair by homology- directed double-strand break (DSB) repair. By stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6abd8b5d6fd8decad4807b372cf1f8c7
https://doi.org/10.1093/emboj/20.17.4704
https://doi.org/10.1093/emboj/20.17.4704
Publikováno v:
Human Molecular Genetics. 8:1479-1485
The protein kinase gene LKB1 has recently been identified as the gene mutated in the Peutz-Jeghers cancer predisposition syndrome. This condition is characterized by inherited susceptibility to a range of cancers but in particular those of the gastro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e9b4d33e2cbf155e3a7992c095e235b
https://doi.org/10.1093/hmg/8.8.1479
https://doi.org/10.1093/hmg/8.8.1479
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1442:394-398
EDP1 was identified as a human gene activated transcriptionally by tumour necrosis factor alpha in endothelial cells. Here we have characterised the mouse Edp1 gene. We show that the gene encodes a highly conserved protein and describe its intron/exo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f1adda2c24bdc1c08ec2b3426bb268
https://doi.org/10.1016/s0167-4781(98)00180-8
https://doi.org/10.1016/s0167-4781(98)00180-8
Autor:
Gillian Ross, P. J. Mee, E. Grigorieva, Sally Swift, David Bertwistle, Frances Connor, Victor L. J. Tybulewicz, Alan Ashworth
Publikováno v:
Nature Genetics. 17:423-430
Germline mutation of the BRCA2 gene carries a high risk of developing breast cancer. To study the function of this gene, we generated a mutation in Brca2 in mice. Unlike other mutations in the Brca2 gene, which are lethal early in embryogenesis when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66eaec833429cf1feb4f9f11da456bc1
https://doi.org/10.1038/ng1297-423
https://doi.org/10.1038/ng1297-423