Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sally Roufail"'
Autor:
Adam J. Vogrin, Neil I. Bower, Menachem J. Gunzburg, Sally Roufail, Kazuhide S. Okuda, Scott Paterson, Stephen J. Headey, Steven A. Stacker, Benjamin M. Hogan, Marc G. Achen
Publikováno v:
Cell Reports, Vol 28, Iss 8, Pp 2023-2036.e4 (2019)
Summary: Lymphatic vascular development establishes embryonic and adult tissue fluid balance and is integral in disease. In diverse vertebrate organs, lymphatic vessels display organotypic function and develop in an organ-specific manner. In all sett
Externí odkaz:
https://doaj.org/article/4ff63854e2ad428099b435bfa53eb1db
Autor:
Valeria Arcucci, Musarat Ishaq, Sally Roufail, B. Kate Dredge, Andrew G. Bert, Emily Hackett-Jones, Ruofei Liu, Katherine A. Pillman, Stephen B. Fox, Steven A. Stacker, Gregory J. Goodall, Marc G. Achen
Lymphangiogenesis (growth of new lymphatic vessels), and lymphatic remodelling more broadly, are important for disease progression in cancer, lymphedema and the pulmonary disease lymphangioleiomyomatosis. Multiple molecular pathways which signal for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39a80d7408173b1bb02ccf424f86025b
https://doi.org/10.1101/2021.12.22.473780
https://doi.org/10.1101/2021.12.22.473780
Autor:
You Fang Zhang, David J Byrne, Trifina Sofian, Stephen B. Fox, Paul Bernard Coughlin, Marc G. Achen, Sally Roufail, Sophie Paquet-Fifield, Steven A. Stacker
Publikováno v:
Growth Factors. 35:61-75
Remodelling of lymphatic vessels in tumours facilitates metastasis to lymph nodes. The growth factors VEGF-C and VEGF-D are well known inducers of lymphatic remodelling and metastasis in cancer. They are initially produced as full-length proteins req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c68493d1d31cc415d7530432018ab048
https://doi.org/10.1080/08977194.2017.1349765
https://doi.org/10.1080/08977194.2017.1349765
Autor:
Victor A Streltsov, Musarat Ishaq, Marc G. Achen, Steven P. Williams, Nicole C. Harris, Natalia Davydova, Sophie Paquet-Fifield, Steven A. Stacker, Sally Roufail, Tara Karnezis
Publikováno v:
The Journal of Biological Chemistry
VEGF-C and VEGF-D are secreted glycoproteins that induce angiogenesis and lymphangiogenesis in cancer, thereby promoting tumor growth and spread. They exhibit structural homology and activate VEGFR-2 and VEGFR-3, receptors on endothelial cells that s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6ce971c46b6a00a57440e838b267c3
https://doi.org/10.1074/jbc.m116.736801
https://doi.org/10.1074/jbc.m116.736801
Autor:
Richard A. Williams, Peter D. Sly, Teruhiko Sato, Margaret L. Hibbs, Debra J. Turner, You Fang Zhang, Jennifer L. Wilkinson-Berka, Marc G. Achen, Stephen B. Fox, Nicole C. Harris, Yinan Yuan, Sophie Paquet-Fifield, Steven A. Stacker, Sally Roufail
Publikováno v:
The Journal of Pathology. 239:152-161
Leakage of fluid from blood vessels, leading to oedema, is a key feature of many diseases including hyperoxic acute lung injury (HALI), which can occur when patients are ventilated with high concentrations of oxygen (hyperoxia). The molecular mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbfa33ea702f995e01c70125f000458f
https://doi.org/10.1002/path.4708
https://doi.org/10.1002/path.4708
Autor:
Sophie, Paquet-Fifield, Sally, Roufail, You-Fang, Zhang, Trifina, Sofian, David J, Byrne, Paul B, Coughlin, Stephen B, Fox, Steven A, Stacker, Marc G, Achen
Publikováno v:
Growth factors (Chur, Switzerland). 35(2-3)
Remodelling of lymphatic vessels in tumours facilitates metastasis to lymph nodes. The growth factors VEGF-C and VEGF-D are well known inducers of lymphatic remodelling and metastasis in cancer. They are initially produced as full-length proteins req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cdab7c86941fff8962bc880ab667499a
https://pubmed.ncbi.nlm.nih.gov/28697634
https://pubmed.ncbi.nlm.nih.gov/28697634
Autor:
Sally Roufail, Marc G. Achen, Steven A. Stacker, Scott Paterson, Benjamin M. Hogan, Stephen J. Headey, Neil I. Bower, Adam J. Vogrin, Kazuhide S. Okuda, Menachem J. Gunzburg
Publikováno v:
Cell Reports, Vol 28, Iss 8, Pp 2023-2036.e4 (2019)
Summary: Lymphatic vascular development establishes embryonic and adult tissue fluid balance and is integral in disease. In diverse vertebrate organs, lymphatic vessels display organotypic function and develop in an organ-specific manner. In all sett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573f0fc2c3909d77b3b8f81c9f5a494f
https://doi.org/10.1016/j.celrep.2019.07.055
https://doi.org/10.1016/j.celrep.2019.07.055
Autor:
Teruhiko Sato, Marc G. Achen, Julie Rothacker, Natalia Davydova, Edouard C. Nice, Karri Paavonen, Tara Karnezis, Sally Roufail, You-Fang Zhang, Nicole C. Harris, Sophie Paquet-Fifield, Steven A. Stacker
Publikováno v:
Journal of Biological Chemistry. 288:8176-8186
VEGF-D is an angiogenic and lymphangiogenic glycoprotein that can be proteolytically processed generating various forms differing in subunit composition due to the presence or absence of N- and C-terminal propeptides. These propeptides flank the cent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbc6dace037793bf19acebd2216a822
https://doi.org/10.1074/jbc.m112.439299
https://doi.org/10.1074/jbc.m112.439299
Publikováno v:
Journal of Visualized Experiments.
The analysis of receptor tyrosine kinases and their interacting ligands involved in vascular biology is often challenging due to the constitutive expression of families of related receptors, a broad range of related ligands and the difficulty of deal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec5e01741a20b6069f5ace55b11098c
https://doi.org/10.3791/53867-v
https://doi.org/10.3791/53867-v
Autor:
Steven A. Stacker, Sally Roufail, George O. Lovrecz, Natalia Davydova, Timothy E. Adams, Marc G. Achen, Victor A. Streltsov
Publikováno v:
Protein Expression and Purification. 82:232-239
Vascular endothelial growth factor-D (VEGF-D), a secreted angiogenic and lymphangiogenic glycoprotein, enhances tumor growth and metastasis in animal models, and its expression correlates with metastasis and poor patient outcome in some cancers – i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7947499d05f79049fab9aac1bc4f0a4f
https://doi.org/10.1016/j.pep.2012.01.001
https://doi.org/10.1016/j.pep.2012.01.001