Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sally R. M. Clarke"'
Autor:
Lauren Kleinert, Allison L. van Lint, Angus T. Stock, William R. Heath, Francis R. Carbone, Sally R. M. Clarke
Publikováno v:
Journal of Virology. 79:14843-14851
CD8 + T-cell persistence can be seen in ganglia harboring latent herpes simplex virus (HSV) infection. While there is some evidence that these cells suppress virus reactivation, this view remains controversial. Given that maintenance of latency by CD
Publikováno v:
Nature immunology. 3(1)
CD4(+)CD25(+) suppressor T (TS) cells play a critical role in the maintenance of peripheral tolerance. We examined here proliferative and functional responses as well as differential gene expression in T(S) cells. We found that T(S) cells were hypore
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 165(5)
TCR-self peptide:MHC interactions play a critical role in thymic positive selection, yet relatively little is known of their function in the periphery. It has been suggested that continued contact with selecting MHC molecules is necessary for long-te
Autor:
Sally R. M. Clarke
Publikováno v:
Journal of leukocyte biology. 67(5)
Control of virus infections and eradication of tumors usually involves the lytic activity of CD8+ cytotoxic T lymphocytes (CTLs). The induction of effective CTL immunity relies on several factors, one of the most important of which is CD4+ T cell hel
Autor:
Sally R. M. Clarke, Megan J. Barnden, Jacques F. A. P. Miller, Christian Kurts, William R. Heath, Francis R. Carbone
Publikováno v:
Immunology and cell biology. 78(2)
The present report provides the first extensive characterization of the OT-I TCR transgenic line, which produces MHC class I-restricted, ovalbumin-specific, CD8+ T cells (OT-I cells). These cells are shown to be positively selected in vivo in H-2b C5
Autor:
Jeffrey L. Stock, Susan Eastman, Edward D Howard, William H. Brissette, Edward F. Rosloniec, Nina Petrushova, Terry Y Nakagawa, Sally R. M. Clarke, John D. McNeish, Alexander Y. Rudensky, R. J. Griffiths, Eileen A. Elliott, Paul D. Lira
Publikováno v:
Immunity. (2):207-217
Cathepsins have been implicated in the degradation of proteins destined for the MHC class II processing pathway and in the proteolytic removal of invariant chain (Ii), a critical regulator of MHC class II function. Mice lacking the lysosomal cysteine
Autor:
Sally R. M. Clarke, Mark J. Smyth, Francis R. Carbone, Lorne F. Kastrukoff, Fumio Takei, Claerwen M. Jones, Allen S. Lau
Publikováno v:
Virology. (2):248-258
Resistance to lethal encephalitis in mice infected with HSV-1 via the oral mucosa is mouse strain dependent. In susceptible BALB/c, HSV-1 spreads throughout the CNS but in resistant BL/6 mice, virus is restricted to the brainstem. To examine the cont
Autor:
Sally R. M. Clarke, D W Johnson, David J. Kennaway, Helmut M. Hügel, H. Webb, A Tjandra, P. Royles, Francis R. Carbone
Publikováno v:
Australian Journal of Biological Sciences. 41:393
Comparison has been made between the activity of the pineal hormone melatonin, and several analogues and metabolites in inhibiting sexual development in a protein-restricted prepubertal rat model. Eleven melatonin analogues or metabolites were tested