Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Sally P Stabler"'
Autor:
Kenneth R Eyring, Brent S Pedersen, Kenneth N Maclean, Sally P Stabler, Ivana V Yang, David A Schwartz
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190916 (2018)
Environmental exposures strongly influence the development and progression of asthma. We have previously demonstrated that mice exposed to a diet enriched with methyl donors during vulnerable periods of fetal development can enhance the heritable ris
Externí odkaz:
https://doaj.org/article/9a1abd4a8b9c4053bab0b10adf0a0245
Autor:
Rachael Bok, Damian D. Guerra, Ramón A. Lorca, Sara A. Wennersten, Peter S. Harris, Abhishek K. Rauniyar, Sally P. Stabler, Kenneth N. MacLean, James R. Roede, Laura D. Brown, K. Joseph Hurt
Publikováno v:
Redox Biology, Vol 40, Iss , Pp 101827- (2021)
During pregnancy, estrogen (E2) stimulates uterine artery blood flow (UBF) by enhancing nitric oxide (NO)-dependent vasodilation. Cystathionine γ-lyase (CSE) promotes vascular NO signaling by producing hydrogen sulfide (H2S) and by maintaining the r
Externí odkaz:
https://doaj.org/article/4ba24169c8a14e86b9c9066e884fb457
Autor:
Katarina E Heyden, Joanna L Fiddler, Yuwen Xiu, Olga V Malysheva, Michal K Handzlik, Whitney N Phinney, Linsey Stiles, Sally P Stabler, Christian M Metallo, Marie A Caudill, Martha S Field
Publikováno v:
PNAS Nexus. 2
Adequate thymidylate [deoxythymidine monophosphate (dTMP) or the “T” base in DNA] levels are essential for stability of mitochondrial DNA (mtDNA) and nuclear DNA (nDNA). Folate and vitamin B12 (B12) are essential cofactors in folate-mediated one-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b28624c16e01dce0e932782d6d465fe4
https://doi.org/10.1093/pnasnexus/pgad105
https://doi.org/10.1093/pnasnexus/pgad105
Autor:
Hua Jiang, K. Joseph Hurt, Kelsey Breen, Sally P. Stabler, Robert H. Allen, David J. Orlicky, Kenneth N. Maclean
Publikováno v:
Biology Open, Vol 4, Iss 9, Pp 1154-1162 (2015)
In addition to its role in the endogenous synthesis of cysteine, cystathionine gamma-lyase (CGL) is a major physiological source of the vasorelaxant hydrogen sulfide. Cgl null mice are potentially useful for studying the influence of this compound up
Externí odkaz:
https://doaj.org/article/1692606761634b208e65e38a27e0da6c
Autor:
Kenneth N. Maclean, Hua Jiang, Whitney N. Phinney, James R. Roede, Bailey M. Mclagan, Sally P. Stabler
Publikováno v:
Molecular Genetics and Metabolism. 132:128-138
Cystathionine beta-synthase deficient homocystinuria (HCU) is a life-threatening disorder of sulfur metabolism. Our knowledge of the metabolic changes induced in HCU are based almost exclusively on data derived from plasma. In the present study, we p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::761ae7310efc824b57493638756cfc4c
https://doi.org/10.1016/j.ymgme.2021.01.003
https://doi.org/10.1016/j.ymgme.2021.01.003
Autor:
Kathrin M. Bernt, Bo-Rui Chen, Hongbo Xie, Sally P. Stabler, Aniruddha J. Deshpande, Clara Libbrecht, Andrew M. Intlekofer, Madelyn K. Bollig, Molly C. Kingsley, Simone S. Riedel, Tyler Shank, Taylor Pastuer
Publikováno v:
Blood Adv
Understanding mechanisms of cooperation between oncogenes is critical for the development of novel therapies and rational combinations. Acute myeloid leukemia (AML) cells with KMT2A-fusions and KMT2A partial tandem duplications (KMT2APTD) are known t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310667b08b59bbaa1fb3c3e45459a388
https://doi.org/10.1182/bloodadvances.2020001922
https://doi.org/10.1182/bloodadvances.2020001922
Publikováno v:
J Nutr
BACKGROUND: Neural tube defects (NTDs) occur in nervous tissue during embryogenesis when the neural tube fails to close. Approximately 70% of all human NTDs can be prevented by folic acid (FA). Altered expression and/or function of the tumor suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd931b39704b09021fec0a5459f78c4
https://doi.org/10.1093/jn/nxaa090
https://doi.org/10.1093/jn/nxaa090
Autor:
Kenneth N. Maclean, John C. Hobbins, Anne C. Porter, Sally P. Stabler, K. Joseph Hurt, Henry L. Galan, Diane L. Gumina, Michael Armstrong, Beth A. Bailey, Nichole Reisdorph
Publikováno v:
American Journal of Perinatology. 37:1084-1093
Objective Fetuses measuring below the 10th percentile for gestational age may be either constitutionally small for gestational age (SGA) or have pathologic fetal growth restriction (FGR). FGR is associated with adverse outcomes; however, identificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f3b59f7ffbb9ee852c316da00c8ad4
https://doi.org/10.1055/s-0040-1701504
https://doi.org/10.1055/s-0040-1701504
Autor:
Campbell Eric L, Daniel N. Frank, Kayla D. Battista, Thad W. Vickery, David Kitzenberg, Linda Farb, Caleb J. Kelly, Charles E. Robertson, Sean P. Colgan, Leon Zheng, Sally P. Stabler, Douglas J. Kominsky, Erica E. Alexeev
Publikováno v:
Gut Microbes
Vitamin B(12) is a critical nutrient for humans as well as microbes. Due to saturable uptake, high dose oral B(12) supplements are largely unabsorbed and reach the distal gut where they are available to interact with the microbiota. The aim of this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23310c7622d9c236cb1c4de73e2d3030
https://doi.org/10.1080/19490976.2019.1597667
https://doi.org/10.1080/19490976.2019.1597667
Autor:
Whitney N. Phinney, Sally P. Stabler, Amy K. Keating, K. Joseph Hurt, Kenneth N. Maclean, Hua Jiang
Publikováno v:
The FASEB Journal. 33:6339-6353
Classical cystathionine β-synthase-deficient homocystinuria (HCU) is a life-threatening inborn error of sulfur metabolism. Treatment for pyridoxine-nonresponsive HCU involves lowering homocysteine (Hcy) with a methionine (Met)-restricted diet and be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4121e0a1de709327aec65272fc672d4f
https://doi.org/10.1096/fj.201802069rr
https://doi.org/10.1096/fj.201802069rr