Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Sally Meiners"'
Autor:
Christopher L. Ricupero, Jeremy Griffin, Martin Grumet, Kathryn E. Uhrich, Sally Meiners, Roberto Delgado-Rivera
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 84:591-596
Microscale plasma-initiated patterning (μPIP) is a novel micropatterning technique used to create biomolecular micropatterns on polymer surfaces. The patterning method uses a polydimethylsiloxane (PDMS) stamp to selectively protect regions of an und
Autor:
Andrey Irintchev, Hsing-Yin Liu, Sally Meiners, Neha Bhagat, Melitta Schachner, Hyun Joon Lee, Gabriele Loers, Igor Jakovcevski, Grit Taschenberger, Sebastian Kügler, Jian Chen, Ronak Shah
Publikováno v:
Molecular Therapy. 18(10):1769-1777
Tenascin-C (TNC), a major component of the extracellular matrix, is strongly upregulated after injuries of the central nervous system (CNS) but its role in tissue repair is not understood. Both regeneration promoting and inhibiting roles of TNC have
Publikováno v:
Molecular and Cellular Biochemistry. 309:157-166
Activation of fibroblast growth factor receptors (FGFRs) requires the formation of a ternary complex between fibroblast growth factors (FGFs), FGFRs, and heparan sulfate proteoglycans, which are all located on the cell surface and the basement membra
Autor:
Y. Fan, Virginia M. Ayres, Abdul S. Ponery, Nathan Amor, Ijaz Ahmed, Qian Chen, Suzan L. Harris, Sally Meiners, Roberto Delgado-Rivera, Ashwin N. Babu
Publikováno v:
Polymer International. 56:1340-1348
BACKGROUND: The design of implants comprised of biodegradable electrospun nanofibers for the purpose of bridging injuries in damaged spinal cord is discussed. Electrospun nanofibers structurally mimic the extracellular matrix on which neurons and oth
Autor:
Ijaz Ahmed, Alam Nur-E-Kamal, Leroy-Fong Liu, Sally Meiners, Chao p. Lin, Yi Lisa Lyu, Anna M. Azarova
Publikováno v:
Brain Research. 1154:50-60
Failure to establish neuromuscular junctions is a major phenotype of top2beta knockout mice. However, the precise mechanism for this defect is not known. In the current study, we have investigated the role of TopIIbeta in cultured neurons. We showed
Autor:
Hsing-Yin Liu, Sally Meiners, Ping Chao Mamiya, Abdul S. Ponery, Thom Weik, Melvin Schindler, Ashwin N. Babu, Ijaz Ahmed
Publikováno v:
Journal of Biomedical Materials Research Part A. :851-860
Current methods to promote growth of cultured neurons use two-dimensional (2D) glass or polystyrene surfaces coated with a charged molecule (e.g. poly-L-lysine (PLL)) or an isolated extracellular matrix (ECM) protein (e.g. laminin-1). However, these
Autor:
Timothy H. Grafe, Atom Nur-E-Kamal, H. Young Chung, David P. Crockett, Hsing-Yin Liu, Thorn Weik, Abdul S. Ponery, Melvin Schindler, Sally Meiners, Nathan Amor, Jabeen Kamal, Ijaz Ahmed, Elizabeth Jones
Publikováno v:
Cell Biochemistry and Biophysics. 45:215-228
Research focused on deciphering the biochemical mechanisms that regulate cell proliferation and function has largely depended on the use of tissue culture methods in which cells are grown on two-dimensional (2D) plastic or glass surfaces. However, th
Autor:
Jabeen Kamal, Sally Meiners, Alam Nur-E-Kamal, Ijaz Ahmed, H. Young Chung, Timothy H. Grafe, Melvin Schindler
Publikováno v:
Biomaterials. 26:5624-5631
The purpose of this study was to design a synthetic nanofibrillar matrix that more accurately models the porosity and fibrillar geometry of cell attachment surfaces in tissues. The synthetic nanofibrillar matrices are composed of nanofibers prepared
Publikováno v:
Stem Cells. 24:426-433
The regulation of mouse embryonic stem cell (mESC) fate is controlled by the interplay of signaling networks that either promote self-renewal or induce differentiation. Leukemia inhibitory factor (LIF) is a cytokine that is required for stem cell ren
Autor:
Xin I. Wang, Alam Nur-E-Kamal, Susan M. Keenan, Takaya Satoh, Jabed Seraj, Ailing Zhang, Sally Meiners, William J. Welsh
Publikováno v:
Molecular Cancer Research. 3:297-305
Activated Cdc42-associated kinase (ACK) has been shown to be an important effector molecule for the small GTPase Cdc42. We have shown previously an essential role for Cdc42 in the transduction of Ras signals for the transformation of mammalian cells.