Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sally Mahady"'
Autor:
Adam Zwolak, Szeman Ruby Chan, Paul Harvilla, Sally Mahady, Anthony A. Armstrong, Leopoldo Luistro, Ninkka Tamot, Douglas Yamada, Mehabaw Derebe, Steven Pomerantz, Mark Chiu, Rajkumar Ganesan, Partha Chowdhury
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract TL1A (TNFSF15) is a TNF superfamily ligand which can bind the TNFRSF member death receptor 3 (DR3) on T cells and the soluble decoy receptor DcR3. Engagement of DR3 on CD4+ or CD8+ effector T cells by TL1A induces downstream signaling, leadi
Externí odkaz:
https://doaj.org/article/08da83cacee8430d962876b194440306
Autor:
Wim Bert Griet Schepens, Gilles Bignan, Leo Luistro, Sally Mahady, Monica Singer, Jocelyn Sendecki, Peter J. Connolly, James P. Edwards, Liam Campion, Kathryn Packman, Jan Willem Thuring, Hayley Ta, Nancy Bogdan, Shefali Patel, Caitlin Morgan, Daniel Jason Krosky, Emily Pierson, Glenn Van Aller, Melissa Smith, Thomas Wilde, Monicah A. Otieno, Michael J. Allegrezza, Heng-Keang Lim, Diana Wiley, Szeman Ruby Chan, Kim Staquet, Stuart L. Emanuel
Publikováno v:
Cancer Research. 80:5567A-5567A
The Stimulator of Interferon Genes (STING) protein is a key mediator of innate immunity that plays a central role in the immune response to invading pathogens (bacterial, viral) and transformed cells. A next generation human STING agonist, JNJ-‘619
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07931370687a649935a23154b8af8420
https://doi.org/10.1158/1538-7445.am2020-5567a
https://doi.org/10.1158/1538-7445.am2020-5567a
Autor:
Melissa Smith, Diana Chin, Pete Connolly, Sally Mahady, Gerald Chu, Shefali Patel, Kathryn Packman, Liam Campion, Gilles Bignan, Leopoldo Luistro, Caitlin Morgan, Anna Hughes, Stuart L. Emanuel, Szeman Chan
Publikováno v:
Cancer Research. 80:5567-5567
STING (Stimulator of Interferon Genes) is an important mediator of innate and adaptive immunity that responds to invading cytosolic bacterial and viral pathogens, and double stranded DNA from transformed cells. Activation of the cGAS-STING pathway le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37e5897ea0287207d5ac49201f5b7348
https://doi.org/10.1158/1538-7445.am2020-5567
https://doi.org/10.1158/1538-7445.am2020-5567