Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sally Loi"'
Autor:
Anna Zuk, Zhihai Si, Sally Loi, Santhosh Bommegowda, Debie Hoivik, Sanjay Danthi, Gyongyi Molnar, Vilmos Csizmadia, Michael Rabinowitz
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 383:11-24
Pharmacological inhibition of prolyl-4-hydroxylase domain (PHD) enzymes stabilizes hypoxia-inducible factors (HIFs), transcription factors that activate target genes that, among others, increase erythropoietin (EPO) synthesis, resulting in the produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212ebca1120f2d693be7ff991a9b7695
https://doi.org/10.1124/jpet.122.001126
https://doi.org/10.1124/jpet.122.001126
Autor:
Jean B. Regard, Tyler J. Harrison, Jake Axford, Laura Axford, Lac Lee, Xianglin Ren, Lin Deng, Aimee Reynolds, Justin Mao, Qian Liu, Anup Patnaik, Evan Cohick, Micah Hollis-Symynkywicz, Sally Loi, Simone Riek, Una McKeever, David Dunstan, MooJe Sung, Nathaniel F. Ware, Alan P. Brown, Lawrence G. Hamann, Jovita Marcinkeviciene, Andrew W. Patterson, Martin L. Marro
Publikováno v:
Biochemical Pharmacology. 209:115418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ca359f22e4e005b5d162fd46603ee41
https://doi.org/10.1016/j.bcp.2023.115418
https://doi.org/10.1016/j.bcp.2023.115418
Autor:
Jean B. Regard, Tyler J. Harrison, Jake Axford, Laura Axford, Lac Lee, Xianglin Ren, Lin Deng, Aimee Reynolds, Justin Mao, Qian Liu, Anup Patnaik, Evan Cohick, Micah Hollis-Symynkywicz, Sally Loi, Simone Riek, David Dunstan, MooJe Sung, Nathaniel F. Ware, Lawrence G. Hamann, Jovita Marcinkeviciene, Andrew W. Patterson, Martin L. Marro
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1104177874617840d976f7da34edc3f
https://doi.org/10.2139/ssrn.4198908
https://doi.org/10.2139/ssrn.4198908
Autor:
Laura Axford, Micah Hollis-Symynkywicz, Jovita Marcinkeviciene, Lac Lee, Julien Papillon, Tyler Harrison, Jean Regard, Xianglin Ren, Lin Deng, Lawrence G. Hamann, Evan Cohick, Sally Loi, Sam Kecman, Martin L. Marro, Natalie Dales, Andrew Patterson, Anup Patnaik
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115548
Myeloperoxidase (MPO) activity and subsequent generation of hypochlorous acid has been associated with the killing of host-invading microorganisms (e.g. bacteria, viruses, and fungi). However, during oxidative stress, high MPO activity can damage hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa62aeab41b2bdf6e6218857945f77cb
https://doi.org/10.1016/j.bmc.2020.115548
https://doi.org/10.1016/j.bmc.2020.115548
Autor:
Sally Loi, Lac Lee, Jean Regard, Dominique Custeau, Andrew Patterson, Lin Deng, Julien Papillon, Aimee Reynolds, Tyler Harrison, Micah Hollis-Symynkywicz, Jovita Marcinkeviciene, Lawrence G. Hamann, Anup Patnaik, Xianglin Ren, Jutta Blank, Nigel Casson, Laura Axford, Toshiyuki Honda, Lisa Ames, Lihe Zhang, Martin L. Marro
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 367(1)
Myeloperoxidase (MPO) is a leukocyte-derived redox enzyme that has been linked to oxidative stress and damage in many inflammatory states, including cardiovascular disease. We have discovered aminopyridines that are potent mechanism-based inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444de565ea988076b4b032134228dce7
https://pubmed.ncbi.nlm.nih.gov/30076263
https://pubmed.ncbi.nlm.nih.gov/30076263