Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Sally L George"'
Autor:
Sally L George, Federica Lorenzi, David King, Sabine Hartlieb, James Campbell, Helen Pemberton, Umut H Toprak, Karen Barker, Jennifer Tall, Barbara Martins da Costa, Marlinde L van den Boogaard, M Emmy M Dolman, Jan J Molenaar, Helen E Bryant, Frank Westermann, Christopher J Lord, Louis Chesler
Publikováno v:
EBioMedicine, Vol 59, Iss , Pp 102971- (2020)
Background: In neuroblastoma, genetic alterations in ATRX, define a distinct poor outcome patient subgroup. Despite the need for new therapies, there is a lack of available models and a dearth of pre-clinical research. Methods: To evaluate the impact
Externí odkaz:
https://doaj.org/article/43e6d2e114774272b2793ae20c2d02f1
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100156- (2024)
The clinical behaviour of neuroblastoma ranges from spontaneous tumour regression or maturation into benign ganglioneuroma to fatal progression despite intensive treatment [1,2]. The mechanisms underlying the distinct phenotypes have remained uncerta
Externí odkaz:
https://doaj.org/article/e94637699a77469fb4b11567edb2675b
Autor:
Reda Stankunaite, Lynley V. Marshall, Fernando Carceller, Louis Chesler, Michael Hubank, Sally L. George
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Circulating cell-free DNA (cfDNA) analysis has the potential to revolutionise the care of patients with cancer and is already moving towards standard of care in some adult malignancies. Evidence for the utility of cfDNA analysis in paediatric cancer
Externí odkaz:
https://doaj.org/article/08dbef97b1da4600a388a638049530a0
Autor:
Gudrun Schleiermacher, Deborah A. Tweddle, Louis Chesler, Sally L. George, Olivier Delattre, Didier Surdez, Angel M. Carcaboso, Fariba Nemati, Didier Decaudin, Isabelle Janoueix-Lerosey, Cécile Pierre-Eugène, Maria Eugénia Marques Da Costa, Birgit Geoerger, Alexandra Saint-Charles, Elnaz Saberi-Ansari, Yasmine Iddir, Jaydutt Bhalshankar, Pierre Gestraud, Elaine Del Nery, Angharad Goodman, Simran Dhariwal, J. Ciaran Hutchinson, Sumana Shrestha, Karen Barker, Barbara Martins Da Costa, Yann Jamin, Evon Poon, Harvey Che, Qiong Gao, Elizabeth Calton, Chiara Gorrini, Angela Bellini, Lindi Chen, Irene Jiménez, Elizabeth R. Tucker
Cell line growth curves and PDX data for idasanutlin combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ade0a51c8dfce371b3bd0d4b0a103fc
https://doi.org/10.1158/1078-0432.22494934.v1
https://doi.org/10.1158/1078-0432.22494934.v1
Autor:
Gudrun Schleiermacher, Deborah A. Tweddle, Louis Chesler, Sally L. George, Olivier Delattre, Didier Surdez, Angel M. Carcaboso, Fariba Nemati, Didier Decaudin, Isabelle Janoueix-Lerosey, Cécile Pierre-Eugène, Maria Eugénia Marques Da Costa, Birgit Geoerger, Alexandra Saint-Charles, Elnaz Saberi-Ansari, Yasmine Iddir, Jaydutt Bhalshankar, Pierre Gestraud, Elaine Del Nery, Angharad Goodman, Simran Dhariwal, J. Ciaran Hutchinson, Sumana Shrestha, Karen Barker, Barbara Martins Da Costa, Yann Jamin, Evon Poon, Harvey Che, Qiong Gao, Elizabeth Calton, Chiara Gorrini, Angela Bellini, Lindi Chen, Irene Jiménez, Elizabeth R. Tucker
Supplementary methods, supplementary tables, supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469607ba4ba88232995ac733d8951161
https://doi.org/10.1158/1078-0432.22494931
https://doi.org/10.1158/1078-0432.22494931
Autor:
Louis Chesler, John Anderson, Simon P. Robinson, Neil Sebire, Gareth J. Veal, Stefano Lise, Yann Jamin, Evon Poon, Barbara M. da Costa, Elizabeth A. Calton, Bliss Buttery, Laura S. Danielson, Hannah T. Webber, Till Möcklinghoff, Philip Berry, Albert Hallsworth, Laura M. Smith, Dimitrios Kleftogiannis, Magdalena Zarowiecki, James Campbell, Colin Kwok, Sally L. George, Karen T. Barker, Gilberto S. Almeida, Orli Yogev
Th-MYCNCPM32 tumors show increased ECM and increased levels of Tnrc6 but not TK1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a648d0ca024574d7a3a5b2e0dad7b6
https://doi.org/10.1158/0008-5472.22422047
https://doi.org/10.1158/0008-5472.22422047
Autor:
Louis Chesler, John Anderson, Simon P. Robinson, Neil Sebire, Gareth J. Veal, Stefano Lise, Yann Jamin, Evon Poon, Barbara M. da Costa, Elizabeth A. Calton, Bliss Buttery, Laura S. Danielson, Hannah T. Webber, Till Möcklinghoff, Philip Berry, Albert Hallsworth, Laura M. Smith, Dimitrios Kleftogiannis, Magdalena Zarowiecki, James Campbell, Colin Kwok, Sally L. George, Karen T. Barker, Gilberto S. Almeida, Orli Yogev
Supplementary materials and methods Supplementary figures legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6902c98ba2298575bfc2976e5bd6a9
https://doi.org/10.1158/0008-5472.22422053.v1
https://doi.org/10.1158/0008-5472.22422053.v1
Autor:
Louis Chesler, John Anderson, Simon P. Robinson, Neil Sebire, Gareth J. Veal, Stefano Lise, Yann Jamin, Evon Poon, Barbara M. da Costa, Elizabeth A. Calton, Bliss Buttery, Laura S. Danielson, Hannah T. Webber, Till Möcklinghoff, Philip Berry, Albert Hallsworth, Laura M. Smith, Dimitrios Kleftogiannis, Magdalena Zarowiecki, James Campbell, Colin Kwok, Sally L. George, Karen T. Barker, Gilberto S. Almeida, Orli Yogev
Table S1. RNA sequencing sample overview and accession numbers Table S2. RNA sequencing sample mapping statistics and raw read counts Table S3. RNA sequencing differential expression results Table S4. RNA sequencing GSEA results Table S5. Mouse-Human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061f3dda00ba1af345e17eaa70e18d80
https://doi.org/10.1158/0008-5472.22422032
https://doi.org/10.1158/0008-5472.22422032
Autor:
Louis Chesler, John Anderson, Simon P. Robinson, Neil Sebire, Gareth J. Veal, Stefano Lise, Yann Jamin, Evon Poon, Barbara M. da Costa, Elizabeth A. Calton, Bliss Buttery, Laura S. Danielson, Hannah T. Webber, Till Möcklinghoff, Philip Berry, Albert Hallsworth, Laura M. Smith, Dimitrios Kleftogiannis, Magdalena Zarowiecki, James Campbell, Colin Kwok, Sally L. George, Karen T. Barker, Gilberto S. Almeida, Orli Yogev
Th-MYCNCPM32 tumors and derived cell lines show enhancement of mesenchymal markers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca24d1941f1fe90751d12fde7808dcc2
https://doi.org/10.1158/0008-5472.22422041.v1
https://doi.org/10.1158/0008-5472.22422041.v1
Autor:
Louis Chesler, John Anderson, Simon P. Robinson, Neil Sebire, Gareth J. Veal, Stefano Lise, Yann Jamin, Evon Poon, Barbara M. da Costa, Elizabeth A. Calton, Bliss Buttery, Laura S. Danielson, Hannah T. Webber, Till Möcklinghoff, Philip Berry, Albert Hallsworth, Laura M. Smith, Dimitrios Kleftogiannis, Magdalena Zarowiecki, James Campbell, Colin Kwok, Sally L. George, Karen T. Barker, Gilberto S. Almeida, Orli Yogev
Resistant tumors show recurrent copy number aberrations and a tendency towards the neuroblastoma mesenchymal gene expression signature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b84c6053effce3c8ab2845976cece01
https://doi.org/10.1158/0008-5472.22422044.v1
https://doi.org/10.1158/0008-5472.22422044.v1