Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sally K. Nelson"'
Autor:
Michael Benatar, Terry Heiman-Patterson, Merit Cudkowicz, Stephen Apple, Stanley H. Appel, James D. Berry, Jeremy M. Shefner, Jurjen Westra, Robert Bowser, Sally K. Nelson, Angela Genge, Clifton L. Gooch, Benjamin Rix Brooks, Wendy Agnese, Charlotte Merrill
Publikováno v:
Neurology: Clinical Practice
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectivesTo identify putative biomarkers that may serve as quantifiable, biological, nonclinical measures of the pharmacodynamic effect of edaravone in amyotrophic lateral sclerosis (ALS) and to report real-world treatment outcomes.MethodsThis is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45308952c70a6b766dcfef6cb5aa5224
https://pubmed.ncbi.nlm.nih.gov/34476128
https://pubmed.ncbi.nlm.nih.gov/34476128
Autor:
Larry Gold, Deborah Ayers, Jennifer Bertino, Christopher Bock, Ashley Bock, Edward N Brody, Jeff Carter, Andrew B Dalby, Bruce E Eaton, Tim Fitzwater, Dylan Flather, Ashley Forbes, Trudi Foreman, Cate Fowler, Bharat Gawande, Meredith Goss, Magda Gunn, Shashi Gupta, Dennis Halladay, Jim Heil, Joe Heilig, Brian Hicke, Gregory Husar, Nebojsa Janjic, Thale Jarvis, Susan Jennings, Evaldas Katilius, Tracy R Keeney, Nancy Kim, Tad H Koch, Stephan Kraemer, Luke Kroiss, Ngan Le, Daniel Levine, Wes Lindsey, Bridget Lollo, Wes Mayfield, Mike Mehan, Robert Mehler, Sally K Nelson, Michele Nelson, Dan Nieuwlandt, Malti Nikrad, Urs Ochsner, Rachel M Ostroff, Matt Otis, Thomas Parker, Steve Pietrasiewicz, Daniel I Resnicow, John Rohloff, Glenn Sanders, Sarah Sattin, Daniel Schneider, Britta Singer, Martin Stanton, Alana Sterkel, Alex Stewart, Suzanne Stratford, Jonathan D Vaught, Mike Vrkljan, Jeffrey J Walker, Mike Watrobka, Sheela Waugh, Allison Weiss, Sheri K Wilcox, Alexey Wolfson, Steven K Wolk, Chi Zhang, Dom Zichi
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15004 (2010)
The interrogation of proteomes ("proteomics") in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology and medicine.We present a new aptamer-based proteomic technology for biomarker discovery capable of simultane
Externí odkaz:
https://doaj.org/article/60cf7be12d92486ea0f48de33701edfa
Autor:
Steven J. Kiddle, Sally K. Nelson, Giovanni Coppola, Daniel H. Geschwind, Patrizia Mecocci, Hilkka Soininen, Stephen Newhouse, Bruno Vellas, Iwona Kłoszewska, Magda Tsolaki, Petroula Proitsi, Caroline Johnston, Katie Lunnon, Nicola Voyle, Martina Sattlecker, Richard Dobson, Simon Lovestone, Justin Tao Wen Chiam, Angela Hodges
Publikováno v:
Chiam, J T W, Lunnon, K, Voyle, N, Proitsi, P, Coppola, G, Geschwind, D, Nelson, S, Johnston, C, Soininen, H, Kłoszewska, I, Mecocci, P, Tsolaki, M, Vellas, B, Hodges, A, Lovestone, S, Newhouse, S, Dobson, R J B, Kiddle, S J & Sattlecker, M 2015, ' No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease ', JOURNAL OF ALZHEIMERS DISEASE, vol. 47, no. 3, pp. 741-750 . https://doi.org/10.3233/JAD-150289
BACKGROUND: There is an urgent need to discover Alzheimer's disease (AD) biomarkers that are both easily measured and reliable. Research into blood-based biomarkers for AD using transcriptomics and proteomics has been an attractive and promising area
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f258a5baf339c887b38ba292f410ef2
https://doi.org/10.3233/jad-150289
https://doi.org/10.3233/jad-150289
Autor:
Sally K. Nelson, Yetrib Hathout, Bob Mehler, Heather Gordish-Dressman, Linda H. Cripe, Edward N. Brody, Angela Lorts, Malti Nikrad, H. Lee Sweeney, Craig M. McDonald, Robert Kirk DeLisle, Paula R. Clemens, Yvonne M. Kobayashi, Erik K Henricson, Steve C.R. Williams, Pat Furlong, Fintan Steele, Jean K. Mah, Lauren P. Hache, Eric P. Hoffman, Larry Gold, Britta Singer, David Sterling
Publikováno v:
Proceedings of the National Academy of Sciences. 112:7153-7158
Serum biomarkers in Duchenne muscular dystrophy (DMD) may provide deeper insights into disease pathogenesis, suggest new therapeutic approaches, serve as acute read-outs of drug effects, and be useful as surrogate outcome measures to predict later cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb8504683f7bfed720b6e16aea45b2a
https://doi.org/10.1073/pnas.1507719112
https://doi.org/10.1073/pnas.1507719112
Autor:
Stephen Newhouse, Ana Viñuela, Massimo Mangino, Simon Lovestone, Claire J. Steves, Nicola Voyle, Patrizia Mecocci, Maria Psatha, Martina Sattlecker, Bruno Vellas, Tim D. Spector, Ana M. Valdes, Richard Dobson, Iwona Kłoszewska, Hilkka Soininen, Stephen Williams, Steven J. Kiddle, Alfonso Buil, Magda Tsolaki, Cristina Menni, Sally K. Nelson
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences; Vol 70
Menni, C, Kiddle, S J, Mangino, M, Viñuela, A, Psatha, M, Steves, C, Sattlecker, M, Buil, A, Newhouse, S, Nelson, S, Williams, S, Voyle, N, Soininen, H, Kloszewska, I, Mecocci, P, Tsolaki, M, Vellas, B, Lovestone, S, Spector, T D, Dobson, R & Valdes, A M 2015, ' Circulating Proteomic Signatures of Chronological Age ', Journals of Gerontology Series. A, Biological Sciences and Medical Sciences, vol. 70, no. 7, pp. 809-816 . https://doi.org/10.1093/gerona/glu121
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences; Vol 70
Menni, C, Kiddle, S J, Mangino, M, Viñuela, A, Psatha, M, Steves, C, Sattlecker, M, Buil, A, Newhouse, S, Nelson, S, Williams, S, Voyle, N, Soininen, H, Kloszewska, I, Mecocci, P, Tsolaki, M, Vellas, B, Lovestone, S, Spector, T D, Dobson, R & Valdes, A M 2015, ' Circulating Proteomic Signatures of Chronological Age ', Journals of Gerontology Series. A, Biological Sciences and Medical Sciences, vol. 70, no. 7, pp. 809-816 . https://doi.org/10.1093/gerona/glu121
To elucidate the proteomic features of aging in plasma, the subproteome targeted by the SOMAscan assay was profiled in blood samples from 202 females from the TwinsUK cohort. Findings were replicated in 677 independent individuals from the AddNeuroMe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96874dec5315c84a8ed525ca93189c6b
Autor:
Patrizia Mecocci, Sally K. Nelson, Andrew Simmons, Bruno Vellas, Angela Hodges, Stephen Newhouse, Richard Dobson, Eric Westman, Hilkka Soininen, Steven J. Kiddle, Chantal Bazenet, Simon Lovestone, Stephen Williams, Magda Tsolaki, Caroline Johnston, Petroula Proitsi, Martina Sattlecker, Iwona Kłoszewska
Publikováno v:
King's College London
A blood-based protein biomarker, or set of protein biomarkers, that could predict onset and progression of Alzheimer's disease (AD) would have great utility; potentially clinically, but also for clinical trials and especially in the selection of subj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2342f91815840f019856233a447146
https://doi.org/10.3233/jad-130380
https://doi.org/10.3233/jad-130380
Autor:
Sally K. Nelson, Elaine R. Peskind, Alex Stewart, Stephan Kraemer, Geoffrey S. Baird, Tracy R. Keeney, Stephen Williams, Thomas J. Montine
Publikováno v:
The American Journal of Pathology. 180(2):446-456
An important precondition for the successful development of diagnostic assays of cerebrospinal fluid (CSF) biomarkers of age-related neurodegenerative diseases is an understanding of the dynamic nature of the CSF proteome during the normal aging proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0575a910ff2c2b4257fcc95b2cade7
Publikováno v:
Free Radical Biology and Medicine. 40:341-347
A composition consisting of extracts of five widely studied medicinal plants (Protandim) was administered to healthy human subjects ranging in age from 20 to 78 years. Individual ingredients were selected on the basis of published findings of inducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09633b5ee33c05d69ac985080cb83755
https://doi.org/10.1016/j.freeradbiomed.2005.08.043
https://doi.org/10.1016/j.freeradbiomed.2005.08.043
Publikováno v:
Biomedicine & Pharmacotherapy. 59:149-157
Every transplant is a reperfused organ and, therefore, undergoes some degree of oxidative damage. Postischemic reperfusion injury results in non-specific free radical-mediated acute endothelial damage, cell death and organ failure. The endothelium is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92563b615952b93a1bdeeb109f7f900e
https://doi.org/10.1016/j.biopha.2005.03.007
https://doi.org/10.1016/j.biopha.2005.03.007
Autor:
Lawrence D. Horwitz, Hirohisa Kato, Sally K. Nelson, Farin Amersi, Ronald W. Busuttil, Xiu Da Shen, Jerzy W. Kupiec-Weglinski, Marcus A. Horwitz, Judy Melinek
Publikováno v:
Proceedings of the National Academy of Sciences. 99:8915-8920
Ischemia/reperfusion (I/R) injury is a serious potential threat to outcomes in organ transplantation and other clinical arenas in which there is temporary interruption of blood flow. I/R is a frequent cause of primary failure in organ transplantation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c7d200a9dd63f220dc44df67ad3dd8
https://doi.org/10.1073/pnas.132026099
https://doi.org/10.1073/pnas.132026099