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pro vyhledávání: '"Sally J. Rowe"'
Publikováno v:
Developmental Biology. 205:224-232
Neurotransmitters regulate neuronal function in the nervous system and modulation of their synthesis, release, and binding by immature neurons and their targets is a major part of nervous system development. We propose that the neurotransmitter norad
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1555-1558
A number of indole-derived melatonin analogues have been prepared lacking the C-5 methoxyl group. Many of these analogues are melatonin-receptor agonists and the previous assumption that the 5-OMe group was required for biological activity appears to
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1559-1564
A number of indole derived melatonin analogues have been prepared with the C-3 amidoethane side chain partially constrained by incorporation in a ring. The biological activity has been correlated with the conformation of the “side chain”, the nat
Publikováno v:
Development (Cambridge, England). 119(4)
The possibility that monoamines might act as signalling molecules during the early development of the nervous system has been examined in embryos of the amphibian Xenopus laevis. The distributions of 5-hydroxytryptamine, dopamine, noradrenaline and t