Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sally E. Purdom-Dickinson"'
Publikováno v:
Cardiovascular Toxicology. 12:108-114
NAD(P)H: quinone oxidoreductase 1 (NQO1) is a ubiquitous flavoenzyme that catalyzes two-electron reduction of various quinones by utilizing NAD(P)H as an electron donor. Our previous study found that progesterone (PG) can protect cardiomyocytes from
Publikováno v:
Journal of Molecular and Cellular Cardiology. 42:159-176
Mild or low doses of oxidants are known to prime cells towards resistance against further damage. In cardiomyocytes, we found that pretreatment with 100 microM H(2)O(2) prevents the cells from apoptosis induced by doxorubicin (Dox). Affymetrix microa
Publikováno v:
Molecular pharmacology. 72(4)
Nf-E2 related factor-2 (Nrf2) is a basic leucine zipper transcription factor that binds and activates the antioxidant response element (ARE) in the promoters of many antioxidant and detoxification genes. We found that H(2)O(2) treatment caused a rapi