Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sally D. Pennypacker"'
Autor:
Daniel D. Bikle, Hong Fan, Zhongjian Xie, Chandrama Shrestha, Lusha Li, Yuanyuan Tang, Qin Zeng, Sally D. Pennypacker
Publikováno v:
BioMed Research International, Vol 2016 (2016)
BioMed Research International
BioMed Research International
Extracellular calcium is a major regulator of keratinocyte differentiation in vitro and appears to play that role in vivo, but the mechanism is unclear. We have previously demonstrated that, following calcium stimulation, PIP5K1αis recruited by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8e0f567c7af4b733441f26d83bd799
https://doi.org/10.1155/2016/3062765
https://doi.org/10.1155/2016/3062765
Autor:
Richard Sun, Yoshikazu Uchida, Lillian C. Adame, Dusko Ilic, Kyungho Park, Anna Celli, Theodora M. Mauro, Debra Crumrine, Kenneth R. Feingold, Sally D. Pennypacker, Peter M. Elias, Melanie Hupe
Publikováno v:
Tissue engineering. Part C, Methods, vol 21, iss 1
Sun, R; Celli, A; Crumrine, D; Hupe, M; Adame, LC; Pennypacker, SD; et al.(2015). Lowered humidity produces human epidermal equivalents with enhanced barrier properties. Tissue Engineering-Part C: Methods, 21(1), 15-22. doi: 10.1089/ten.tec.2014.0065. UCSF: Retrieved from: http://www.escholarship.org/uc/item/2m88t0vc
Sun, R; Celli, A; Crumrine, D; Hupe, M; Adame, LC; Pennypacker, SD; et al.(2015). Lowered humidity produces human epidermal equivalents with enhanced barrier properties. Tissue Engineering-Part C: Methods, 21(1), 15-22. doi: 10.1089/ten.tec.2014.0065. UCSF: Retrieved from: http://www.escholarship.org/uc/item/2m88t0vc
© 2015 Mary Ann Liebert, Inc. Multilayered human keratinocyte cultures increasingly are used to model human epidermis. Until now, studies utilizing human epidermal equivalents (HEEs) have been limited because previous preparations do not establish a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90ab64ea67137b23b0dd7803fe1c126
https://doi.org/10.1089/ten.tec.2014.0065
https://doi.org/10.1089/ten.tec.2014.0065
Autor:
Liyan Liao, Ying Chen, Jian Peng, Sally D. Pennypacker, Zhongjian Xie, Xiaoping Gao, Sheng-hua Zhou
Publikováno v:
Journal of Dermatological Science. 67:199-202
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9029072731c03305d748e51cd7ef847b
https://doi.org/10.1016/j.jdermsci.2012.06.002
https://doi.org/10.1016/j.jdermsci.2012.06.002
Publikováno v:
Oncogene. 31:5090-5098
One of the key drivers for squamous cell carcinoma (SCC) proliferation is activation of the epidermal growth factor receptor (EGFR), a known proto-oncogene. However, the mechanism of EGFR-dependent SCC proliferation remains unclear. Our previous stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e79bc83dc8abdde466498e44476baf3
https://doi.org/10.1038/onc.2012.10
https://doi.org/10.1038/onc.2012.10
Publikováno v:
Biochemical and Biophysical Research Communications. 397:296-300
The epidermal growth factor receptor (EGFR) is a key driver in the process of squamous cell carcinoma (SCC) cell mitogenesis. Phospholipase C-gamma1 (PLC-gamma1) is a downstream target of EGFR signaling, but the role and necessity of PLC-gamma1 in EG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d629dbf8be4831b8dcc501135d73e6f
https://doi.org/10.1016/j.bbrc.2010.05.103
https://doi.org/10.1016/j.bbrc.2010.05.103
Publikováno v:
Journal of Investigative Dermatology. 127(4):874-880
It has long been known that the active metabolite of vitamin D, 1,25 dihydroxyvitamin D(3), stimulates differentiation and inhibits proliferation in epidermal keratinocytes through interaction with the vitamin D receptor (VDR). VDR functions through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cadf6af28c21d30052297841d33adab
Autor:
Paul T. Spellman, Jon C. Aster, Yong Zou, Mimansa Sharma, Isaac M. Neuhaus, Charlotte M. Proby, Pui-Yan Kwok, Lakshmi Jakkula, Joe W. Gray, Stephen C. Blacklow, Kyunghee Park, Philip E. LeBoit, Joe S Hur, Laura J. Bayston, Zachary Sanborn, James E. Cleaver, Wilson Liao, Swapna S. Vemula, Theodora M. Mauro, Pierre P. Massion, Nicholas J. Wang, Andrew P. South, Jeffrey P. North, Allen E. Bale, Eric A. Collisson, Irene M. Leigh, Sally D. Pennypacker, Raymond J. Cho, Nam Huh, Sarah T. Arron, David Haussler, Kelly L. Arnett, Patricia B. Gordon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(43)
Squamous cell carcinomas (SCCs) are one of the most frequent forms of human malignancy, but, other than TP53 mutations, few causative somatic aberrations have been identified. We identified NOTCH1 or NOTCH2 mutations in ∼75% of cutaneous SCCs and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242d4f78e7880c188c67862a2cd12aa9
https://pubmed.ncbi.nlm.nih.gov/22006338
https://pubmed.ncbi.nlm.nih.gov/22006338
Phospholipase C-gamma1 (PLC-gamma1) is a multiple-domain protein and plays an important role in epidermal growth factor (EGF)-induced cell mitogenesis, but the underlying mechanism is unclear. We have previously demonstrated that PLC-gamma1 is requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425d399bc425bf093483867ed1810b26
https://europepmc.org/articles/PMC2918663/
https://europepmc.org/articles/PMC2918663/
Publikováno v:
Biochemical and biophysical research communications. 399(3)
Phospholipase C-gamma1 (PLC-gamma1), a tyrosine kinase substrate, has been implicated in the pathway for the epidermal growth factor receptor (EGFR)-induced cell migration. However, the underlying mechanism by which PLC-gamma1 mediates EGFR-induced c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8898d0d4b727d508a8fcafb86a3b8a2
https://pubmed.ncbi.nlm.nih.gov/20674545
https://pubmed.ncbi.nlm.nih.gov/20674545
Autor:
Arnon Rosenthal, Frederic J. de Sauvage, Jeannette M. Bonifas, Sally D. Pennypacker, Mickey P. Williams, Andrew P. McMahon, Ervin H. Epstein, Pao-Tien Chuang
Publikováno v:
Journal of Investigative Dermatology. (5):739-742
Mutations in hedgehog signaling pathway genes, especially PTC1 and SMO, are pivotal to the development of basal cell carcinomas. The study of basal cell carcinoma gene expression not only may elucidate mechanisms by which hedgehog signaling abnormali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501130d05b4047da318e719e67e7cf0f